DK27486A - Beta-lactamforbindelse - Google Patents

Beta-lactamforbindelse Download PDF

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Publication number
DK27486A
DK27486A DK27486A DK27486A DK27486A DK 27486 A DK27486 A DK 27486A DK 27486 A DK27486 A DK 27486A DK 27486 A DK27486 A DK 27486A DK 27486 A DK27486 A DK 27486A
Authority
DK
Denmark
Prior art keywords
beta
lactam compound
lactam
compound
Prior art date
Application number
DK27486A
Other languages
Danish (da)
English (en)
Other versions
DK27486D0 (da
Inventor
Shigeo Shimizu
Hiroyuki Takano
Fujio Yagihashi
Original Assignee
Sankei Yakuhin Kk
Nippon Pharma Dev Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankei Yakuhin Kk, Nippon Pharma Dev Inst filed Critical Sankei Yakuhin Kk
Publication of DK27486D0 publication Critical patent/DK27486D0/da
Publication of DK27486A publication Critical patent/DK27486A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK27486A 1985-01-21 1986-01-20 Beta-lactamforbindelse DK27486A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP858785 1985-01-21
JP1198685 1985-01-25

Publications (2)

Publication Number Publication Date
DK27486D0 DK27486D0 (da) 1986-01-20
DK27486A true DK27486A (da) 1986-07-22

Family

ID=26343130

Family Applications (1)

Application Number Title Priority Date Filing Date
DK27486A DK27486A (da) 1985-01-21 1986-01-20 Beta-lactamforbindelse

Country Status (13)

Country Link
US (1) US4808711A (hu)
EP (1) EP0189287B1 (hu)
JP (1) JPS61267583A (hu)
KR (1) KR930007417B1 (hu)
AU (1) AU586215B2 (hu)
CA (1) CA1277977C (hu)
DE (1) DE3687279T2 (hu)
DK (1) DK27486A (hu)
ES (1) ES8706159A1 (hu)
HU (1) HU202538B (hu)
IL (1) IL77676A (hu)
NZ (1) NZ214864A (hu)
PH (1) PH22882A (hu)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE150507T1 (de) * 1983-12-29 1987-02-26 Mochida Pharmaceutical Co., Ltd., Tokio/Tokyo Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
EP0210815A3 (en) * 1985-07-25 1988-04-20 Beecham Group Plc 6-beta-(alpha-etherified oxyimino)-acylamino penicillanic-acid derivatives, their preparation and use
ZA874696B (en) * 1986-07-03 1988-01-04 F. Hoffmann-La Roche & Co. Aktiengesellschaft Acyl derivatives
US5147871A (en) * 1986-07-03 1992-09-15 Hoffmann La-Roche, Inc. Anti-bacterial cephalosporin compounds
FI872879A (fi) * 1986-07-21 1988-01-22 Sankei Yakuhin Kk --laktamfoerening, foerfarande foer dess framstaellning, denna innehaollande laekemedelskomposition foer behandling av sjukdom med bakterieinfektion samt mellanprodukter foer dess syntes.
AT392969B (de) * 1986-11-17 1991-07-25 Sankei Yakuhin Kk Beta-lactamverbindungen, verfahren zu ihrer herstellung, dieselben enthaltende pharmazeutischepraeparate zur behandlung von durch bakterien verursachte infektionskrankheiten
DK170088A (da) * 1987-04-10 1988-10-11 Hoffmann La Roche Acylderivater
MC1921A1 (fr) * 1987-04-10 1989-04-06 Sankei Yakuhin Kk Derives acyles
FI883320A (fi) * 1987-08-07 1989-02-08 Sankei Yakuhin Kk --laktam, dess framstaellning och mellanprodukter foer dess framstaellning.
US5073550A (en) * 1987-08-14 1991-12-17 Hoffmann-La Roche Inc. Cephalosphorins with sulfur-containing oxyimino side chain
EP0303172A3 (de) * 1987-08-14 1991-05-15 F. Hoffmann-La Roche Ag Oxyimino-Cephalosporine
US5138066A (en) * 1987-08-14 1992-08-11 Hoffmann-La Roche, Inc. Intermediates for cephalosporins with sulfur-containing oxyimino side chain
CS273349B2 (en) * 1988-03-31 1991-03-12 Hoffmann La Roche Method of cephalosporin's new derivatives production
US5336768A (en) * 1988-05-24 1994-08-09 Hoffmann-La Roche Inc. Antibacterial cephalosporin compounds
US5159077A (en) * 1989-07-21 1992-10-27 Hoffmann-La Roche Inc. Penam antibacterial compounds
US5162523A (en) * 1989-07-21 1992-11-10 Hoffmann-La Roche Inc. Cephalosporin antibacterial compounds
EP0492277A3 (en) * 1990-12-20 1992-10-14 F. Hoffmann-La Roche Ag Cephalosporin derivatives
EP0550775A1 (en) * 1992-01-07 1993-07-14 F. Hoffmann-La Roche Ag Cephalosporin derivatives
US5318781A (en) * 1993-04-06 1994-06-07 Hoffmann-La Roche Inc. Absorption enhancement of antibiotics
US5599988A (en) * 1994-12-22 1997-02-04 Smithkline Beecham Corporation Large scale preparation of 2,4-dihydroxybenzaldehyde using a variation of the Vilsmeierhaack reaction and isolated intermediates
DE19654920A1 (de) * 1996-06-26 1998-01-08 Gruenenthal Gmbh Neue synthetische Catecholderivate, Verfahren zu ihrer Herstellung und ihre Verwendung
US20130065874A1 (en) 2011-09-09 2013-03-14 Cubist Pharmaceuticals, Inc. Methods for treating intrapulmonary infections
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
KR102226197B1 (ko) 2013-03-15 2021-03-11 머크 샤프 앤드 돔 코포레이션 세프톨로잔 항균성 조성물
US20140274991A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
AU2014233637A1 (en) 2013-09-09 2015-03-26 Merck Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1476312A (en) * 1974-06-03 1977-06-10 Beecham Group Ltd Penicillins and cephalosporins
US4091212A (en) * 1976-11-26 1978-05-23 E. R. Squibb & Sons, Inc. Hydrazinocarbonylamino cephalosporins 3-heterocyclicthio 7-hydrazinocarbonylamino acetylamino cephalosporins
JPS609719B2 (ja) * 1977-08-06 1985-03-12 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
DE150507T1 (de) * 1983-12-29 1987-02-26 Mochida Pharmaceutical Co., Ltd., Tokio/Tokyo Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.

Also Published As

Publication number Publication date
DE3687279T2 (de) 1993-05-13
DK27486D0 (da) 1986-01-20
HU202538B (en) 1991-03-28
PH22882A (en) 1989-01-19
EP0189287A3 (en) 1987-09-30
EP0189287B1 (en) 1992-12-16
DE3687279D1 (de) 1993-01-28
ES8706159A1 (es) 1987-06-01
HUT41800A (en) 1987-05-28
ES551071A0 (es) 1987-06-01
EP0189287A2 (en) 1986-07-30
KR930007417B1 (ko) 1993-08-10
NZ214864A (en) 1988-04-29
AU5244986A (en) 1986-07-24
AU586215B2 (en) 1989-07-06
KR860005824A (ko) 1986-08-13
JPS61267583A (ja) 1986-11-27
US4808711A (en) 1989-02-28
IL77676A (en) 1990-09-17
CA1277977C (en) 1990-12-18

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment