DK270983A - 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepiner, en fremgangsmaade til fremstilling deraf og deres anvendelse - Google Patents

1-aryloxy-2,3,4,5-tetrahydro-3-benzazepiner, en fremgangsmaade til fremstilling deraf og deres anvendelse Download PDF

Info

Publication number
DK270983A
DK270983A DK270983A DK270983A DK270983A DK 270983 A DK270983 A DK 270983A DK 270983 A DK270983 A DK 270983A DK 270983 A DK270983 A DK 270983A DK 270983 A DK270983 A DK 270983A
Authority
DK
Denmark
Prior art keywords
sub
hydrogen
lower alkyl
benzazepines
tetrahydro
Prior art date
Application number
DK270983A
Other languages
Danish (da)
English (en)
Other versions
DK270983D0 (da
Inventor
Richard Charles Effland
Joseph Thomas Klein
Larry Davis
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of DK270983D0 publication Critical patent/DK270983D0/da
Publication of DK270983A publication Critical patent/DK270983A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK270983A 1982-06-14 1983-06-13 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepiner, en fremgangsmaade til fremstilling deraf og deres anvendelse DK270983A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/387,916 US4988690A (en) 1982-06-14 1982-06-14 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines and anti-depressant use thereof

Publications (2)

Publication Number Publication Date
DK270983D0 DK270983D0 (da) 1983-06-13
DK270983A true DK270983A (da) 1983-12-15

Family

ID=23531838

Family Applications (1)

Application Number Title Priority Date Filing Date
DK270983A DK270983A (da) 1982-06-14 1983-06-13 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepiner, en fremgangsmaade til fremstilling deraf og deres anvendelse

Country Status (17)

Country Link
US (1) US4988690A (hu)
EP (1) EP0096838B1 (hu)
JP (1) JPS595165A (hu)
KR (1) KR900001214B1 (hu)
AT (1) ATE26263T1 (hu)
AU (1) AU570920B2 (hu)
CA (1) CA1214460A (hu)
DE (1) DE3370621D1 (hu)
DK (1) DK270983A (hu)
ES (1) ES8503666A1 (hu)
FI (1) FI78473C (hu)
GR (1) GR78291B (hu)
HU (1) HU190902B (hu)
IE (1) IE55404B1 (hu)
IL (1) IL68964A (hu)
PT (1) PT76864B (hu)
ZA (1) ZA834309B (hu)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH27337A (en) * 1987-03-27 1993-06-08 Schering Corp Substituted benzazepines their preparation and pharmaceutical compositions containing them
US5015639A (en) * 1987-03-27 1991-05-14 Schering Corporation Substituted benzazepines, their preparation and pharmaceutical compositions containing them
ZA885824B (en) * 1987-08-14 1989-04-26 Merrell Dow Pharma Novel antidepressants
US5202319A (en) * 1991-09-23 1993-04-13 Hoechst-Roussel Pharmaceuticals Inc. Substituted 3-amino-2,3,4,5-tetrahydro-1-aryloxy-3-benzazepines
US5639482A (en) * 1993-11-10 1997-06-17 Crary; Ely J. Composition for control and prevention of diabetic retinopathy
US7115766B2 (en) * 2000-11-30 2006-10-03 Indiana University Research & Technology Corp. Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds
US6953787B2 (en) * 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
WO2005003096A1 (en) * 2003-06-17 2005-01-13 Arena Pharmaceuticals, Inc. Benzazepine derivatives useful for the treatment of 5ht2c receptor associated diseases
ES2571220T3 (es) 2003-06-17 2016-05-24 Arena Pharm Inc Clorhidrato de 8-cloro-1-metil-2,3,4,5-tetrahidro-1H-3-benzazepina
US20080009478A1 (en) * 2003-10-22 2008-01-10 Arena Pharmaceuticals, Inc. Benzazepine Derivatives and Methods of Prophylaxis or Treatment of 5Ht2c Receptor Associated Diseases
US20070275949A1 (en) * 2003-10-22 2007-11-29 Arena Pharmaceuticals, Inc. Benzazepine Derivatives and Methods of Prophylaxis or Treatment of 5Ht2C Receptor Associated Diseases
US8168624B2 (en) 2004-12-21 2012-05-01 Arena Pharmaceuticals, Inc. Crystalline forms of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
CN102627607A (zh) * 2004-12-23 2012-08-08 艾尼纳制药公司 5HT2c受体调节剂组合物和使用方法
CA2646044A1 (en) 2006-04-03 2007-10-25 Arena Pharmaceuticals, Inc. Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates related thereto
SG177128A1 (en) * 2006-12-05 2012-01-30 Arena Pharm Inc Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof
BRPI0811200A8 (pt) 2007-05-10 2015-09-22 Bristol Myers Squibb Co Tetra-hidrobenzapinas arilóxi- e heteroarilóxi-substituídas e uso das mesmas para bloquear percepção de norepinefrina, dopamina, e serotonina
US8822727B2 (en) 2008-03-04 2014-09-02 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-HT2C agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
US8952197B2 (en) 2009-06-18 2015-02-10 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-HT2C receptor agonists
WO2011153206A1 (en) 2010-06-02 2011-12-08 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-ht2c receptor agonists
CN103189053A (zh) 2010-09-01 2013-07-03 艾尼纳制药公司 用于体重控制的5-ht2c激动剂的调节释放剂型
MX2013002418A (es) 2010-09-01 2013-08-01 Arena Pharm Inc Administracion de lorcaserina a individuos con daño renal.
WO2012030957A2 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
MX2013002422A (es) 2010-09-01 2013-05-17 Arena Pharm Inc Sales de lorcaserina con acidos opticamente activos.
MY181736A (en) 2012-10-09 2021-01-05 Arena Pharm Inc Method of weight management

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5233687A (en) * 1975-09-11 1977-03-14 Shionogi & Co Ltd Process for preparation of 1,5-dihydro-2h-1,4-benzodiazepine-2-on deri vatives
JPS5481290A (en) * 1977-11-17 1979-06-28 Smithkline Corp Benzazepin compound

Also Published As

Publication number Publication date
US4988690A (en) 1991-01-29
AU1576483A (en) 1983-12-22
ES523191A0 (es) 1985-03-01
FI78473B (fi) 1989-04-28
IL68964A (en) 1988-03-31
GR78291B (hu) 1984-09-26
FI78473C (fi) 1989-08-10
HU190902B (en) 1986-12-28
EP0096838A1 (en) 1983-12-28
IE55404B1 (en) 1990-09-12
EP0096838B1 (en) 1987-04-01
KR900001214B1 (ko) 1990-02-28
ES8503666A1 (es) 1985-03-01
IE831384L (en) 1983-12-14
FI832092A0 (fi) 1983-06-10
PT76864A (en) 1983-07-01
IL68964A0 (en) 1983-10-31
JPS595165A (ja) 1984-01-12
DK270983D0 (da) 1983-06-13
AU570920B2 (en) 1988-03-31
PT76864B (en) 1986-02-27
ATE26263T1 (de) 1987-04-15
CA1214460A (en) 1986-11-25
ZA834309B (en) 1984-03-28
JPH0365342B2 (hu) 1991-10-11
DE3370621D1 (en) 1987-05-07
FI832092L (fi) 1983-12-15
KR840005103A (ko) 1984-11-03

Similar Documents

Publication Publication Date Title
DK270983A (da) 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepiner, en fremgangsmaade til fremstilling deraf og deres anvendelse
MY109937A (en) Substituted azoles, processes for the preparation thereof, agents containing these, and the use thereof.
EP0202577A3 (en) N(acyldipeptidyl)-aminoglycols
EP0254327A3 (en) N-n-disubstituted-omega-(2-amino-3-(carbonylmethyl)-3,4-dihydroquinazolinyl) oxyalkylamides and related compounds
ES8401961A1 (es) Procedimiento para la preparacion de nuevas n-(4-indolil-piperidino-alcohil-bencimidazolonas sustituidas.
ES8609204A1 (es) Procedimiento de preparar derivados aminicos
DK286982A (da) Fremgangsmaade til fremstilling af pyrimidonderivater
ES8601201A1 (es) Procedimiento para preparar derivados de imidazolina
DK322588A (da) Cycloalkylamider af 6-substituerede (8beta)-1-alkylergoliner og fremgangsmaade til fremstilling af saadanne forbindelser
ES8308543A1 (es) "procedimiento para la preparacion de nuevas 2-fenil-2-(piridiloxi)-etilaminas sustituidas".
EP0251574A3 (en) Antifungal derivatives of n-(6,6-dimethyl-2-hepten-4-ynyl)-1-naphthalenemethanamine and method of using same
DK440987D0 (da) Thyroninderivater, deres fremstilling og anvendelse
HUT43568A (en) Process for preparing novel 2-pyridiyl-acetic acid derivatives and pharmaceutics comprising the same
GR880100112A (en) Method of preparation of new acetamide deravatives of dihydro-2,3 phenyl-3 benzophouranone-2
GR81771B (hu)
ES8703457A1 (es) Un procedimiento para la preparacion de nuevos derivados de tiacetona.
DE3662039D1 (de) Novel diamine derivatives
DK60793D0 (da) Kemiske forbindelser, deres fremstilling og anvendelse
ES8600206A1 (es) Procedimiento de preparacion de derivados alquilenodiaminos

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment