DK2734255T5 - Auto-injector for returnable pre-filled syringe - Google Patents
Auto-injector for returnable pre-filled syringe Download PDFInfo
- Publication number
- DK2734255T5 DK2734255T5 DK12766198.1T DK12766198T DK2734255T5 DK 2734255 T5 DK2734255 T5 DK 2734255T5 DK 12766198 T DK12766198 T DK 12766198T DK 2734255 T5 DK2734255 T5 DK 2734255T5
- Authority
- DK
- Denmark
- Prior art keywords
- actuating
- housing
- needle
- actuation
- pill
- Prior art date
Links
- 229940090047 auto-injector Drugs 0.000 title description 4
- 229940071643 prefilled syringe Drugs 0.000 title description 4
- 239000006187 pill Substances 0.000 claims description 109
- 230000007246 mechanism Effects 0.000 claims description 106
- 230000004913 activation Effects 0.000 claims description 61
- 238000000034 method Methods 0.000 claims description 25
- 230000003213 activating effect Effects 0.000 claims description 5
- 239000008188 pellet Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 description 28
- 229940079593 drug Drugs 0.000 description 23
- 239000007924 injection Substances 0.000 description 20
- 238000002347 injection Methods 0.000 description 20
- 239000012530 fluid Substances 0.000 description 11
- 239000007788 liquid Substances 0.000 description 9
- 239000004033 plastic Substances 0.000 description 9
- 229920003023 plastic Polymers 0.000 description 9
- 238000012377 drug delivery Methods 0.000 description 8
- 238000013519 translation Methods 0.000 description 7
- 238000003780 insertion Methods 0.000 description 6
- 230000037431 insertion Effects 0.000 description 6
- 230000009471 action Effects 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 239000007787 solid Substances 0.000 description 5
- 239000000853 adhesive Substances 0.000 description 4
- 230000001070 adhesive effect Effects 0.000 description 4
- POIUWJQBRNEFGX-XAMSXPGMSA-N cathelicidin Chemical compound C([C@@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(O)=O)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C)C1=CC=CC=C1 POIUWJQBRNEFGX-XAMSXPGMSA-N 0.000 description 4
- -1 for example Polymers 0.000 description 4
- 239000011521 glass Substances 0.000 description 4
- 239000003292 glue Substances 0.000 description 4
- 230000033001 locomotion Effects 0.000 description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- 230000006837 decompression Effects 0.000 description 3
- 230000000994 depressogenic effect Effects 0.000 description 3
- 229920001971 elastomer Polymers 0.000 description 3
- 230000003993 interaction Effects 0.000 description 3
- 230000014759 maintenance of location Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000000717 retained effect Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 229920001169 thermoplastic Polymers 0.000 description 3
- 229920001187 thermosetting polymer Polymers 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 239000000806 elastomer Substances 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 239000004634 thermosetting polymer Substances 0.000 description 2
- 239000004925 Acrylic resin Substances 0.000 description 1
- 229920000178 Acrylic resin Polymers 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 206010069803 Injury associated with device Diseases 0.000 description 1
- 208000012266 Needlestick injury Diseases 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000013536 elastomeric material Substances 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- ZUBZATZOEPUUQF-UHFFFAOYSA-N isopropylhexane Natural products CCCCCCC(C)C ZUBZATZOEPUUQF-UHFFFAOYSA-N 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 238000012961 medicinal therapy Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000012744 reinforcing agent Substances 0.000 description 1
- 239000010421 standard material Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- OIWCYIUQAVBPGV-DAQGAKHBSA-N {1-O-hexadecanoyl-2-O-[(Z)-octadec-9-enoyl]-sn-glycero-3-phospho}serine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC OIWCYIUQAVBPGV-DAQGAKHBSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/322—Retractable needles, i.e. disconnected from and withdrawn into the syringe barrel by the piston
- A61M5/3234—Fully automatic needle retraction, i.e. in which triggering of the needle does not require a deliberate action by the user
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2026—Semi-automatic, e.g. user activated piston is assisted by additional source of energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/322—Retractable needles, i.e. disconnected from and withdrawn into the syringe barrel by the piston
- A61M5/3221—Constructional features thereof, e.g. to improve manipulation or functioning
- A61M2005/3231—Proximal end of needle captured or embedded inside piston head, e.g. by friction or hooks
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/0318—Processes
- Y10T137/0402—Cleaning, repairing, or assembling
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Environmental & Geological Engineering (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161526995P | 2011-08-24 | 2011-08-24 | |
| PCT/US2012/052129 WO2013028906A1 (en) | 2011-08-24 | 2012-08-23 | Auto-injector for retractable prefilled syringe |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK2734255T3 DK2734255T3 (en) | 2016-08-01 |
| DK2734255T5 true DK2734255T5 (en) | 2016-10-10 |
Family
ID=46934669
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12766198.1T DK2734255T5 (en) | 2011-08-24 | 2012-08-23 | Auto-injector for returnable pre-filled syringe |
| DK14193283.0T DK2837396T3 (en) | 2011-08-24 | 2012-08-23 | Auto-injector for returnable pre-filled syringe |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14193283.0T DK2837396T3 (en) | 2011-08-24 | 2012-08-23 | Auto-injector for returnable pre-filled syringe |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8808244B2 (enExample) |
| EP (2) | EP2734255B1 (enExample) |
| JP (1) | JP6141846B2 (enExample) |
| CN (1) | CN103747824B (enExample) |
| AU (1) | AU2012298793B2 (enExample) |
| BR (1) | BR112014004103A2 (enExample) |
| CA (1) | CA2845362C (enExample) |
| DK (2) | DK2734255T5 (enExample) |
| ES (2) | ES2572510T3 (enExample) |
| IL (2) | IL230973B (enExample) |
| PT (2) | PT2837396E (enExample) |
| TW (1) | TWI608853B (enExample) |
| WO (1) | WO2013028906A1 (enExample) |
Families Citing this family (85)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0307589A (pt) | 2002-02-11 | 2005-02-01 | Antares Pharma Inc | Dispositivo de injeção intradérmica |
| EP3495009B2 (en) | 2005-01-24 | 2025-01-15 | Antares Pharma, Inc. | An injector with prefilled syringe |
| US8361026B2 (en) | 2005-02-01 | 2013-01-29 | Intelliject, Inc. | Apparatus and methods for self-administration of vaccines and other medicaments |
| WO2007131025A1 (en) | 2006-05-03 | 2007-11-15 | Antares Pharma, Inc. | Injector with adjustable dosing |
| US8251947B2 (en) | 2006-05-03 | 2012-08-28 | Antares Pharma, Inc. | Two-stage reconstituting injector |
| JP5731829B2 (ja) | 2008-03-10 | 2015-06-10 | アンタレス・ファーマ・インコーポレーテッド | 注射器安全装置 |
| AU2009279719B2 (en) | 2008-08-05 | 2015-07-23 | Antares Pharma, Inc. | Multiple dosage injector |
| US12097357B2 (en) | 2008-09-15 | 2024-09-24 | West Pharma. Services IL, Ltd. | Stabilized pen injector |
| ES2988196T3 (es) | 2009-03-20 | 2024-11-19 | Antares Pharma Inc | Sistema de inyección de agentes peligrosos |
| MX2012007116A (es) * | 2009-12-22 | 2012-12-17 | Unitract Syringe Pty Ltd | Jeringa retractil con eficiencia de suministro mejorada y sistema de bloqueo. |
| US9173999B2 (en) | 2011-01-26 | 2015-11-03 | Kaleo, Inc. | Devices and methods for delivering medicaments from a multi-chamber container |
