CA2136241C - Indoles a base de quinoleines fluores en tant qu'inhibiteurs de la biosynthese de leucotrienes - Google Patents
Indoles a base de quinoleines fluores en tant qu'inhibiteurs de la biosynthese de leucotrienes Download PDFInfo
- Publication number
- CA2136241C CA2136241C CA002136241A CA2136241A CA2136241C CA 2136241 C CA2136241 C CA 2136241C CA 002136241 A CA002136241 A CA 002136241A CA 2136241 A CA2136241 A CA 2136241A CA 2136241 C CA2136241 C CA 2136241C
- Authority
- CA
- Canada
- Prior art keywords
- compound
- formula
- pharmaceutically acceptable
- medicament
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/903,051 US5252585A (en) | 1992-02-03 | 1992-06-22 | Fluorinated quinoline indoles as inhibitors of the biosynthesis of leukotrienes |
US903,051 | 1992-06-22 | ||
PCT/CA1993/000256 WO1994000446A1 (fr) | 1992-06-22 | 1993-06-17 | Quinoleine indoles fluores utilises comme inhibiteurs de la biosynthese de leucotrienes |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2136241A1 CA2136241A1 (fr) | 1994-01-06 |
CA2136241C true CA2136241C (fr) | 2004-01-27 |
Family
ID=25416859
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002136241A Expired - Fee Related CA2136241C (fr) | 1992-06-22 | 1993-06-17 | Indoles a base de quinoleines fluores en tant qu'inhibiteurs de la biosynthese de leucotrienes |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU4413893A (fr) |
CA (1) | CA2136241C (fr) |
WO (1) | WO1994000446A1 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8399666B2 (en) | 2005-11-04 | 2013-03-19 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
US7977359B2 (en) | 2005-11-04 | 2011-07-12 | Amira Pharmaceuticals, Inc. | 5-lipdxygenase-activating protein (FLAP) inhibitors |
GB2431927B (en) | 2005-11-04 | 2010-03-17 | Amira Pharmaceuticals Inc | 5-Lipoxygenase-activating protein (FLAP) inhibitors |
EP2114876A4 (fr) * | 2007-02-05 | 2010-12-22 | Amira Pharmaceuticals Inc | Indoles inverses en tant qu'inhibiteurs de la protéine d'activation de la 5-lipoxygénase (flap) |
WO2008103866A1 (fr) * | 2007-02-22 | 2008-08-28 | Microbia, Inc. | Synthèse d'indoles |
KR20160129109A (ko) | 2008-05-23 | 2016-11-08 | 아미라 파마슈티칼스 인코포레이티드 | 5-리폭시게나아제 활성화 단백질 억제제 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE59889B1 (en) * | 1986-02-14 | 1994-04-20 | Merck Frosst Canada Inc | 2-substituted quinoline dioic acids |
NZ234883A (en) * | 1989-08-22 | 1995-01-27 | Merck Frosst Canada Inc | Quinolin-2-ylmethoxy indole derivatives, preparation and pharmaceutical compositions thereof |
US5095031A (en) * | 1990-08-20 | 1992-03-10 | Abbott Laboratories | Indole derivatives which inhibit leukotriene biosynthesis |
-
1993
- 1993-06-17 WO PCT/CA1993/000256 patent/WO1994000446A1/fr active Application Filing
- 1993-06-17 CA CA002136241A patent/CA2136241C/fr not_active Expired - Fee Related
- 1993-06-17 AU AU44138/93A patent/AU4413893A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU4413893A (en) | 1994-01-24 |
WO1994000446A1 (fr) | 1994-01-06 |
CA2136241A1 (fr) | 1994-01-06 |
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CA2136241C (fr) | Indoles a base de quinoleines fluores en tant qu'inhibiteurs de la biosynthese de leucotrienes | |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |