DK284485A - Indol-2-alkansyre og farmaceutisk praeparat indeholdende en saadan forbindelse - Google Patents
Indol-2-alkansyre og farmaceutisk praeparat indeholdende en saadan forbindelse Download PDFInfo
- Publication number
- DK284485A DK284485A DK284485A DK284485A DK284485A DK 284485 A DK284485 A DK 284485A DK 284485 A DK284485 A DK 284485A DK 284485 A DK284485 A DK 284485A DK 284485 A DK284485 A DK 284485A
- Authority
- DK
- Denmark
- Prior art keywords
- indol
- relationship
- pharmaceutical preparation
- preparation containing
- alkanic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62417384A | 1984-06-25 | 1984-06-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
DK284485D0 DK284485D0 (da) | 1985-06-24 |
DK284485A true DK284485A (da) | 1986-02-24 |
Family
ID=24500964
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK284485A DK284485A (da) | 1984-06-25 | 1985-06-24 | Indol-2-alkansyre og farmaceutisk praeparat indeholdende en saadan forbindelse |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0166591B1 (fr) |
JP (1) | JPS6163653A (fr) |
KR (1) | KR860000258A (fr) |
AU (1) | AU4377685A (fr) |
CA (1) | CA1241660A (fr) |
DE (1) | DE3574372D1 (fr) |
DK (1) | DK284485A (fr) |
ES (1) | ES8609245A1 (fr) |
GR (1) | GR851494B (fr) |
IL (1) | IL75586A (fr) |
PT (1) | PT80698B (fr) |
ZA (1) | ZA854762B (fr) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2543952B1 (fr) * | 1982-09-03 | 1986-02-21 | Bristol Myers Co | Composes hydrocarbones heterocycliques appartenant aux series indoliques et leur application pharmacologique |
GB8607294D0 (en) * | 1985-04-17 | 1986-04-30 | Ici America Inc | Heterocyclic amide derivatives |
US5179112A (en) * | 1985-04-17 | 1993-01-12 | Ici Americas Inc. | Heterocyclic amide derivatives and pharmaceutical use |
US4837235A (en) * | 1985-10-17 | 1989-06-06 | Ici Americas Inc. | Indole and indazole keto sulphones as leukotriene antagonists |
GB8623429D0 (en) * | 1985-10-17 | 1986-11-05 | Ici America Inc | Carboximide derivatives |
GB8707051D0 (en) * | 1986-04-15 | 1987-04-29 | Ici America Inc | Heterocyclic carboxamides |
GB8609175D0 (en) * | 1986-04-15 | 1986-05-21 | Ici America Inc | Heterocyclic carboxamides |
NZ222878A (en) * | 1986-12-17 | 1991-02-26 | Merck Frosst Canada Inc | 3-hetero-substituted-n-benzyl-indole derivatives, and pharmaceutical compositions |
US5081138A (en) * | 1986-12-17 | 1992-01-14 | Merck Frosst Canada, Inc. | 3-hetero-substituted-n-benzyl-indoles and prevention of leucotriene synthesis therewith |
EP0300675A3 (fr) * | 1987-07-21 | 1990-04-11 | Merck Frosst Canada Inc. | Méthode pour l'amélioration des traitements par la cyclosporine |
DE3807922A1 (de) * | 1988-03-10 | 1989-09-21 | Boehringer Mannheim Gmbh | Substituierte heterocyclen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
IT1227362B (it) * | 1988-11-18 | 1991-04-08 | Istituto Biochimico Italiano | Derivati indolici, processo per la loro preparazione e loro uso comefarmaci antitrombotici |
US5093351A (en) * | 1989-01-05 | 1992-03-03 | Du Pont Merck Pharmaceutical Company | Substituted indole, benzofuran and benzothiophene derivatives as 5-lipoxygenase inhibitors |
NZ234883A (en) * | 1989-08-22 | 1995-01-27 | Merck Frosst Canada Inc | Quinolin-2-ylmethoxy indole derivatives, preparation and pharmaceutical compositions thereof |
US5204344A (en) * | 1989-08-22 | 1993-04-20 | Merck Frosst Canada, Inc. | (Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes |
US5272145A (en) * | 1989-08-22 | 1993-12-21 | Merck Frosst Canada, Inc. | (Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes |
GB9108811D0 (en) * | 1991-04-24 | 1991-06-12 | Erba Carlo Spa | N-imidazolyl derivatives of substituted indole |
CA2079374C (fr) * | 1991-09-30 | 2003-08-05 | Merck Frosst Canada Incorporated | Indol (azaarylmethoxy bicyclique) comme inhibiteur de leucotriene biosynthetique |
US5190968A (en) * | 1991-09-30 | 1993-03-02 | Merck Frosst Canada, Inc. | (Polycyclic-arylmethoxy) indoles as inhibitors of leukotriene biosynthesis |
US5290798A (en) * | 1991-09-30 | 1994-03-01 | Merck Frosst Canada, Inc. | (hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis |
US5308850A (en) * | 1991-09-30 | 1994-05-03 | Merck Frosst Canada, Inc. | (Bicyclic-hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis |
US5389650A (en) * | 1991-09-30 | 1995-02-14 | Merck Frosst Canada, Inc. | (Azaarylmethoxy)indoles as inhibitors of leukotriene biosynthesis |
CA2129429A1 (fr) * | 1992-02-13 | 1993-08-14 | Richard Frenette | (azaaromaticalkoxy) indoles utilises comme inhibiteurs de la biosynthese de la leucotriene |
US5374635A (en) * | 1993-03-29 | 1994-12-20 | Merck Frosst Canada, Inc. | Furo[3,2-b]pyridines and thieno[3,2-b]pyridines as inhibitors of leukotriene biosynthesis |
DE122009000061I1 (de) * | 1996-04-19 | 2009-12-31 | Wyeth N D Ges D Staates Delawa | Östrogene Verbindungen |
US6069153A (en) * | 1998-05-12 | 2000-05-30 | American Home Products Corporation | Indenoindoles and benzocarbazoles as estrogenic agents |
US6479535B1 (en) | 1998-05-15 | 2002-11-12 | Wyeth | 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations |
GB9902461D0 (en) * | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
US6159959A (en) * | 1999-05-06 | 2000-12-12 | American Home Products Corporation | Combined estrogen and antiestrogen therapy |
JP4279561B2 (ja) * | 2001-05-23 | 2009-06-17 | メルク フロスト カナダ リミテツド | プロスタグランジンD2受容体拮抗薬としてのジヒドロピロロ[1,2−a]インドールおよびテトラヒドロピリド[1,2−a]−インドール誘導体 |
ATE479686T1 (de) | 2002-10-30 | 2010-09-15 | Merck Frosst Canada Ltd | Pyridopyrrolizin- und pyridoindolizinderivate |
EA200701504A1 (ru) | 2005-01-19 | 2008-02-28 | Биолипокс Аб | Индолы, пригодные для лечения воспалений |
WO2007121578A1 (fr) * | 2006-04-24 | 2007-11-01 | Merck Frosst Canada Ltd. | Dérivés d'indolamide comme antagonistes du récepteur ep4 |
WO2020003119A1 (fr) * | 2018-06-25 | 2020-01-02 | Suzhou Mednes Pharma Tech Co., Ltd. | Composés et méthodes pour le traitement d'affections associées à la voie hedgehog |
CN109535060B (zh) * | 2018-12-20 | 2022-03-25 | 苏州麦迪耐斯医药科技有限公司 | 一种刺猬通路抑制剂及其制备方法和应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH454858A (de) * | 1965-05-13 | 1968-04-30 | Geigy Ag J R | Verfahren zur Herstellung von neuen Indolderivaten |
CH455777A (de) * | 1965-05-13 | 1968-05-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen Indolderivaten |
-
1985
- 1985-06-17 CA CA000484174A patent/CA1241660A/fr not_active Expired
- 1985-06-18 AU AU43776/85A patent/AU4377685A/en not_active Abandoned
- 1985-06-19 GR GR851494A patent/GR851494B/el unknown
- 1985-06-20 IL IL75586A patent/IL75586A/xx unknown
- 1985-06-24 DE DE8585304468T patent/DE3574372D1/de not_active Expired
- 1985-06-24 KR KR1019850004471A patent/KR860000258A/ko not_active Application Discontinuation
- 1985-06-24 EP EP85304468A patent/EP0166591B1/fr not_active Expired
- 1985-06-24 DK DK284485A patent/DK284485A/da not_active Application Discontinuation
- 1985-06-24 PT PT80698A patent/PT80698B/pt unknown
- 1985-06-25 JP JP60137091A patent/JPS6163653A/ja active Pending
- 1985-06-25 ES ES544524A patent/ES8609245A1/es not_active Expired
- 1985-06-25 ZA ZA854762A patent/ZA854762B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
ZA854762B (en) | 1986-02-26 |
JPS6163653A (ja) | 1986-04-01 |
DE3574372D1 (en) | 1989-12-28 |
EP0166591A3 (en) | 1986-06-25 |
IL75586A0 (en) | 1985-10-31 |
DK284485D0 (da) | 1985-06-24 |
EP0166591A2 (fr) | 1986-01-02 |
EP0166591B1 (fr) | 1989-11-23 |
AU4377685A (en) | 1986-01-02 |
CA1241660A (fr) | 1988-09-06 |
ES8609245A1 (es) | 1986-09-01 |
ES544524A0 (es) | 1986-09-01 |
GR851494B (fr) | 1985-11-25 |
PT80698A (en) | 1985-07-01 |
KR860000258A (ko) | 1986-01-27 |
PT80698B (en) | 1987-03-31 |
IL75586A (en) | 1988-09-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |