DK291381A - Mercaptoacyl-derivater af forskellige 4-substituerede proliner samt fremgangsmaade til fremstilling heraf - Google Patents
Mercaptoacyl-derivater af forskellige 4-substituerede proliner samt fremgangsmaade til fremstilling herafInfo
- Publication number
- DK291381A DK291381A DK291381A DK291381A DK291381A DK 291381 A DK291381 A DK 291381A DK 291381 A DK291381 A DK 291381A DK 291381 A DK291381 A DK 291381A DK 291381 A DK291381 A DK 291381A
- Authority
- DK
- Denmark
- Prior art keywords
- procedures
- preparing
- various
- substituted prolines
- mercaptoacyl derivatives
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 150000003148 prolines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
- C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5435—Cycloaliphatic phosphonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5456—Arylalkanephosphonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/164,985 US4316905A (en) | 1980-07-01 | 1980-07-01 | Mercaptoacyl derivatives of various 4-substituted prolines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK291381A true DK291381A (da) | 1982-01-02 |
Family
ID=22596924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK291381A DK291381A (da) | 1980-07-01 | 1981-06-30 | Mercaptoacyl-derivater af forskellige 4-substituerede proliner samt fremgangsmaade til fremstilling heraf |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4316905A (da) |
| JP (2) | JPS5745155A (da) |
| AT (1) | AT374453B (da) |
| AU (1) | AU543386B2 (da) |
| BE (1) | BE889444A (da) |
| CA (1) | CA1173834A (da) |
| CH (1) | CH651548A5 (da) |
| DE (1) | DE3125744A1 (da) |
| DK (1) | DK291381A (da) |
| FR (2) | FR2491468B1 (da) |
| GB (1) | GB2078733B (da) |
| IE (1) | IE51305B1 (da) |
| IT (1) | IT1137271B (da) |
| NL (1) | NL8103099A (da) |
| SE (1) | SE8104092L (da) |
| ZA (1) | ZA813401B (da) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5348944A (en) * | 1980-10-23 | 1994-09-20 | Schering Corporation | Carboxyalkyl dipeptides |
| US4374131A (en) * | 1981-04-27 | 1983-02-15 | E. R. Squibb & Sons, Inc. | Amino and substituted amino phosphinyl-alkanoyl compounds |
| US4416833A (en) * | 1981-05-04 | 1983-11-22 | E. R. Squibb & Sons, Inc. | Substituted carbonyl phosphinyl-alkanoyl compounds |
| US4381297A (en) * | 1981-05-04 | 1983-04-26 | E. R. Squibb & Sons, Inc. | Substituted carbonyl phosphinyl-alkanoyl compounds |
| US4432971A (en) * | 1981-08-03 | 1984-02-21 | E. R. Squibb & Sons, Inc. | Phosphonamidate compounds |
| US4555506A (en) * | 1981-12-24 | 1985-11-26 | E. R. Squibb & Sons, Inc. | Phosphorus containing compounds and use as hypotensives |
| US4560680A (en) * | 1982-03-15 | 1985-12-24 | E. R. Squibb & Sons, Inc. | Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors |
| US4452791A (en) * | 1982-03-15 | 1984-06-05 | E. R. Squibb & Sons, Inc. | Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors |
| US4448772A (en) * | 1982-04-22 | 1984-05-15 | E. R. Squibb & Sons, Inc. | Phosphinylmethylaminocarbonyl imino acid compounds useful for treating hypertension |
| US4560681A (en) * | 1982-04-22 | 1985-12-24 | E. R. Squibb & Sons, Inc. | Phosphinylmethylaminocarbonyl imino acid compounds useful for treating hypertension |
| CA1258853A (en) * | 1982-04-30 | 1989-08-29 | Rudiger D. Haugwitz | Substituted 4-phenoxy prolines |
| US4468519A (en) * | 1982-06-14 | 1984-08-28 | E. R. Squibb & Sons, Inc. | Esters of phosphinylalkanoyl substituted prolines |
| US4470973A (en) * | 1982-07-19 | 1984-09-11 | E. R. Squibb & Sons, Inc. | Substituted peptide compounds |
| US4621092A (en) * | 1982-07-22 | 1986-11-04 | E. R. Squibb & Sons, Inc. | Substituted proline compounds, composition and method of use |
| US4742067A (en) * | 1982-07-22 | 1988-05-03 | E. R. Squibb & Sons, Inc. | Acylalkylaminocarbonyl substituted amino and imino acid compounds |
| US4623729A (en) | 1982-07-22 | 1986-11-18 | E. R. Squibb & Sons, Inc. | Acylalkylaminocarbonyl substituted amino and imino acid compounds |
| US4404282A (en) * | 1982-08-19 | 1983-09-13 | Eli Lilly And Company | Process for enzyme inhibitor |
| US4508901A (en) * | 1982-08-19 | 1985-04-02 | Eli Lilly And Company | Quiuolizine and indolizine enzyme inhibitors |
| EP0103403B1 (en) * | 1982-08-19 | 1990-02-28 | Eli Lilly And Company | Enzyme inhibitors |
| US4404281A (en) * | 1982-08-19 | 1983-09-13 | Eli Lilly And Company | Process for enzyme inhibitors |
| US4524212A (en) * | 1982-09-27 | 1985-06-18 | E. R. Squibb & Sons, Inc. | Acyloxyketone substituted imino and amino acids |
| US4499079A (en) * | 1982-11-18 | 1985-02-12 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides |
| US4456595A (en) * | 1982-12-06 | 1984-06-26 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy aroly peptides |
| US4826812A (en) * | 1982-12-27 | 1989-05-02 | Schering Corporation | Antiglaucoma agent |
| US4514391A (en) * | 1983-07-21 | 1985-04-30 | E. R. Squibb & Sons, Inc. | Hydroxy substituted peptide compounds |
| US4594431A (en) * | 1983-08-01 | 1986-06-10 | Eli Lilly Company | Octahydroindolizinepropanoic acids and related compounds as enzyme inhibitors |
| US4675408A (en) * | 1983-08-01 | 1987-06-23 | Eli Lilly And Company | Octahydroindolizinepropanoic acids and related compounds as enzyme inhibitors |
| US4501901A (en) * | 1983-09-19 | 1985-02-26 | E. R. Squibb & Sons, Inc. | Method for making substituted prolines |
| US4602092A (en) * | 1983-09-19 | 1986-07-22 | E. R. Squibb & Sons, Inc. | Method for making phosphinic acid intermediates |
| US4594199A (en) * | 1983-09-19 | 1986-06-10 | E. R. Squibb & Sons, Inc. | Method for making phosphinic acid intermediates |
| EP0187037A3 (en) * | 1984-12-21 | 1988-03-23 | Takeda Chemical Industries, Ltd. | Piperidine derivatives, their production and use |
| US4649147A (en) * | 1985-07-08 | 1987-03-10 | G. D. Searle & Co. | Treating elastin degradation with 1-(alkenoyl)azacycloalkyl carboxylic acids and derivatives |
| US4851514A (en) * | 1987-05-01 | 1989-07-25 | E. R. Squibb & Sons, Inc. | Process for preparing a compound useful in preparing ace inhibitors and intermediate produced thereby |
| DE3814663C2 (de) * | 1987-05-01 | 1999-12-02 | Squibb & Sons Inc | Triphenyler, Verfahren zu seiner Herstellung sowie dessen Verwendung |
| US4937355A (en) * | 1989-01-17 | 1990-06-26 | E. R. Squibb & Sons, Inc. | Process for preparing (trans)-4-substituted-dl-proline derivatives |
| AU632596B2 (en) * | 1989-08-21 | 1993-01-07 | E.R. Squibb & Sons, Inc. | Phosphonate substituted amino or imino acids useful as antihypertensives |
| US7659305B2 (en) * | 2002-10-31 | 2010-02-09 | Pfizer Inc. | Therapeutic proline derivatives |
| SE0302381D0 (sv) * | 2003-09-04 | 2003-09-04 | Astrazeneca Ab | New salts I |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3485819A (en) * | 1968-07-02 | 1969-12-23 | Squibb & Sons Inc | Alpha-amino-cyclohexadienylalkylene-penicillins and cephalosporins |
| US3946000A (en) * | 1973-10-31 | 1976-03-23 | Bristol-Myers Company | 7-[α-(2-Aminomethyl-1-cyclohexenyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids |
| US4105776A (en) * | 1976-06-21 | 1978-08-08 | E. R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
| US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
| US4116962A (en) * | 1976-12-03 | 1978-09-26 | E. R. Squibb & Sons, Inc. | Pyrrolidine and piperidine-2-carboxylic acid derivatives |
| US4108886A (en) * | 1977-03-11 | 1978-08-22 | E. R. Squibb & Sons, Inc. | Thiopropanoylamino acid derivatives |
| US4154935A (en) * | 1978-02-21 | 1979-05-15 | E. R. Squibb & Sons, Inc. | Halogen substituted mercaptoacylamino acids |
| CA1109475A (en) * | 1978-07-27 | 1981-09-22 | Miguel A. Ondetti | Thiopropanoylamino acid derivatives |
| JPS584711B2 (ja) * | 1978-08-02 | 1983-01-27 | 参天製薬株式会社 | ピロリジン誘導体 |
| CA1144930A (en) * | 1978-08-11 | 1983-04-19 | Miguel A. Ondetti | Mercaptoacyl derivatives of substituted prolines |
| NL7809120A (nl) * | 1978-09-07 | 1980-03-11 | Oce Andeno B V Grubbenvorsterw | Werkwijze voor de bereiding van proline-derivaten. |
| CA1132985A (en) * | 1978-12-22 | 1982-10-05 | John Krapcho | Ketal and thioketal derivatives of mercaptoacyl prolines |
| CA1138452A (en) * | 1979-01-15 | 1982-12-28 | John Krapcho | Carbamate derivatives of mercaptoacyl hydroxy prolines |
-
1980
- 1980-07-01 US US06/164,985 patent/US4316905A/en not_active Expired - Lifetime
-
1981
- 1981-05-12 CA CA000377402A patent/CA1173834A/en not_active Expired
- 1981-05-15 AU AU70621/81A patent/AU543386B2/en not_active Ceased
- 1981-05-20 ZA ZA00813401A patent/ZA813401B/xx unknown
- 1981-06-11 GB GB8117920A patent/GB2078733B/en not_active Expired
- 1981-06-15 FR FR8111769A patent/FR2491468B1/fr not_active Expired
- 1981-06-16 IE IE1330/81A patent/IE51305B1/en not_active IP Right Cessation
- 1981-06-26 NL NL8103099A patent/NL8103099A/nl not_active Application Discontinuation
- 1981-06-29 AT AT0288981A patent/AT374453B/de not_active IP Right Cessation
- 1981-06-29 CH CH4276/81A patent/CH651548A5/fr not_active IP Right Cessation
- 1981-06-30 DE DE3125744A patent/DE3125744A1/de not_active Ceased
- 1981-06-30 SE SE8104092A patent/SE8104092L/xx not_active Application Discontinuation
- 1981-06-30 BE BE0/205261A patent/BE889444A/fr not_active IP Right Cessation
- 1981-06-30 DK DK291381A patent/DK291381A/da not_active Application Discontinuation
- 1981-06-30 JP JP56103886A patent/JPS5745155A/ja active Granted
- 1981-07-01 IT IT22675/81A patent/IT1137271B/it active
- 1981-10-22 FR FR8119835A patent/FR2491063A1/fr active Granted
-
1989
- 1989-12-26 JP JP1338035A patent/JPH02191250A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IE811330L (en) | 1982-01-01 |
| CH651548A5 (fr) | 1985-09-30 |
| FR2491468B1 (fr) | 1985-08-02 |
| FR2491063A1 (fr) | 1982-04-02 |
| AT374453B (de) | 1984-04-25 |
| GB2078733A (en) | 1982-01-13 |
| AU7062181A (en) | 1982-01-07 |
| IE51305B1 (en) | 1986-11-26 |
| JPH0233028B2 (da) | 1990-07-25 |
| GB2078733B (en) | 1984-05-02 |
| US4316905A (en) | 1982-02-23 |
| IT1137271B (it) | 1986-09-03 |
| ATA288981A (de) | 1983-09-15 |
| AU543386B2 (en) | 1985-04-18 |
| FR2491063B1 (da) | 1984-12-14 |
| JPH02191250A (ja) | 1990-07-27 |
| BE889444A (fr) | 1981-12-30 |
| FR2491468A1 (fr) | 1982-04-09 |
| JPS5745155A (en) | 1982-03-13 |
| IT8122675A0 (it) | 1981-07-01 |
| DE3125744A1 (de) | 1982-03-04 |
| SE8104092L (sv) | 1982-01-02 |
| NL8103099A (nl) | 1982-02-01 |
| ZA813401B (en) | 1982-06-30 |
| CA1173834A (en) | 1984-09-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK291381A (da) | Mercaptoacyl-derivater af forskellige 4-substituerede proliner samt fremgangsmaade til fremstilling heraf | |
| DK335879A (da) | Fremgangsmaade til fremstilling af mercaptoacylderivater af substituerede proliner | |
| DK534481A (da) | Fremgangsmaade til fremstilling af 1-sulfo-2-oxoazetidinderivater | |
| DK99781A (da) | Fremgangsmaade til fremstilling af carboxtyrilderivater | |
| DK435181A (da) | Fremgangsmaade til fremstilling af thiazol-derivater | |
| DK300981A (da) | Fremgangsmaade til fremstilling af imidazolderivater | |
| DK157876C (da) | Analogifremgangsmaade til fremstilling af imidazo-rifamycin-derivater | |
| DK519481A (da) | Carboxylkylaminosyrederivater af substituerede proliner fremgangsmaade til fremstilling heraf samt deres anvendelse som laegemidler | |
| DK161581A (da) | Fremgangsmaade til fremstilling af imidazolderivater | |
| DK417981A (da) | Fremgangsmaade til fremstilling af 3-aryl-5-isothiazol-derivater | |
| DK162524C (da) | Analogifremgangsmaade til fremstilling af 5-alkylthio-tetrazolderivater | |
| DK100281A (da) | Fremgangsmaade til fremstilling af imidazolderivater | |
| DK364181A (da) | Fremgangsmaade til fremstilling af caprolactamderivater | |
| NO810351L (no) | G imidazolinderivater og fremgangsmaate til deres fremstillin | |
| DK30781A (da) | Fremgangsmaade til fremstilling af triazolidinderivater | |
| DK147795C (da) | Analogifremgangsmaade til fremstilling af xanthinderivater | |
| DK564781A (da) | Fremgangsmaade til fremstilling af pyrazoloindazolderivater | |
| DK554581A (da) | Fremgangsmaade til fremstilling af alkylendioxybenzenderivater | |
| DK500081A (da) | Fremgangsmaade til fremstilling af glutaminderivater | |
| DK579878A (da) | Fremgangsmaade til acylering af 6-aminopenam og 7-aminocephemderivater | |
| DK151956C (da) | Analogifremgangsmaade til fremstilling af carbostyrilderivater | |
| DK381581A (da) | Fremgangsmaade til fremstilling af heterocycliske derivater | |
| DK424781A (da) | Fremgangsmaade til fremstilling af quinolonderivater | |
| DK148680A (da) | Fremgangsmaade til fremstilling af xanthinderivater | |
| DK255279A (da) | Piperidinderivater af 1,3,5-triazoxycloheptan-2,4-dion samt fremgangsmaade til fremstilling og anvendelse af disse |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |