DK2717926T3 - COMPOSITIONS AND PROCEDURES FOR PREVENTION AND TREATMENT OF BIOFILM - Google Patents

COMPOSITIONS AND PROCEDURES FOR PREVENTION AND TREATMENT OF BIOFILM Download PDF

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Publication number
DK2717926T3
DK2717926T3 DK12800279.7T DK12800279T DK2717926T3 DK 2717926 T3 DK2717926 T3 DK 2717926T3 DK 12800279 T DK12800279 T DK 12800279T DK 2717926 T3 DK2717926 T3 DK 2717926T3
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Denmark
Prior art keywords
biofilm
trehalase
vol
trehalose
biofilms
Prior art date
Application number
DK12800279.7T
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Danish (da)
English (en)
Inventor
Dennis W Davis
Brad W Arenz
Thomas K Connellan
Svetlana A Ivanova
Original Assignee
Ziolase Llc
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Publication of DK2717926T3 publication Critical patent/DK2717926T3/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01028Alpha,alpha-trehalase (3.2.1.28)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50Isolated enzymes; Isolated proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture
    • Y10T29/49826Assembling or joining

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Agronomy & Crop Science (AREA)
  • Oncology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Birds (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Pest Control & Pesticides (AREA)
  • Ophthalmology & Optometry (AREA)
DK12800279.7T 2011-06-13 2012-06-01 COMPOSITIONS AND PROCEDURES FOR PREVENTION AND TREATMENT OF BIOFILM DK2717926T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161520654P 2011-06-13 2011-06-13
US13/481,787 US20120315260A1 (en) 2011-06-13 2012-05-26 Compositions and Methods to Prevent and Treat Biofilms
PCT/US2012/040408 WO2012173796A2 (en) 2011-06-13 2012-06-01 Compositions and methods to prevent and treat biofilms

Publications (1)

Publication Number Publication Date
DK2717926T3 true DK2717926T3 (en) 2017-09-18

Family

ID=47293375

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12800279.7T DK2717926T3 (en) 2011-06-13 2012-06-01 COMPOSITIONS AND PROCEDURES FOR PREVENTION AND TREATMENT OF BIOFILM

Country Status (5)

Country Link
US (1) US20120315260A1 (https=)
EP (1) EP2717926B1 (https=)
JP (1) JP2015502179A (https=)
DK (1) DK2717926T3 (https=)
WO (1) WO2012173796A2 (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5548121B2 (ja) 2007-05-14 2014-07-16 リサーチ ファウンデーション オブ ステイト ユニバーシティ オブ ニューヨーク バイオフィルム中の細菌細胞における生理学的分散応答の誘導
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US10420822B2 (en) 2011-06-13 2019-09-24 Ziolase, Llc Compositions and methods to prevent and treat biofilms
US9549904B2 (en) 2012-06-06 2017-01-24 Thomas Bryan Method of destroying bacterial biofilm using sterile intravenous or intracavernous glycerin
US9480669B2 (en) 2015-01-06 2016-11-01 The Regents Of The University Of California Method of destroying and preventing bacterial and fungal biofilm by amino acid infusion
US9345573B2 (en) 2012-05-30 2016-05-24 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
DE102013201883B4 (de) * 2013-02-05 2025-11-20 Zyfoma Gmbh Verwendung einer wässrigen Lösung einer Säure als Behandlungsflüssigkeit zur Reinigung eines Implantat-Teils
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
EP2803372A1 (en) 2013-05-16 2014-11-19 Universiteit Twente Process for the preparation of an object supporting a lipid bilayer
US20180044628A1 (en) * 2015-03-13 2018-02-15 The Regents Of The University Of California Method for Biofilm Control and Treatment
JP6849658B2 (ja) * 2015-08-18 2021-03-24 ウィスコンシン アルムニ リサーチ ファンデイション 医療機器包装フィルムからのClO2ガスの放出
WO2017100927A1 (en) 2015-12-15 2017-06-22 Neovasc Tiara Inc. Transseptal delivery system
JP7006940B2 (ja) 2016-01-29 2022-01-24 ニオバスク ティアラ インコーポレイテッド 流出の閉塞を回避するための人工弁
JP7249149B2 (ja) * 2016-05-12 2023-03-30 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア バイオフィルムの堆積および産生を阻害するための組成物および方法
WO2018209345A1 (en) * 2017-05-12 2018-11-15 The Trustees Of The University Of Pennsylvania Compositions and methods for inhibiting biofilm deposition and production
WO2018090148A1 (en) 2016-11-21 2018-05-24 Neovasc Tiara Inc. Methods and systems for rapid retraction of a transcatheter heart valve delivery system
BR112019018738A2 (pt) * 2017-03-10 2020-04-07 Biohm Health Llc composições e métodos para promoção de uma flora microbiana saudável em um mamífero
US11382885B2 (en) 2017-06-07 2022-07-12 The Regents Of The University Of California Compositions for treating fungal and bacterial biofilms and methods of using the same
CN111263622A (zh) 2017-08-25 2020-06-09 内奥瓦斯克迪亚拉公司 顺序展开的经导管二尖瓣假体
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
AU2019374743B2 (en) 2018-11-08 2022-03-03 Neovasc Tiara Inc. Ventricular deployment of a transcatheter mitral valve prosthesis
US12226386B2 (en) 2018-12-03 2025-02-18 The Regents Of The University Of California Compositions and methods for treating biofilms
JP7430732B2 (ja) 2019-03-08 2024-02-13 ニオバスク ティアラ インコーポレイテッド 回収可能補綴物送達システム
EP3946163B1 (en) 2019-04-01 2025-08-20 Neovasc Tiara Inc. Controllably deployable prosthetic valve
US11491006B2 (en) 2019-04-10 2022-11-08 Neovasc Tiara Inc. Prosthetic valve with natural blood flow
EP4729110A2 (en) 2019-05-20 2026-04-22 Neovasc Tiara Inc. Introducer with hemostasis mechanism
WO2020257643A1 (en) 2019-06-20 2020-12-24 Neovasc Tiara Inc. Low profile prosthetic mitral valve
CN110538314B (zh) * 2019-09-28 2024-09-13 上海泌码生命科学有限公司 用于杀灭已形成生物膜的铜绿假单胞菌的抗菌肽组合物
CN113769148B (zh) * 2021-09-27 2023-03-21 中国科学院微生物研究所 PslG蛋白在隐形眼镜护理液中的应用
US12109176B1 (en) 2023-04-20 2024-10-08 Thomas Bryan Effect of glycerol on biofilm forming bacteria and fungi that changes the microbes sensitivity to pro and anti-biofilm non-toxic, non-bonded plasma amino acids and amino acid derivatives

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0751063A (ja) * 1993-06-11 1995-02-28 Kirin Brewery Co Ltd 逆反応性を有するトレハラーゼ、およびα,α−トレハロースの製造方法
JP3659985B2 (ja) * 1993-12-28 2005-06-15 三栄源エフ・エフ・アイ株式会社 トレハラーゼ及び該酵素を用いた糖類の製法
NZ306445A (en) * 1995-04-07 1999-02-25 Betzdearborn Inc Exopolysaccharide degrading enzyme and its use in the treatment of aqueous systems
AU2446997A (en) * 1996-04-10 1997-10-29 Merck & Co., Inc. Method for improving culture medium for recombinant yeasts
IN1997CH00924A (en) * 1996-05-03 2005-03-04 Syngenta Mogen Bv Regulating metabolism by modifying the level of trehalose-6-phosphate
US6759040B1 (en) * 1997-09-12 2004-07-06 University Of Maryland, College Park Preparation and use of biofilm-degrading, multiple-specificity, hydrolytic enzyme mixtures
US20020022005A1 (en) * 1997-10-16 2002-02-21 Budny John A. Compositions for treating cystic fibrosis
US5871714A (en) * 1997-10-16 1999-02-16 Pharmacal Biotechnologies, Inc. Compositions for controlling bacterial colonization
EP1068871A1 (en) * 1999-07-07 2001-01-17 Jean-Paul Perraudin Novel methods and medicament for treating infections diseases involving microbial biofilms
EP1081232A1 (en) * 1999-08-30 2001-03-07 K.U. Leuven Research & Development Novel target for antifungals
JP3959439B2 (ja) * 2001-08-21 2007-08-15 学校法人 東洋大学 耐熱性トレハラーゼと、その製造法
EP1796687A2 (en) * 2004-09-14 2007-06-20 Elixir Pharmaceuticals, Inc. Combination therapy for controlled carbohydrate digestion
US20080139450A1 (en) * 2005-07-01 2008-06-12 Srinivasa Madhyastha Antimicrobial Compositions and Uses Thereof
EP1872791A1 (en) * 2006-06-30 2008-01-02 Institut Pasteur Use of bacterial polysaccharides for biofilm inhibition
PL2254591T3 (pl) * 2008-02-08 2018-01-31 Prothera Inc Inhibicja i leczenie biofilmów żołądkowo-jelitowych
WO2011063394A2 (en) * 2009-11-23 2011-05-26 Olmstead Stephen F Compositions and methods comprising serratia peptidase for inhibition and treatment of biofilms related to certain conditions

Also Published As

Publication number Publication date
US20120315260A1 (en) 2012-12-13
EP2717926A2 (en) 2014-04-16
WO2012173796A3 (en) 2013-05-02
EP2717926A4 (en) 2014-12-31
EP2717926B1 (en) 2017-05-24
WO2012173796A2 (en) 2012-12-20
JP2015502179A (ja) 2015-01-22

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