DK2646443T3 - CAT-II inhibitors - Google Patents
CAT-II inhibitors Download PDFInfo
- Publication number
- DK2646443T3 DK2646443T3 DK11804801.6T DK11804801T DK2646443T3 DK 2646443 T3 DK2646443 T3 DK 2646443T3 DK 11804801 T DK11804801 T DK 11804801T DK 2646443 T3 DK2646443 T3 DK 2646443T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- aryl
- mmol
- pharmaceutically acceptable
- substituted
- Prior art date
Links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Health & Medical Sciences (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41880210P | 2010-12-01 | 2010-12-01 | |
| PCT/IB2011/055158 WO2012073143A1 (en) | 2010-12-01 | 2011-11-17 | Kat ii inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2646443T3 true DK2646443T3 (en) | 2014-11-17 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11804801.6T DK2646443T3 (en) | 2010-12-01 | 2011-11-17 | CAT-II inhibitors |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8598200B2 (https=) |
| EP (1) | EP2646443B1 (https=) |
| JP (1) | JP2013544277A (https=) |
| KR (1) | KR101544290B1 (https=) |
| CN (1) | CN103228660A (https=) |
| AU (1) | AU2011336214B2 (https=) |
| CA (1) | CA2819102A1 (https=) |
| DK (1) | DK2646443T3 (https=) |
| ES (1) | ES2524423T3 (https=) |
| MX (1) | MX2013005773A (https=) |
| SG (1) | SG190207A1 (https=) |
| WO (1) | WO2012073143A1 (https=) |
| ZA (1) | ZA201303360B (https=) |
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| EP2646417A1 (en) | 2010-12-01 | 2013-10-09 | Pfizer Inc | Kat ii inhibitors |
| US20140206667A1 (en) | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| BR112016024455B1 (pt) | 2014-04-23 | 2023-02-07 | Mitsubishi Tanabe Pharma Corporation | Composto heterocíclico bicíclico ou tricíclico |
| WO2016164754A1 (en) | 2015-04-09 | 2016-10-13 | Eisai R&D Management Co., Ltd. | Fgfr4 inhibitors |
| WO2016164703A1 (en) | 2015-04-09 | 2016-10-13 | Eisai R & D Management Co., Ltd. | Fgfr4 inhibitors |
| CA2998753A1 (en) | 2015-09-18 | 2017-03-23 | St. Jude Children's Research Hospital | Methods and compositions of inhibiting dcn1-ubc12 interaction |
| US10793582B2 (en) | 2015-10-22 | 2020-10-06 | Mitsubishi Tanabe Pharma Corporation | Bicyclic heterocyclic compound |
| WO2020257790A1 (en) * | 2019-06-20 | 2020-12-24 | University Of Kentucky Research Foundation | Pharmaceutically active pyrazolo-pyridone modulators of dcn1/2-mediated cullin neddylation |
| CN115038443A (zh) | 2019-11-22 | 2022-09-09 | 因西特公司 | 包含alk2抑制剂和jak2抑制剂的组合疗法 |
| KR102698413B1 (ko) | 2020-05-05 | 2024-08-26 | 뉴베일런트, 아이엔씨. | 헤테로방향족 거대환식 에터 화학치료제 |
| IL297832A (en) | 2020-05-05 | 2023-01-01 | Nuvalent Inc | Macrocyclic heteroaromatic chemotherapeutic agents |
| WO2022165382A1 (en) * | 2021-01-29 | 2022-08-04 | Neurawell Therapeutics | Phenylethylidenehydrazine combination therapies |
| IL311444A (en) | 2021-10-01 | 2024-05-01 | Nuvalent Inc | Solid forms, pharmaceutical compositions and preparation of heteroaromatic macrocyclic ether compounds |
| WO2025096981A1 (en) * | 2023-11-03 | 2025-05-08 | Cellarity, Inc. | Modulators of dcn-1 and methods of use thereof |
| US12473285B2 (en) | 2023-11-03 | 2025-11-18 | Cellarity, Inc. | DCN-1 modulating compounds and methods of use thereof |
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| US4282361A (en) | 1978-03-16 | 1981-08-04 | Massachusetts Institute Of Technology | Synthesis for 7-alkylamino-3-methylpyrazolo [4,3-d]pyrimidines |
| US5519055A (en) * | 1993-08-06 | 1996-05-21 | University Of Maryland At Baltimore | Substituted kynurenines and process for their preparation |
| US7276608B2 (en) * | 2003-07-11 | 2007-10-02 | Bristol-Myers Squibb Company | Tetrahydroquinoline derivatives as cannabinoid receptor modulators |
| GT200500186A (es) | 2004-07-07 | 2006-03-02 | Regimenes anticonceptivos con antagonistas del receptor de progesterona y kits | |
| JP2008517994A (ja) | 2004-10-28 | 2008-05-29 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 新規医薬品 |
| CA2626897A1 (en) | 2005-11-03 | 2007-05-18 | Joshua Close | Histone deacetylase inhibitors with aryl-pyrazolyl motifs |
| CA2635209A1 (en) | 2006-01-12 | 2007-08-02 | Merck & Co., Inc. | Fluorinated arylamide derivatives |
| EP2049548A1 (en) | 2006-07-27 | 2009-04-22 | UCB Pharma, S.A. | Fused oxazoles & thiazoles as histamine h3- receptor ligands |
| WO2009064836A2 (en) * | 2007-11-15 | 2009-05-22 | University Of Maryland, Baltimore | Kynurenine-aminotransferase inhibitors |
| WO2009095752A1 (en) * | 2008-01-29 | 2009-08-06 | Glenmark Pharmaceuticals, S.A. | Fused pyrazole derivatives as cannabinoid receptor modulators |
| US9293849B2 (en) | 2008-07-30 | 2016-03-22 | Bal Seal Engineering, Inc. | Electrical connector using a canted coil multi-metallic wire |
| WO2010146488A1 (en) * | 2009-06-18 | 2010-12-23 | Pfizer Inc. | Bicyclic and tricyclic compounds as kat ii inhibitors |
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2011
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- 2011-11-17 CN CN2011800578092A patent/CN103228660A/zh active Pending
- 2011-11-17 CA CA2819102A patent/CA2819102A1/en not_active Abandoned
- 2011-11-17 EP EP11804801.6A patent/EP2646443B1/en not_active Not-in-force
- 2011-11-17 WO PCT/IB2011/055158 patent/WO2012073143A1/en not_active Ceased
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- 2011-11-17 SG SG2013035399A patent/SG190207A1/en unknown
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- 2011-11-17 AU AU2011336214A patent/AU2011336214B2/en not_active Expired - Fee Related
- 2011-11-17 JP JP2013541446A patent/JP2013544277A/ja not_active Ceased
- 2011-11-17 KR KR1020137014065A patent/KR101544290B1/ko not_active Expired - Fee Related
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2013
- 2013-05-09 ZA ZA2013/03360A patent/ZA201303360B/en unknown
- 2013-10-31 US US14/068,707 patent/US8933095B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| SG190207A1 (en) | 2013-06-28 |
| KR101544290B1 (ko) | 2015-08-12 |
| US20120302599A1 (en) | 2012-11-29 |
| US8598200B2 (en) | 2013-12-03 |
| ES2524423T3 (es) | 2014-12-09 |
| JP2013544277A (ja) | 2013-12-12 |
| US8933095B2 (en) | 2015-01-13 |
| MX2013005773A (es) | 2013-06-18 |
| US20140057938A1 (en) | 2014-02-27 |
| WO2012073143A1 (en) | 2012-06-07 |
| KR20130108618A (ko) | 2013-10-04 |
| CA2819102A1 (en) | 2012-06-07 |
| EP2646443A1 (en) | 2013-10-09 |
| ZA201303360B (en) | 2014-07-30 |
| AU2011336214B2 (en) | 2015-08-20 |
| EP2646443B1 (en) | 2014-09-24 |
| CN103228660A (zh) | 2013-07-31 |
| AU2011336214A1 (en) | 2013-05-30 |
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