DK477186A - Indolobenzodiazepinforbindelser - Google Patents

Indolobenzodiazepinforbindelser Download PDF

Info

Publication number
DK477186A
DK477186A DK477186A DK477186A DK477186A DK 477186 A DK477186 A DK 477186A DK 477186 A DK477186 A DK 477186A DK 477186 A DK477186 A DK 477186A DK 477186 A DK477186 A DK 477186A
Authority
DK
Denmark
Prior art keywords
indolobenzodiazepin
compounds
indolobenzodiazepin compounds
Prior art date
Application number
DK477186A
Other languages
English (en)
Other versions
DK477186D0 (da
Inventor
Chih Yung Ho
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of DK477186D0 publication Critical patent/DK477186D0/da
Publication of DK477186A publication Critical patent/DK477186A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK477186A 1985-10-07 1986-10-06 Indolobenzodiazepinforbindelser DK477186A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/784,963 US4678784A (en) 1984-04-11 1985-10-07 Method for the treatment of LHRH diseases and conditions

Publications (2)

Publication Number Publication Date
DK477186D0 DK477186D0 (da) 1986-10-06
DK477186A true DK477186A (da) 1987-04-08

Family

ID=25134067

Family Applications (1)

Application Number Title Priority Date Filing Date
DK477186A DK477186A (da) 1985-10-07 1986-10-06 Indolobenzodiazepinforbindelser

Country Status (5)

Country Link
US (1) US4678784A (da)
EP (1) EP0219292A2 (da)
JP (1) JPS62116514A (da)
AU (1) AU6362386A (da)
DK (1) DK477186A (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1072219C (zh) * 1995-06-01 2001-10-03 武田药品工业株式会社 二氮杂䓬酮、其生产和用途
US5780437A (en) * 1995-12-14 1998-07-14 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US5756507A (en) * 1995-12-14 1998-05-26 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US5849764A (en) * 1995-12-14 1998-12-15 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
NZ325060A (en) * 1995-12-14 2000-02-28 Merck & Co Inc Non peptide indole derivative and their use as antagonists of gonadotropin releasing hormone
US6200957B1 (en) 1995-12-14 2001-03-13 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6162813A (en) * 1996-05-20 2000-12-19 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6147088A (en) * 1996-05-20 2000-11-14 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
EP0901489A1 (en) * 1996-05-20 1999-03-17 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6150522A (en) * 1996-05-20 2000-11-21 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6156767A (en) * 1997-06-05 2000-12-05 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6004984A (en) * 1997-06-05 1999-12-21 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6156772A (en) * 1997-06-05 2000-12-05 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US5981550A (en) * 1997-06-05 1999-11-09 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US5985901A (en) * 1997-06-05 1999-11-16 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6620824B2 (en) 2001-04-11 2003-09-16 Merck & Co., Inc. Process for the synthesis of gonadotropin releasing hormone antagonists
WO2007095495A2 (en) * 2006-02-13 2007-08-23 Pharmacopeia, Inc. Benzodiazepine gcnf modulators for stem cell modulation
CN105175434A (zh) 2009-02-05 2015-12-23 伊缪诺金公司 新型苯并二氮杂*衍生物
EP3498303A1 (en) 2011-02-15 2019-06-19 ImmunoGen, Inc. Methods of preparation of conjugates
IL283355B (en) 2015-07-21 2022-08-01 Immunogen Inc Methods for the preparation of cytotoxic benzodiazepine compounds
CN110437236B (zh) * 2019-08-28 2020-08-18 青岛农业大学 一种吲哚-1,2-并1,4-苯并二氮杂卓类化合物及其合成方法

Also Published As

Publication number Publication date
AU6362386A (en) 1987-04-09
JPS62116514A (ja) 1987-05-28
US4678784A (en) 1987-07-07
DK477186D0 (da) 1986-10-06
EP0219292A2 (en) 1987-04-22

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment