DK2877494T3 - PTPRS og proteoglycaner i autoimmun sygdom - Google Patents
PTPRS og proteoglycaner i autoimmun sygdom Download PDFInfo
- Publication number
- DK2877494T3 DK2877494T3 DK13823022.2T DK13823022T DK2877494T3 DK 2877494 T3 DK2877494 T3 DK 2877494T3 DK 13823022 T DK13823022 T DK 13823022T DK 2877494 T3 DK2877494 T3 DK 2877494T3
- Authority
- DK
- Denmark
- Prior art keywords
- ptprs
- proteoglycans
- autoimmune disease
- autoimmune
- disease
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
- C12Y301/03048—Protein-tyrosine-phosphatase (3.1.3.48)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261674853P | 2012-07-23 | 2012-07-23 | |
US201261675036P | 2012-07-24 | 2012-07-24 | |
US201361832688P | 2013-06-07 | 2013-06-07 | |
PCT/US2013/051723 WO2014018554A1 (en) | 2012-07-23 | 2013-07-23 | Ptprs and proteoglycans in autoimmune disease |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2877494T3 true DK2877494T3 (da) | 2020-09-21 |
Family
ID=49997782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK13823022.2T DK2877494T3 (da) | 2012-07-23 | 2013-07-23 | PTPRS og proteoglycaner i autoimmun sygdom |
Country Status (5)
Country | Link |
---|---|
US (2) | US20150175979A1 (da) |
EP (1) | EP2877494B1 (da) |
DK (1) | DK2877494T3 (da) |
ES (1) | ES2817897T3 (da) |
WO (1) | WO2014018554A1 (da) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
CA3012985A1 (en) | 2015-01-27 | 2016-08-04 | Kardiatonos, Inc. | Biomarkers of vascular disease |
US20190160146A1 (en) * | 2016-05-12 | 2019-05-30 | Ohio State Innovation Foundation | Peptides and methods for treating neurodegenerative disorders |
WO2018176019A1 (en) | 2017-03-24 | 2018-09-27 | The Regents Of The University Of California | Proteoglycan irregularities in abnormal fibroblasts and therapies based therefrom |
CN113015746A (zh) * | 2018-09-19 | 2021-06-22 | 拉荷亚免疫研究所 | 在类风湿性关节炎中的ptprs和蛋白聚糖 |
CA3225321A1 (en) * | 2021-07-30 | 2023-02-02 | Nunzio Bottini | Ptprs in autoimmunity |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2413974A1 (fr) | 1978-01-06 | 1979-08-03 | David Bernard | Sechoir pour feuilles imprimees par serigraphie |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
US5235033A (en) | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
DE3689123T2 (de) | 1985-11-01 | 1994-03-03 | Xoma Corp | Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung. |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
EP0739904A1 (en) | 1989-06-29 | 1996-10-30 | Medarex, Inc. | Bispecific reagents for aids therapy |
US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
DK0814159T3 (da) | 1990-08-29 | 2005-10-24 | Genpharm Int | Transgene, ikke-humane dyr, der er i stand til at danne heterologe antistoffer |
WO1992020373A1 (en) | 1991-05-14 | 1992-11-26 | Repligen Corporation | Heteroconjugate antibodies for treatment of hiv infection |
WO1993008829A1 (en) | 1991-11-04 | 1993-05-13 | The Regents Of The University Of California | Compositions that mediate killing of hiv-infected cells |
US5777085A (en) | 1991-12-20 | 1998-07-07 | Protein Design Labs, Inc. | Humanized antibodies reactive with GPIIB/IIIA |
US6210671B1 (en) | 1992-12-01 | 2001-04-03 | Protein Design Labs, Inc. | Humanized antibodies reactive with L-selectin |
US5830645A (en) | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
AR013269A1 (es) | 1997-08-04 | 2000-12-13 | Scras | Producto que contiene por lo menos un rna de doble filamento combinado con por lo menos un agente anti-viral, para la utilizacion terapeutica en eltratamiento de una enfermedad viral, en especial de la hepatitis viral |
US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
GB9827152D0 (en) | 1998-07-03 | 1999-02-03 | Devgen Nv | Characterisation of gene function using double stranded rna inhibition |
WO2000032634A1 (en) | 1998-12-01 | 2000-06-08 | Protein Design Labs, Inc. | Humanized antibodies to gamma-interferon |
AU776150B2 (en) | 1999-01-28 | 2004-08-26 | Medical College Of Georgia Research Institute, Inc. | Composition and method for (in vivo) and (in vitro) attenuation of gene expression using double stranded RNA |
DE19956568A1 (de) | 1999-01-30 | 2000-08-17 | Roland Kreutzer | Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens |
AU1086501A (en) | 1999-10-15 | 2001-04-30 | Carnegie Institution Of Washington | Rna interference pathway genes as tools for targeted genetic interference |
GB9927444D0 (en) | 1999-11-19 | 2000-01-19 | Cancer Res Campaign Tech | Inhibiting gene expression |
JP2004532616A (ja) | 2000-12-28 | 2004-10-28 | ジョンソン・アンド・ジョンソン・リサーチ・ピー・ティー・ワイ・リミテッド | 二本鎖rna仲介遺伝子抑制 |
WO2007041317A2 (en) * | 2005-09-29 | 2007-04-12 | Viral Logic Systems Technology Corp. | Immunomodulatory compositions and uses therefor |
EP2531859A4 (en) * | 2010-02-02 | 2013-07-31 | Jolla Inst Allergy Immunolog | COMPOSITIONS AND METHOD FOR MODULATING RECEPTOR PROTEIN TYROSINE PHOSPHATASES |
BR112013027631A2 (pt) | 2011-04-28 | 2022-01-04 | Sbi Biotech Co Ltd | Método para a produção de anticorpo monoclonal ou fragmento que inclui uma região de ligação ao antígeno do mesmo, anticorpo monoclonal ou um fragmento que inclui uma região de 5 ligação ao antígeno do mesmo, hibridoma, método para a detecção de uma célula dendrítica plasmocitóide, uso de um anticorpo monoclonal ou um fragmento que inclui uma região de ligação ao antígeno do mesmo, e método ex vivo para suprimir a atividade de uma célula dendrítica plasmocitóide |
-
2013
- 2013-07-23 EP EP13823022.2A patent/EP2877494B1/en active Active
- 2013-07-23 DK DK13823022.2T patent/DK2877494T3/da active
- 2013-07-23 WO PCT/US2013/051723 patent/WO2014018554A1/en active Application Filing
- 2013-07-23 US US14/416,839 patent/US20150175979A1/en active Pending
- 2013-07-23 ES ES13823022T patent/ES2817897T3/es active Active
-
2022
- 2022-06-23 US US17/848,241 patent/US20220325261A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2014018554A1 (en) | 2014-01-30 |
EP2877494B1 (en) | 2020-07-15 |
US20150175979A1 (en) | 2015-06-25 |
EP2877494A1 (en) | 2015-06-03 |
EP2877494A4 (en) | 2016-04-20 |
ES2817897T3 (es) | 2021-04-08 |
US20220325261A1 (en) | 2022-10-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK2920313T3 (da) | Rekombinante adenovira og anvendelse deraf | |
DK2839860T3 (da) | Pyrrolobenzodiazepiner og konjugater deraf | |
DK3470086T3 (da) | Pyrrolobenzodiazepiner og konjugater deraf | |
DK2850202T3 (da) | Fremgangsmåder og grupper | |
DK2844282T3 (da) | Prostata-associerede antigener og vaccine-baserede immunterapiregimener | |
DK2838596T3 (da) | Intermitterende katetersamling | |
HK1206667A1 (en) | Extracellular matrix encasement structures and methods | |
DK2815483T3 (da) | Flerrumsatterioplader | |
BR302012004119S1 (pt) | Configuração aplicada em unidade de carga | |
BR302013000588S1 (pt) | Configuração aplicada em instrumento médico | |
BR112014000049A2 (pt) | pirrolotriazinas substituídas com hidroximelilarilo e sua utilização | |
BR112012029414A2 (pt) | arquiteturas ordenadas em polímeros acrílicos | |
DK3453723T3 (da) | Anti-ASIC1-antistoffer og anvendelser deraf | |
DK3326642T3 (da) | Langtidsvirkende koagulationsfaktorer og brugen deraf | |
DK2877494T3 (da) | PTPRS og proteoglycaner i autoimmun sygdom | |
BR302013000213S1 (pt) | Configuração aplicada em instrumento médico | |
BR302012006078S1 (pt) | Configuração aplicada em instrumento médico | |
FR3015775B1 (fr) | Butee de cosse de batterie et unite de cosse de batterie | |
DK2943460T3 (da) | 6-chlor-3-(phenyl-d5)-inden-1-on og anvendelse deraf | |
GB2511282B (en) | Improvements in or relating to hinge arrangements | |
BR112013013208A2 (pt) | bogie e sua estrutura lateral | |
DK2812435T3 (da) | Transskriptionsenheder og anvendelse heraf i ekspressionsvektorer | |
BR302013000215S1 (pt) | Configuração aplicada em instrumento médico | |
BR302012006533S1 (pt) | Configuração aplicada em bisnaga | |
BR302012006534S1 (pt) | Configuração aplicada em bisnaga |