DK2555789T3 - Hæmmende peptider afledt af trem-lignende transcript 1 (tlt-1) og anvendelser deraf - Google Patents

Hæmmende peptider afledt af trem-lignende transcript 1 (tlt-1) og anvendelser deraf Download PDF

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Publication number
DK2555789T3
DK2555789T3 DK11718957.1T DK11718957T DK2555789T3 DK 2555789 T3 DK2555789 T3 DK 2555789T3 DK 11718957 T DK11718957 T DK 11718957T DK 2555789 T3 DK2555789 T3 DK 2555789T3
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DK
Denmark
Prior art keywords
inhibitant
trem
tlt
transcript
peptides derived
Prior art date
Application number
DK11718957.1T
Other languages
English (en)
Inventor
Sébastien Gibot
Marc Derive
Original Assignee
Inst Nat Sante Rech Med
Univ De Lorraine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Inst Nat Sante Rech Med, Univ De Lorraine filed Critical Inst Nat Sante Rech Med
Application granted granted Critical
Publication of DK2555789T3 publication Critical patent/DK2555789T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK11718957.1T 2010-04-08 2011-04-08 Hæmmende peptider afledt af trem-lignende transcript 1 (tlt-1) og anvendelser deraf DK2555789T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10305364 2010-04-08
PCT/EP2011/055519 WO2011124685A1 (en) 2010-04-08 2011-04-08 Inhibiting peptides derived from trem-like transcript 1 (tlt-1) and uses thereof

Publications (1)

Publication Number Publication Date
DK2555789T3 true DK2555789T3 (da) 2020-07-20

Family

ID=42262363

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11718957.1T DK2555789T3 (da) 2010-04-08 2011-04-08 Hæmmende peptider afledt af trem-lignende transcript 1 (tlt-1) og anvendelser deraf

Country Status (18)

Country Link
US (2) US9255136B2 (da)
EP (2) EP3741383A1 (da)
JP (2) JP5918750B2 (da)
CN (1) CN103153327B (da)
AU (1) AU2011237851B2 (da)
CA (1) CA2795390C (da)
CY (1) CY1123304T1 (da)
DK (1) DK2555789T3 (da)
ES (1) ES2805301T3 (da)
HR (1) HRP20201081T1 (da)
HU (1) HUE050815T2 (da)
LT (1) LT2555789T (da)
NZ (1) NZ602845A (da)
PL (1) PL2555789T3 (da)
PT (1) PT2555789T (da)
RS (1) RS60636B1 (da)
SI (1) SI2555789T1 (da)
WO (1) WO2011124685A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2015002994A (es) 2012-09-07 2016-01-14 Inserm Inst Nat De La Santé Et De La Rech Médicale Peptidos de inhibidores obtenidos del receptor desencadenante expresado en celulas mieloides de tipo 1 (trem-1) y transcrito similar a trem 1 (tlt-1) y usos de los mismos.
KR101404098B1 (ko) * 2012-11-29 2014-06-05 성균관대학교산학협력단 금속 나노와이어-유기화합물 복합체, 이를 포함하는 필름, 및 이의 제조 방법
CN108135961A (zh) * 2015-06-12 2018-06-08 台湾基督长老教会马偕医疗财团法人马偕纪念医院 调控免疫反应的方法及多肽
JOP20190248A1 (ar) 2017-04-21 2019-10-20 Amgen Inc بروتينات ربط مولد ضد trem2 واستخداماته
CN108276488B (zh) * 2018-01-26 2020-06-19 四川农业大学 一种鸡髓样细胞触发受体b2多克隆抗体及其制备方法和应用
EP3836951A1 (en) 2018-08-13 2021-06-23 Signablok, Inc. Peptides and compositions for targeted treatment and imaging
CA3114503A1 (en) * 2018-09-28 2020-04-02 Inotrem Use of soluble trem-1 levels for identifying subjects susceptible to respond to an anti-inflammatory therapy
EP3956359A1 (en) 2019-04-17 2022-02-23 Novo Nordisk A/S Bispecific antibodies
CN114945580B (zh) * 2020-01-15 2023-12-15 北京费森尤斯卡比医药有限公司 用于合成南吉博肽的方法
US20230330222A1 (en) * 2020-05-14 2023-10-19 Ascendo Biotechnology, Inc. Selective targeting of the treml1/md2 interaction by small peptide or protein and its use for vaccine adjuvants
CN116490199A (zh) * 2020-06-05 2023-07-25 伊诺特伦公司 用于治疗患有冠状病毒感染的受试者的trem-1抑制剂
JP2024521904A (ja) 2021-06-02 2024-06-04 イノトレム 抗trem-1抗体
CN113755580B (zh) * 2021-09-13 2023-10-27 中国医学科学院阜外医院 一种治疗和/或缓解淋巴水肿的药物干预靶点及其应用
CN118359676A (zh) * 2023-01-19 2024-07-19 武汉人福创新药物研发中心有限公司 作为Trem-1抑制剂的修饰肽

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US2005261A (en) 1933-05-24 1935-06-18 Leland Electric Co Riveting machine
US4861719A (en) 1986-04-25 1989-08-29 Fred Hutchinson Cancer Research Center DNA constructs for retrovirus packaging cell lines
US5278056A (en) 1988-02-05 1994-01-11 The Trustees Of Columbia University In The City Of New York Retroviral packaging cell lines and process of using same
US5670488A (en) 1992-12-03 1997-09-23 Genzyme Corporation Adenovirus vector for gene therapy
EP1493825A3 (en) 1990-06-11 2005-02-09 Gilead Sciences, Inc. Method for producing nucleic acid ligands
US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
DE69434860T2 (de) 1993-02-22 2007-03-15 The Rockefeller University Herstellung von helfer-freien retroviren mit hohem titer mittels transienter transfektion
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IL116816A (en) 1995-01-20 2003-05-29 Rhone Poulenc Rorer Sa Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof
US6013516A (en) 1995-10-06 2000-01-11 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
US7129072B1 (en) 1999-08-30 2006-10-31 New York University Crystal of fibroblast growth factor receptor 1 in complex with fibroblast growth factor
WO2001043695A2 (en) 1999-10-27 2001-06-21 Cel-Sci Corporation Peptide constructs for treating autoimmune and related diseases
JP2001210726A (ja) * 2000-01-24 2001-08-03 Hitachi Ltd 半導体装置及びその製造方法
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Also Published As

Publication number Publication date
EP2555789A1 (en) 2013-02-13
AU2011237851A1 (en) 2012-11-01
HUE050815T2 (hu) 2021-01-28
HRP20201081T1 (hr) 2021-01-22
JP2013523140A (ja) 2013-06-17
CN103153327A (zh) 2013-06-12
CA2795390C (en) 2020-11-03
AU2011237851B2 (en) 2015-02-05
CN103153327B (zh) 2016-01-20
US9255136B2 (en) 2016-02-09
ES2805301T3 (es) 2021-02-11
JP5918750B2 (ja) 2016-05-18
RS60636B1 (sr) 2020-09-30
CY1123304T1 (el) 2021-12-31
JP2016169208A (ja) 2016-09-23
SI2555789T1 (sl) 2020-10-30
WO2011124685A1 (en) 2011-10-13
US9815883B2 (en) 2017-11-14
PL2555789T3 (pl) 2021-02-08
EP2555789B1 (en) 2020-06-10
PT2555789T (pt) 2020-07-14
US20130029921A1 (en) 2013-01-31
NZ602845A (en) 2015-05-29
US20160015773A1 (en) 2016-01-21
EP3741383A1 (en) 2020-11-25
CA2795390A1 (en) 2011-10-13
LT2555789T (lt) 2020-09-25

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