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| US8939943B2 (en) | 2011-01-26 | 2015-01-27 | Kaleo, Inc. | Medicament delivery device for administration of opioid antagonists including formulations for naloxone |
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| CA2842077C (en) | 2011-08-05 | 2019-09-03 | Unitract Syringe Pty Ltd | Dual chamber mixing device for a syringe |
| JP6141846B2 (ja) | 2011-08-24 | 2017-06-14 | ユニトラクト シリンジ プロプライエタリイ リミテッドＵｎｉｔｒａｃｔ Ｓｙｒｉｎｇｅ Ｐｔｙ Ｌｔｄ | 引き込み可能なプレフィルドシリンジのためのオート注入器 |
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| BR112014005272B1 (pt) | 2011-09-09 | 2021-01-19 | Merck Patent Gmbh | autoinjetor recarregável para injeção de adrenalina |
| US8992476B2 (en) | 2011-09-22 | 2015-03-31 | Abbvie Inc. | Automatic injection device |
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| ES2606933T3 (es) | 2012-02-06 | 2017-03-28 | Unitract Syringe Pty Ltd | Subconjuntos de émbolo y autoinyectores que tienen fuerza de activación de retracción baja |
| PT2822618T (pt) | 2012-03-06 | 2024-03-04 | Antares Pharma Inc | Seringa pré-cheia com característica de força de rutura |
| US9950125B2 (en) | 2012-04-06 | 2018-04-24 | Antares Pharma, Inc. | Needle assisted jet injection administration of testosterone compositions |
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| PT2925391T (pt) | 2012-11-30 | 2017-08-10 | Unitract Syringe Pty Ltd | Dispositivo de combinação de êmbolos para uma seringa de mistura com duas câmaras |
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- 2012-08-23 JP JP2014527311A patent/JP6141846B2/ja not_active Expired - Fee Related
- 2012-08-23 US US13/593,293 patent/US8808244B2/en active Active
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- 2012-08-23 CA CA2845362A patent/CA2845362C/en not_active Expired - Fee Related
- 2012-08-23 DK DK12766198.1T patent/DK2734255T5/en active
- 2012-08-23 ES ES12766198T patent/ES2572510T3/es active Active
- 2012-08-23 EP EP12766198.1A patent/EP2734255B1/en not_active Not-in-force
- 2012-08-23 AU AU2012298793A patent/AU2012298793B2/en not_active Ceased
- 2012-08-23 ES ES14193283.0T patent/ES2572578T3/es active Active
- 2012-08-23 PT PT141932830T patent/PT2837396E/pt unknown
- 2012-08-23 PT PT127661981T patent/PT2734255T/pt unknown
- 2012-08-23 EP EP14193283.0A patent/EP2837396B1/en not_active Not-in-force
- 2012-08-23 BR BR112014004103A patent/BR112014004103A2/pt not_active Application Discontinuation
- 2012-08-23 WO PCT/US2012/052129 patent/WO2013028906A1/en not_active Ceased
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- 2012-08-24 TW TW101130775A patent/TWI608853B/zh not_active IP Right Cessation
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| AU2012298793A1 (en) | 2014-03-06 |
| CA2845362A1 (en) | 2013-02-28 |
| EP2837396A1 (en) | 2015-02-18 |
| PT2734255T (pt) | 2016-07-15 |
| PT2837396E (pt) | 2016-06-20 |
| CN103747824A (zh) | 2014-04-23 |
| TWI608853B (zh) | 2017-12-21 |
| BR112014004103A2 (pt) | 2017-04-04 |
| AU2012298793B2 (en) | 2016-07-07 |
| DK2734255T3 (en) | 2016-08-01 |
| EP2734255B1 (en) | 2016-04-27 |
| IL230973A0 (en) | 2014-03-31 |
| CA2845362C (en) | 2020-05-05 |
| JP6141846B2 (ja) | 2017-06-14 |
| EP2734255A1 (en) | 2014-05-28 |
| US20130060231A1 (en) | 2013-03-07 |
| ES2572510T3 (es) | 2016-05-31 |
| JP2014524345A (ja) | 2014-09-22 |
| TW201315499A (zh) | 2013-04-16 |
| IL257043A (en) | 2018-03-29 |
| IL230973B (en) | 2018-08-30 |
| US10166336B2 (en) | 2019-01-01 |
| US20140323982A1 (en) | 2014-10-30 |
| EP2837396B1 (en) | 2016-05-11 |
| ES2572578T3 (es) | 2016-06-01 |
| IL257043B (en) | 2019-05-30 |
| CN103747824B (zh) | 2016-08-17 |
| US8808244B2 (en) | 2014-08-19 |
| WO2013028906A1 (en) | 2013-02-28 |
| DK2837396T3 (en) | 2016-08-22 |
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