DK2731967T3 - HUMAN BINDING MOLECULES CAPABLE OF NEUTRALIZING INFLUENZA A VIRUS FROM PHYLOGENETIC GROUP 1 AND PHYLOGENETIC GROUP 2 AND INFLUENZA B VIRUS - Google Patents
HUMAN BINDING MOLECULES CAPABLE OF NEUTRALIZING INFLUENZA A VIRUS FROM PHYLOGENETIC GROUP 1 AND PHYLOGENETIC GROUP 2 AND INFLUENZA B VIRUS Download PDFInfo
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- DK2731967T3 DK2731967T3 DK12735516.2T DK12735516T DK2731967T3 DK 2731967 T3 DK2731967 T3 DK 2731967T3 DK 12735516 T DK12735516 T DK 12735516T DK 2731967 T3 DK2731967 T3 DK 2731967T3
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- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
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- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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Landscapes
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| PCT/EP2012/063637 WO2013007770A1 (en) | 2011-07-14 | 2012-07-12 | Human binding molecules capable of neutralizing influenza a viruses of phylogenetic group 1 and phylogenetic group 2 and influenza b viruses |
Publications (1)
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| DK2731967T3 true DK2731967T3 (en) | 2017-01-16 |
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| US8961978B2 (en) | 2011-07-14 | 2015-02-24 | Crucell Holland B.V. | Human binding molecules capable of neutralizing influenza A viruses of phylogenetic group 1 and phylogenetic group 2 and influenza B viruses |
| WO2013079473A1 (en) | 2011-11-28 | 2013-06-06 | Crucell Holland B.V. | Influenza virus vaccines and uses thereof |
| CN104302321A (zh) | 2011-12-05 | 2015-01-21 | 特瑞利斯生物科学有限责任公司 | 可用于被动流感免疫的抗体 |
| US9969794B2 (en) | 2012-05-10 | 2018-05-15 | Visterra, Inc. | HA binding agents |
| CA2906676A1 (en) * | 2013-03-14 | 2014-09-25 | Contrafect Corporation | Composition and methods based on neutralizing antibodies delivered intranasally for enhanced therapeutic efficacy |
| US9649375B2 (en) | 2013-03-14 | 2017-05-16 | The Administrators Of The Tulane Educational Fund | Immunogenic peptide conjugate and method for inducing an anti-influenza therapeutic antibody response therewith |
| KR20140118682A (ko) * | 2013-03-29 | 2014-10-08 | (주)셀트리온 | 2 이상의 인플루엔자 ａ 바이러스 중화 결합 분자를 포함하는 조성물 |
| BR112015029635B1 (pt) | 2013-05-30 | 2023-05-02 | Janssen Vaccines & Prevention B.V | Polipeptídeo do domínio de haste da hemaglutinina da gripe e composição |
| LT3052192T (lt) * | 2013-10-02 | 2020-12-10 | Medimmune, Llc | Neutralizuojantys antikūnai prieš gripą a ir jų naudojimas |
| RU2682049C2 (ru) * | 2014-01-27 | 2019-03-14 | Дженентек, Инк. | Лечение вируса гриппа а h7n9 |
| US10639370B2 (en) | 2014-02-04 | 2020-05-05 | Contrafect Corporation | Antibodies useful in passive influenza immunization, and compositions, combinations and methods for use thereof |
| JP6712428B2 (ja) * | 2014-02-04 | 2020-06-24 | コントラフェクト コーポレイション | インフルエンザ受動免疫に有用な抗体ならびにその使用のための組成物、組合せおよび方法 |
| BR112016018313A8 (pt) | 2014-02-10 | 2018-06-12 | Igm Biosciences Inc | Moléculas de ligação multiespecíficas iga |
| BR112016022113A2 (pt) * | 2014-03-27 | 2017-10-31 | Genentech Inc | anticorpos anti-hemaglutinina do vírus influenza b e métodos de uso |
| KR101628331B1 (ko) * | 2014-03-28 | 2016-06-08 | 주식회사 녹십자엠에스 | 인플루엔자 a 바이러스 특이적 단클론 항체 및 이를 이용한 인플루엔자 감염 치료 및 진단 방법 |
| JP7094103B2 (ja) | 2014-07-10 | 2022-07-01 | ヤンセン ファッシンズ アンド プリベンション ベーフェー | インフルエンザウイルスワクチンおよびその使用 |
| EP3166962B1 (en) | 2014-07-10 | 2019-08-21 | Janssen Vaccines & Prevention B.V. | Influenza virus vaccines and uses thereof |
| AU2015289805B2 (en) * | 2014-07-15 | 2020-06-25 | Humabs Biomed Sa | Neutralizing anti-influenza B antibodies and uses thereof |
| TWI702229B (zh) | 2014-12-19 | 2020-08-21 | 美商再生元醫藥公司 | 流行性感冒病毒血球凝集素之人類抗體 |
| WO2016124682A1 (en) | 2015-02-05 | 2016-08-11 | Janssen Vaccines & Prevention B.V. | Human neutralizing antibodies binding to influenza neuraminidase |
| CA2975655C (en) * | 2015-02-05 | 2023-09-19 | Janssen Vaccines & Prevention B.V. | Binding molecules directed against influenza hemagglutinin and uses thereof |
| EP3280730B1 (en) * | 2015-04-08 | 2024-01-03 | Dana-Farber Cancer Institute, Inc. | Humanized influenza monoclonal antibodies and methods of use thereof |
| CA2985402A1 (en) | 2015-05-11 | 2016-11-17 | Janssen Vaccines & Prevention B.V. | Influenza virus neutralizing peptidomimetic compounds |
| US11535665B2 (en) | 2015-05-13 | 2022-12-27 | The Trustees Of The University Of Pennsylvania | AAV-mediated expression of anti-influenza antibodies and methods of use thereof |
| PL3303384T3 (pl) | 2015-06-01 | 2022-01-03 | Medimmune, Llc | Neutralizujące cząsteczki wiążące przeciw grypie i ich zastosowania |
| EP3374390A1 (en) | 2015-11-13 | 2018-09-19 | Visterra, Inc. | Compositions and methods for treating and preventing influenza |
| CA3010313A1 (en) | 2016-01-13 | 2017-07-20 | Medimmune, Llc | Method of treating influenza a |
| CA3015347A1 (en) | 2016-02-24 | 2017-08-31 | Visterra, Inc. | Formulations of antibody molecules to influenza virus |
| WO2017148889A1 (en) | 2016-03-01 | 2017-09-08 | Janssen Vaccines & Prevention B.V. | Human neutralizing antibodies binding to influenza b neuraminidase |
| WO2017192589A1 (en) * | 2016-05-02 | 2017-11-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Neutralizing antibodies to influenza ha and their use and identification |
| WO2018038096A1 (ja) * | 2016-08-23 | 2018-03-01 | 国立大学法人東京大学 | モノクローナル抗体又はその抗原結合フラグメント及びその使用 |
| AU2017350304B2 (en) | 2016-10-27 | 2022-03-03 | Janssen Vaccines & Prevention B.V. | Influenza virus neutralizing compounds |
| EP3574008B1 (en) * | 2017-01-27 | 2023-11-08 | National Research Council of Canada | Hemagglutinin-specific antibodies and uses thereof |
| US11040963B2 (en) | 2017-02-02 | 2021-06-22 | Janssen Vaccines & Prevention B.V. | Piperazine derivatives for influenza virus inhibitions |
| WO2018141854A1 (en) | 2017-02-02 | 2018-08-09 | Janssen Vaccines & Prevention B.V. | Piperazine derivatives for influenza virus inhibition |
| WO2018160573A1 (en) | 2017-02-28 | 2018-09-07 | The Trustees Of The University Of Pennsylvania | Influenza vaccines based on aav vectors |
| WO2018160582A1 (en) | 2017-02-28 | 2018-09-07 | The Trustees Of The University Of Pennsylvania | Adeno-associated virus (aav) clade f vector and uses therefor |
| JOP20190200A1 (ar) | 2017-02-28 | 2019-08-27 | Univ Pennsylvania | تركيبات نافعة في معالجة ضمور العضل النخاعي |
| SMT202200354T1 (it) | 2018-01-23 | 2022-09-14 | Janssen Vaccines & Prevention Bv | Vaccino per virus dell'influenza e suoi usi |
| JP7372925B2 (ja) | 2018-01-26 | 2023-11-01 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | インフルエンザヘマグルチニンに対するヒト抗体 |
| EP3946613A1 (en) | 2019-03-25 | 2022-02-09 | Visterra, Inc. | Compositions and methods for treating and preventing influenza |
| CA3152957A1 (en) * | 2019-09-05 | 2021-03-11 | Janssen Vaccines & Prevention B.V. | Influenza virus vaccines and uses thereof |
| WO2021173965A1 (en) | 2020-02-28 | 2021-09-02 | Massachusetts Institute Of Technology | Identification of variable influenza residues and uses thereof |
| WO2021201677A1 (en) | 2020-04-01 | 2021-10-07 | Kiadis Pharma Intellectual Property B.V. | Compositions and methods targeting influenza |
| US11175293B1 (en) | 2021-01-04 | 2021-11-16 | University Of Utah Research Foundation | Rapid assay for detection of SARS-CoV-2 antibodies |
| CN116761605A (zh) * | 2021-02-04 | 2023-09-15 | 四川海思科制药有限公司 | Ha抑制剂化合物的盐及晶型 |
| JP2025512515A (ja) | 2022-04-14 | 2025-04-17 | インビジシールド テクノロジーズ リミテッド | インフルエンザ感染症を予防又は治療するための組成物 |
| WO2024104947A2 (en) | 2022-11-14 | 2024-05-23 | Janssen Vaccines & Prevention B.V. | Influenza b virus vaccines and uses thereof |
| CN116589566A (zh) * | 2022-11-18 | 2023-08-15 | 昆明医科大学第一附属医院 | 一种HIV-1中和抗体的改造重组单克隆IgM抗体及其应用 |
| US20250090650A1 (en) | 2023-09-06 | 2025-03-20 | Sanofi | Modified influenza b hemagglutinin polypeptides and nucleic acids and uses thereof |
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| NZ207394A (en) | 1983-03-08 | 1987-03-06 | Commw Serum Lab Commission | Detecting or determining sequence of amino acids |
| NL9101953A (nl) | 1991-11-21 | 1993-06-16 | Seed Capital Investments | Testinrichting omvattende een plaat met een veelvoud van putjes met een bijbehorende doseerinrichting, alsmede een kit die deze inrichtingen omvat en toepassing van de inrichtingen. |
| US6265150B1 (en) | 1995-06-07 | 2001-07-24 | Becton Dickinson & Company | Phage antibodies |
| CA2267139A1 (en) | 1996-10-08 | 1998-04-16 | Ton Logtenberg | Methods and means for selecting peptides and proteins having specific affinity for a target |
| WO2000063403A2 (en) | 1999-04-15 | 2000-10-26 | Crucell Holland B.V. | Recombinant protein production in a human cell using sequences encoding adenovirus e1 protein |
| DK1402025T3 (da) | 2001-06-15 | 2006-06-06 | Crucell Holland Bv | Kimære fager |
| MY170607A (en) * | 2006-09-07 | 2019-08-20 | Crucell Holland Bv | Human binding molecules capable of neutralizing influenza virus h5n1 and uses thereof |
| FR2921928B1 (fr) * | 2007-10-08 | 2011-03-04 | Sanofi Pasteur | Anticorps monoclonaux specifiques de l'hemagglutinine du virus grippal |
| KR20110049802A (ko) | 2008-07-25 | 2011-05-12 | 인스티튜트 포 리서치 인 바이오메드슨 | 중화 항-인플루엔자 ａ 바이러스 항체 및 이의 용도 |
| EP2168987A1 (en) * | 2008-09-22 | 2010-03-31 | Mucosis B.V. | Multifunctional linker protein containing an antibody against hemagglutinin, a conserved influenza antigen and an immunostimulating carrier binding domain |
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- 2012-07-12 ES ES12735516.2T patent/ES2608321T3/es active Active
- 2012-07-12 BR BR112014000263-0A patent/BR112014000263B1/pt active IP Right Grant
- 2012-07-12 CA CA2838999A patent/CA2838999C/en active Active
- 2012-07-12 EP EP12735516.2A patent/EP2731967B1/en active Active
- 2012-07-12 KR KR1020137035132A patent/KR101941724B1/ko active Active
- 2012-07-12 HR HRP20161740TT patent/HRP20161740T1/hr unknown
- 2012-07-12 PH PH1/2013/502479A patent/PH12013502479A1/en unknown
- 2012-07-12 WO PCT/EP2012/063637 patent/WO2013007770A1/en not_active Ceased
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2013
- 2013-12-29 IL IL230222A patent/IL230222A/en active IP Right Grant
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2015
- 2015-01-14 US US14/597,016 patent/US9593159B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2608321T3 (es) | 2017-04-07 |
| PH12013502479A1 (en) | 2014-01-20 |
| AU2012282504B2 (en) | 2017-07-20 |
| US20140120113A1 (en) | 2014-05-01 |
| MY166282A (en) | 2018-06-25 |
| JP2014527403A (ja) | 2014-10-16 |
| CA2838999A1 (en) | 2013-01-17 |
| AU2012282504A1 (en) | 2014-02-06 |
| NZ618530A (en) | 2016-05-27 |
| KR20140095017A (ko) | 2014-07-31 |
| US20150274811A1 (en) | 2015-10-01 |
| US8961978B2 (en) | 2015-02-24 |
| KR101941724B1 (ko) | 2019-01-23 |
| IN2014CN00953A (enExample) | 2015-04-10 |
| BR112014000263B1 (pt) | 2022-01-18 |
| CN103906763A (zh) | 2014-07-02 |
| MX346206B (es) | 2017-03-09 |
| JP5683752B2 (ja) | 2015-03-11 |
| EP2731967A1 (en) | 2014-05-21 |
| EA201490288A1 (ru) | 2014-05-30 |
| IL230222A (en) | 2017-09-28 |
| EA027054B1 (ru) | 2017-06-30 |
| HRP20161740T1 (hr) | 2017-02-10 |
| MX2014000373A (es) | 2014-03-31 |
| CA2838999C (en) | 2021-02-16 |
| CN103906763B (zh) | 2016-10-12 |
| BR112014000263A2 (pt) | 2017-02-14 |
| EP2731967B1 (en) | 2016-10-12 |
| US9593159B2 (en) | 2017-03-14 |
| WO2013007770A1 (en) | 2013-01-17 |
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