CA2129429A1 - (azaaromaticalkoxy) indoles utilises comme inhibiteurs de la biosynthese de la leucotriene - Google Patents

(azaaromaticalkoxy) indoles utilises comme inhibiteurs de la biosynthese de la leucotriene

Info

Publication number
CA2129429A1
CA2129429A1 CA002129429A CA2129429A CA2129429A1 CA 2129429 A1 CA2129429 A1 CA 2129429A1 CA 002129429 A CA002129429 A CA 002129429A CA 2129429 A CA2129429 A CA 2129429A CA 2129429 A1 CA2129429 A1 CA 2129429A1
Authority
CA
Canada
Prior art keywords
compound
hydrogen
pharmaceutically acceptable
formula
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002129429A
Other languages
English (en)
Inventor
Richard Frenette
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Frosst Canada and Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2129429A1 publication Critical patent/CA2129429A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002129429A 1992-02-13 1993-02-12 (azaaromaticalkoxy) indoles utilises comme inhibiteurs de la biosynthese de la leucotriene Abandoned CA2129429A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83491892A 1992-02-13 1992-02-13
US834,918 1992-02-13

Publications (1)

Publication Number Publication Date
CA2129429A1 true CA2129429A1 (fr) 1993-08-14

Family

ID=25268134

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002129429A Abandoned CA2129429A1 (fr) 1992-02-13 1993-02-12 (azaaromaticalkoxy) indoles utilises comme inhibiteurs de la biosynthese de la leucotriene

Country Status (3)

Country Link
AU (1) AU3488693A (fr)
CA (1) CA2129429A1 (fr)
WO (1) WO1993016069A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG72827A1 (en) * 1997-06-23 2000-05-23 Hoffmann La Roche Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives
GB9716657D0 (en) 1997-08-07 1997-10-15 Zeneca Ltd Chemical compounds
GB9803226D0 (en) 1998-02-17 1998-04-08 Zeneca Ltd Chemical compounds
EP1143972A4 (fr) * 1998-10-13 2004-07-28 Fred D Sheftell Prevention et traitement de migraines et autres cephalees recurrentes au moyen de medicaments inhibant le recepteur de leucotriene d4
GB9902455D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902453D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902461D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902452D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902459D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB0000625D0 (en) 2000-01-13 2000-03-01 Zeneca Ltd Chemical compounds
US20070219206A1 (en) * 2005-11-04 2007-09-20 Amira Pharmaceuticals, Inc. 5-lipoxygenase-activating protein (flap) inhibitors
GB2431927B (en) * 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
US20070244128A1 (en) * 2005-11-04 2007-10-18 Amira Pharmaceuticals, Inc. 5-lipoxygenase-activating protein (flap) inhibitors
US20070225285A1 (en) * 2005-11-04 2007-09-27 Amira Pharmaceuticals, Inc. 5-lipoxygenase-activating protein (flap) inhibitors
US7645752B2 (en) 2006-01-13 2010-01-12 Wyeth Llc Sulfonyl substituted 1H-indoles as ligands for the 5-hydroxytryptamine receptors
AU2007316736A1 (en) 2006-11-09 2008-05-15 F. Hoffmann-La Roche Ag Indole and benzofuran 2-carboxamide derivatives
CA2938879C (fr) 2014-02-04 2023-05-09 Bioscience Pharma Partners, Llc Utilisation d'inhibiteurs de flap pour reduire une lesion mediee par une neuro-inflammation dans le systeme nerveux central

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1241660A (fr) * 1984-06-25 1988-09-06 Yvan Guindon Acides indole-2-alkanoique
NO174506B (no) * 1984-10-30 1994-02-07 Usv Pharma Corp Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser
NZ234883A (en) * 1989-08-22 1995-01-27 Merck Frosst Canada Inc Quinolin-2-ylmethoxy indole derivatives, preparation and pharmaceutical compositions thereof
PT95692A (pt) * 1989-10-27 1991-09-13 American Home Prod Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase
US5095031A (en) * 1990-08-20 1992-03-10 Abbott Laboratories Indole derivatives which inhibit leukotriene biosynthesis

Also Published As

Publication number Publication date
WO1993016069A1 (fr) 1993-08-19
AU3488693A (en) 1993-09-03

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead