DK2641601T3 - Methods for treating multiple myeloma using the combination therapy based on HuLuc63 with bortezomib - Google Patents
Methods for treating multiple myeloma using the combination therapy based on HuLuc63 with bortezomib Download PDFInfo
- Publication number
- DK2641601T3 DK2641601T3 DK13168383.1T DK13168383T DK2641601T3 DK 2641601 T3 DK2641601 T3 DK 2641601T3 DK 13168383 T DK13168383 T DK 13168383T DK 2641601 T3 DK2641601 T3 DK 2641601T3
- Authority
- DK
- Denmark
- Prior art keywords
- huluc63
- bortezomib
- administered
- ser
- leu
- Prior art date
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- C07—ORGANIC CHEMISTRY
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| EP07840746.7A EP2068874B1 (en) | 2006-08-07 | 2007-08-07 | Methods of treating multiple myeloma using combination therapies based on anti-cs1 antibodies |
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| JP2010500370A (ja) | 2006-08-07 | 2010-01-07 | ピーディーエル バイオファーマ，インコーポレイティド | 多発性硬化症を処置するための抗ｃｓ１抗体を用いる組成物および方法 |
| HUE029027T2 (en) | 2006-08-07 | 2017-01-30 | Abbvie Biotherapeutics Inc | Procedures for Multiple Myeloma Treatment Using HuLuc63 and Bortezomib Combination Therapies |
| JP2011523560A (ja) | 2008-06-02 | 2011-08-18 | ダナ−ファーバー キャンサー インスティテュート インク． | Ｘｂｐ１ペプチド、ｃｄ１３８ペプチドおよびｃｓ１ペプチド |
| NZ589880A (en) | 2008-06-16 | 2012-10-26 | Immunogen Inc | Use of synergistic anti-cancer compositions comprising lenalidomide, at least one corticosteroid and at least one immunoconjugate |
| PE20120059A1 (es) * | 2008-10-21 | 2012-02-27 | Onyx Therapeutics Inc | Combinaciones farmaceuticas con epoxicetonas peptidicas |
| EP2476438B1 (en) * | 2009-09-10 | 2014-07-23 | Kyowa Hakko Kirin Co., Ltd. | Medicament including antibody composition specifically bound to human cc chemokine receptor 4 (ccr4) |
| CA2780998C (en) * | 2009-11-24 | 2016-07-12 | Celgene Corporation | Immunomodulatory compounds for the restoration of vitamin d sensitivity in vitamin d resistant tumor cells |
| CN102241773B (zh) * | 2010-05-13 | 2014-05-14 | 四川大学 | 抗骨髓瘤细胞多克隆抗体及其制备方法 |
| CN105377288B (zh) | 2012-11-05 | 2019-11-15 | 达纳-法伯癌症研究所股份有限公司 | Xbp1、cd138和cs1肽的组合物制备药物的用途 |
| EP3066127A1 (en) | 2013-11-06 | 2016-09-14 | Bristol-Myers Squibb Company | Immunotherapeutic dosing regimens and combinations thereof |
| WO2015069785A1 (en) * | 2013-11-06 | 2015-05-14 | Bristol-Myers Squibb Company | Combination of anti-kir and anti-cs1 antibodies to treat multiple myeloma |
| CA2924268C (en) * | 2013-11-21 | 2021-05-18 | F. Hoffmann-La Roche Ag | Anti-alpha-synuclein antibodies and methods of use |
| LT3182996T (lt) * | 2014-08-22 | 2023-03-10 | Celgene Corporation | Daugybinės mielomos gydymo būdai imunomoduliuojančiais junginiais derinyje su antikūnais |
| WO2016049022A1 (en) * | 2014-09-23 | 2016-03-31 | Board Of Trustees Of Michigan State University | Compositions and methods for modulating an immune response |
| WO2016054354A1 (en) | 2014-10-02 | 2016-04-07 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for treating malignancies |
| WO2016070089A2 (en) | 2014-10-31 | 2016-05-06 | Abbvie Biotherapeutics Inc. | Anti-cs1 antibodies and antibody drug conjugates |
| US10302644B2 (en) | 2014-11-04 | 2019-05-28 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for treating multiple myeloma |
| BR112017011538A2 (pt) * | 2014-12-04 | 2018-03-13 | Bristol-Myers Squibb Company | combinação de anticorpos anti-cs1 e anti-pd1 para tratar câncer (mieloma) |
| HRP20210552T1 (hr) | 2015-05-13 | 2021-05-14 | Morphosys Ag | Liječenje multiplog mijeloma (mm) |
| ES2886657T3 (es) * | 2015-06-29 | 2021-12-20 | Bristol Myers Squibb Co | Regímenes de dosificación inmunoterapéutica que comprenden pomalidomida y un anticuerpo anti-CS1 para el tratamiento de cáncer |
| CN109432398A (zh) * | 2016-03-13 | 2019-03-08 | 曹帅 | 一种用于治疗骨髓增生、骨癌的药物组合物及其用途 |
| SG11201907923VA (en) | 2017-03-29 | 2019-09-27 | Agency Science Tech & Res | Anti oligosaccharide antibody |
| JP2021504475A (ja) * | 2017-11-22 | 2021-02-15 | ヒルストリーム・バイオファーマ・インコーポレイテッド | ボルテゾミブを含むポリマーナノ粒子 |
| US10537585B2 (en) | 2017-12-18 | 2020-01-21 | Dexcel Pharma Technologies Ltd. | Compositions comprising dexamethasone |
| KR20220092578A (ko) | 2019-11-05 | 2022-07-01 | 브리스톨-마이어스 스큅 컴퍼니 | M-단백질 검정 및 이의 용도 |
| CN115368462A (zh) * | 2022-07-19 | 2022-11-22 | 合肥天港免疫药物有限公司 | 双特异性抗体及其应用 |
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| IL112969A (en) | 1994-03-17 | 2001-05-20 | Baxter Int | Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator |
| WO1996037208A1 (en) | 1995-05-25 | 1996-11-28 | Baxter International Inc. | Allogeneic cell therapy for cancer following allogeneic stem cell transplantation |
| US7968569B2 (en) * | 2002-05-17 | 2011-06-28 | Celgene Corporation | Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione |
| CA2752140A1 (en) * | 2002-05-17 | 2003-11-27 | Celgene Corporation | Methods and compositions using 3-(4-amino-1-oxo-1,3-dihydroisoindol-1-yl)-piperidine-2,6-dione for treatment and management of renal cancer |
| US7709610B2 (en) | 2003-05-08 | 2010-05-04 | Facet Biotech Corporation | Therapeutic use of anti-CS1 antibodies |
| US20050025763A1 (en) | 2003-05-08 | 2005-02-03 | Protein Design Laboratories, Inc. | Therapeutic use of anti-CS1 antibodies |
| EP1824513A4 (en) * | 2004-11-04 | 2010-06-09 | Fibron Ltd | TREATMENT OF B-CELL TUMORS |
| JP2010500370A (ja) | 2006-08-07 | 2010-01-07 | ピーディーエル バイオファーマ，インコーポレイティド | 多発性硬化症を処置するための抗ｃｓ１抗体を用いる組成物および方法 |
| HUE029027T2 (en) | 2006-08-07 | 2017-01-30 | Abbvie Biotherapeutics Inc | Procedures for Multiple Myeloma Treatment Using HuLuc63 and Bortezomib Combination Therapies |
| US20080095768A1 (en) | 2006-08-07 | 2008-04-24 | Pdl Biopharma, Inc. | Use of allogeneic effector cells and anti-cs1 antibodies for selective killing of multiple myeloma cells |
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2017
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