DK297585A - 1-methylcarbapenemer med externt alkylerede mono- eller bicycliske kvaternaere heteroarylalkylthio 2-substituenter samt laegemiddel indeholdende saadanne forbindelser - Google Patents
1-methylcarbapenemer med externt alkylerede mono- eller bicycliske kvaternaere heteroarylalkylthio 2-substituenter samt laegemiddel indeholdende saadanne forbindelser Download PDFInfo
- Publication number
- DK297585A DK297585A DK297585A DK297585A DK297585A DK 297585 A DK297585 A DK 297585A DK 297585 A DK297585 A DK 297585A DK 297585 A DK297585 A DK 297585A DK 297585 A DK297585 A DK 297585A
- Authority
- DK
- Denmark
- Prior art keywords
- alkyled
- heteroarylalkylthio
- substitutes
- mono
- externally
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/32—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62682184A | 1984-07-02 | 1984-07-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK297585D0 DK297585D0 (da) | 1985-07-01 |
| DK297585A true DK297585A (da) | 1986-03-14 |
Family
ID=24512002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK297585A DK297585A (da) | 1984-07-02 | 1985-07-01 | 1-methylcarbapenemer med externt alkylerede mono- eller bicycliske kvaternaere heteroarylalkylthio 2-substituenter samt laegemiddel indeholdende saadanne forbindelser |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0170073A1 (de) |
| JP (1) | JPS6183183A (de) |
| CA (1) | CA1273012A (de) |
| DK (1) | DK297585A (de) |
| ES (1) | ES8609336A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4880922A (en) * | 1985-11-22 | 1989-11-14 | Bristol-Myers Company | Carbapenems with quaternized heterothioalkylthio substitution at position 2 |
| JPS6363680A (ja) * | 1986-09-05 | 1988-03-22 | Nippon Redarii Kk | （１ｒ）−１−メチルカルバペネム−３−カルボン酸誘導体 |
| DE3640715A1 (de) * | 1986-11-28 | 1988-06-09 | Bayer Ag | Benzazolylthio-carbapenem-antibiotika |
| JPS63255281A (ja) * | 1987-04-11 | 1988-10-21 | Nippon Redarii Kk | （１ｒ，５ｓ，６ｓ）−２−〔（ピラジニウム−２−イル）メチル〕チオ−６−〔（ｒ）−１−ヒドロキシエチル〕−１−メチル−カルバペネム−３−カルボキシレ−ト |
| US4866171A (en) * | 1987-04-11 | 1989-09-12 | Lederle (Japan), Ltd. | (1R,5S,6S)-2-[(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazolium-6-yl)]thio-6-[R-1-hydroxyethyl]-1-methyl-carbapenum-3-carboxylate |
| JPS63255284A (ja) * | 1987-04-11 | 1988-10-21 | Nippon Redarii Kk | （１ｒ，５ｓ，６ｓ）−２−〔（置換ピリジニウム−２−イル）メチル〕チオ−６−〔（ｒ）−１−ヒドロキシエチル〕−１−メチル−カルバペネム−３−カルボキシレ−ト |
| JPS6425779A (en) * | 1987-04-11 | 1989-01-27 | Lederle Japan Ltd | (1r,5s,6s)-2-substituted-thio-6-((r)-1-hydroxyethyl)-1-methyl -carbapenem-3-carboxylic acid derivative |
| JPS6425778A (en) * | 1987-04-11 | 1989-01-27 | Lederle Japan Ltd | (1r,5s,6s)-2-((1,2,3-thiadiazolium-4-yl)methyl)thio-6-((r)-1-hydroxyethyl)-1-methyl-carbapenem-3-carboxylate |
| JPS63255282A (ja) * | 1987-04-11 | 1988-10-21 | Nippon Redarii Kk | （１ｒ，５ｓ，６ｓ）−２−〔（チアゾリウム−２−イル）または（イミダゾリウム−２−イル）メチル〕チオ−６−〔（ｒ）−１−ヒドロキシエチル〕−１−メチル−カルバペネム−３−カルボキシレ−ト |
| DK168047B1 (da) * | 1987-12-07 | 1994-01-24 | Lederle Japan Ltd | (1r,5s,6s)-2-substitueret thio-6-oe(r)-1-hydroxyethylaa-1-methyl-carbapenem-3-carboxylsyrederivater, fremgangsmaade til remstilling deraf, midler og praeparater indeholdende den krystallinske forbindelse samt dens anvendelse. |
| JPH0262877A (ja) * | 1988-08-29 | 1990-03-02 | Lederle Japan Ltd | カルバペネム化合物 |
| WO1991000864A1 (en) * | 1989-07-07 | 1991-01-24 | Banyu Pharmaceutical Co., Ltd. | Carbapenem derivatives |
| US5227376A (en) * | 1990-02-14 | 1993-07-13 | Sumitomo Pharmaceuticals Co., Ltd. | β-lactam compounds and their production |
| US5496816A (en) * | 1994-03-14 | 1996-03-05 | Merck & Co., Inc. | Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment |
| CA2241321A1 (en) | 1996-01-12 | 1997-07-17 | Tetsuo Miwa | Carbapenem compounds, their production and use |
| DE19840943A1 (de) * | 1998-09-08 | 2000-03-09 | Aventis Res & Tech Gmbh & Co | Verfahren zur Herstellung von Derivaten des 4-Alkylsulfinylmethylarylenmethanols |
| US6121300A (en) | 1998-11-10 | 2000-09-19 | Wagle; Dilip R. | Reversing advanced glycosylation cross-links using heterocyclic-substituted thiazolium salts |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR244550A1 (es) * | 1978-07-24 | 1993-11-30 | Merck & Co Inc | Procedimiento para obtener una composicion de antibioticos del tipo de la tienamicina con inhibidores de la dipeptidasa |
| US4376774A (en) * | 1979-05-29 | 1983-03-15 | Merck & Co., Inc. | Antibiotic N-heterocyclyl thienamycin |
| NZ201471A (en) * | 1981-08-10 | 1985-09-13 | Merck & Co Inc | Antibacterial compositions containing penems and dipeptidase inhibitors |
| ZA836966B (en) * | 1982-09-28 | 1984-04-25 | Bristol Myers Co | Carbapenem antibiotics |
| NZ205626A (en) * | 1982-09-28 | 1986-12-05 | Bristol Myers Co | Carbapenem antibiotics |
-
1985
- 1985-06-26 CA CA000485383A patent/CA1273012A/en not_active Expired - Fee Related
- 1985-07-01 ES ES544751A patent/ES8609336A1/es not_active Expired
- 1985-07-01 EP EP85108132A patent/EP0170073A1/de not_active Withdrawn
- 1985-07-01 DK DK297585A patent/DK297585A/da not_active Application Discontinuation
- 1985-07-02 JP JP60145659A patent/JPS6183183A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA1273012A (en) | 1990-08-21 |
| ES544751A0 (es) | 1986-09-01 |
| EP0170073A1 (de) | 1986-02-05 |
| JPS6183183A (ja) | 1986-04-26 |
| DK297585D0 (da) | 1985-07-01 |
| ES8609336A1 (es) | 1986-09-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK297585A (da) | 1-methylcarbapenemer med externt alkylerede mono- eller bicycliske kvaternaere heteroarylalkylthio 2-substituenter samt laegemiddel indeholdende saadanne forbindelser | |
| GB2171404B (en) | Spiroxazine compounds and photochromic composition containing the same | |
| GB2102289B (en) | Dentifrice containing fluorine compounds and calcium and phosphate compounds | |
| DK164851C (da) | N-phenylmethylenalkadienamider med analgetisk virkning samt farmaceutiske praeparater indeholdende samme | |
| PH21267A (en) | Aryl hydroxamates useful as antiallergy agents | |
| DK150986D0 (da) | Hydroxamater med lipoxygenase-inhiberende virkning og terapeutiske midler indeholdende saadanne forbindelser | |
| DK297685A (da) | 1-methylcarbapenemer med kvaternaere heteroarylalkylthio 2-substituenter samt laegemiddel indeholdende saadanne forbindelser | |
| DK164852C (da) | N-phenylmethylenalkanamider med analgetisk virkning samt farmaceutiske praeparater indeholdende samme | |
| PT79562A (en) | Bicyclic heterocyclyl containing n-(bicyclic heterocyclyl)-4-piperidinamines | |
| GB2155914B (en) | Treatment of technetium containing solns | |
| ZA849331B (en) | Bicyclic heterocyclyl containing n-(bicyclic heterocyclyl)-4-piperidinamines | |
| DK311884D0 (da) | Calcitoninforbindelse samt fremstilling og anvendelse deraf | |
| EP0166436A3 (en) | Use of dolichol or its ester in medicines | |
| FI834770A0 (fi) | Ljuskaensligt blandkondensat samt med hjaelp av detta framstaelld ljuskaensligt kopiematerial | |
| DK419084D0 (da) | 2-aminomethyl-2-penem-forbindelser samt deres fremstilling og anvendelse | |
| GB8718630D0 (en) | Preventing fogging of surfaces | |
| PH20528A (en) | 4-substituted-2-azetidinone compounds and medicaments containing the compounds | |
| HUT36996A (en) | Herbicide prepates of sinergism effect | |
| DK407188A (da) | Substituerede bicyclooctaner | |
| FR2561792B1 (fr) | Box audiovisuel | |
| DK613984D0 (da) | 2-heterocyclyl-6-hydroxylavalkyl-2-penem-forbindelser samt deres fremstilling og anvendelse | |
| IL74946A0 (en) | Organophosphorus compounds and pharmaceutical compositions containing the same | |
| AT387374B (de) | Obenentnahmefraese | |
| SE8306928D0 (sv) | Kents kassett | |
| ES537504A0 (es) | Procedimiento de preparacion de imidazolinonas substituidas con arilo en posicion 2 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |