LT2555789T - Inhibuojantys peptidai, kilę iš trem tipo transkripto 1 (tlt-1), ir jų naudojimas - Google Patents

Inhibuojantys peptidai, kilę iš trem tipo transkripto 1 (tlt-1), ir jų naudojimas

Info

Publication number
LT2555789T
LT2555789T LTEP11718957.1T LT11718957T LT2555789T LT 2555789 T LT2555789 T LT 2555789T LT 11718957 T LT11718957 T LT 11718957T LT 2555789 T LT2555789 T LT 2555789T
Authority
LT
Lithuania
Prior art keywords
trem
tlt
transcript
peptides derived
inhibiting peptides
Prior art date
Application number
LTEP11718957.1T
Other languages
English (en)
Inventor
Sébastien GIBOT
Marc Derive
Original Assignee
INSERM (Institut National de la Santé et de la Recherche Médicale)
Université De Lorraine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INSERM (Institut National de la Santé et de la Recherche Médicale), Université De Lorraine filed Critical INSERM (Institut National de la Santé et de la Recherche Médicale)
Publication of LT2555789T publication Critical patent/LT2555789T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LTEP11718957.1T 2010-04-08 2011-04-08 Inhibuojantys peptidai, kilę iš trem tipo transkripto 1 (tlt-1), ir jų naudojimas LT2555789T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10305364 2010-04-08
PCT/EP2011/055519 WO2011124685A1 (en) 2010-04-08 2011-04-08 Inhibiting peptides derived from trem-like transcript 1 (tlt-1) and uses thereof

Publications (1)

Publication Number Publication Date
LT2555789T true LT2555789T (lt) 2020-09-25

Family

ID=42262363

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP11718957.1T LT2555789T (lt) 2010-04-08 2011-04-08 Inhibuojantys peptidai, kilę iš trem tipo transkripto 1 (tlt-1), ir jų naudojimas

Country Status (18)

Country Link
US (2) US9255136B2 (lt)
EP (2) EP2555789B1 (lt)
JP (2) JP5918750B2 (lt)
CN (1) CN103153327B (lt)
AU (1) AU2011237851B2 (lt)
CA (1) CA2795390C (lt)
CY (1) CY1123304T1 (lt)
DK (1) DK2555789T3 (lt)
ES (1) ES2805301T3 (lt)
HR (1) HRP20201081T1 (lt)
HU (1) HUE050815T2 (lt)
LT (1) LT2555789T (lt)
NZ (1) NZ602845A (lt)
PL (1) PL2555789T3 (lt)
PT (1) PT2555789T (lt)
RS (1) RS60636B1 (lt)
SI (1) SI2555789T1 (lt)
WO (1) WO2011124685A1 (lt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102181384B1 (ko) * 2012-09-07 2020-11-20 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) 골수세포-1 상에 발현되는 촉발 수용체(trem-1) trem-유사 전사체 1(tlt-1)로부터 유도되는 억제 펩타이드 및 그의 용도
KR101404098B1 (ko) * 2012-11-29 2014-06-05 성균관대학교산학협력단 금속 나노와이어-유기화합물 복합체, 이를 포함하는 필름, 및 이의 제조 방법
AU2016274175B2 (en) * 2015-06-12 2021-02-18 Mackay Medical Foundation The Presbyterian Church In Taiwan Mackay Memorial Hospital Methods and polypeptides for modulation of immunoresponse
JOP20190248A1 (ar) 2017-04-21 2019-10-20 Amgen Inc بروتينات ربط مولد ضد trem2 واستخداماته
CN108276488B (zh) * 2018-01-26 2020-06-19 四川农业大学 一种鸡髓样细胞触发受体b2多克隆抗体及其制备方法和应用
WO2020036987A1 (en) 2018-08-13 2020-02-20 Signablok, Inc. Peptides and compositions for targeted treatment and imaging
CN113164546A (zh) * 2018-09-28 2021-07-23 伊诺特伦公司 可溶的trem-1水平用于鉴定对抗炎疗法应答敏感的受试者的用途
KR20240046282A (ko) 2019-04-17 2024-04-08 노보 노르디스크 에이/에스 이중 특이적 항체
CN114945580B (zh) * 2020-01-15 2023-12-15 北京费森尤斯卡比医药有限公司 用于合成南吉博肽的方法
JP2023527716A (ja) * 2020-05-14 2023-06-30 アセンド バイオテクノロジー インク 小ペプチド又はタンパク質によるtreml1/md2相互作用の選択的ターゲティング及びワクチンアジュバントのためのその使用
EP4161551A1 (en) * 2020-06-05 2023-04-12 Inotrem Trem-1 inhibitor for use in the treatment of a subject suffering from a coronavirus infection
JP2024521904A (ja) 2021-06-02 2024-06-04 イノトレム 抗trem-1抗体
CN113755580B (zh) * 2021-09-13 2023-10-27 中国医学科学院阜外医院 一种治疗和/或缓解淋巴水肿的药物干预靶点及其应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2005261A (en) 1933-05-24 1935-06-18 Leland Electric Co Riveting machine
US4861719A (en) 1986-04-25 1989-08-29 Fred Hutchinson Cancer Research Center DNA constructs for retrovirus packaging cell lines
US5278056A (en) 1988-02-05 1994-01-11 The Trustees Of Columbia University In The City Of New York Retroviral packaging cell lines and process of using same
US5670488A (en) 1992-12-03 1997-09-23 Genzyme Corporation Adenovirus vector for gene therapy
US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
EP1493825A3 (en) 1990-06-11 2005-02-09 Gilead Sciences, Inc. Method for producing nucleic acid ligands
DE69434860T2 (de) 1993-02-22 2007-03-15 The Rockefeller University Herstellung von helfer-freien retroviren mit hohem titer mittels transienter transfektion
FR2712812B1 (fr) 1993-11-23 1996-02-09 Centre Nat Rech Scient Composition pour la production de produits thérapeutiques in vivo.
IL116816A (en) 1995-01-20 2003-05-29 Rhone Poulenc Rorer Sa Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof
US6013516A (en) 1995-10-06 2000-01-11 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
US7129072B1 (en) 1999-08-30 2006-10-31 New York University Crystal of fibroblast growth factor receptor 1 in complex with fibroblast growth factor
AU4705201A (en) * 1999-10-27 2001-06-25 Cel-Sci Corporation Peptide constructs for treating autoimmune and related diseases
JP2001210726A (ja) * 2000-01-24 2001-08-03 Hitachi Ltd 半導体装置及びその製造方法
US20020031508A1 (en) * 2000-05-19 2002-03-14 Wagner Denisa D. Methods for diagnosing and treating hemostatic disorders by modulating P-selectin activity
ATE516304T1 (de) 2000-05-23 2011-07-15 Cenes Pharmaceuticals Inc Nrg-2 nukleinsäuren, polypeptide und diagnostische / therapeutische methoden
WO2003020005A2 (en) * 2001-09-05 2003-03-13 Eli Lilly And Company Lp mammalian proteins; related reagents
US20040180409A1 (en) * 2003-03-16 2004-09-16 Mcvicar Daniel TLT-1, a novel platelet-associated receptor and uses therefor
GB0426146D0 (en) 2004-11-29 2004-12-29 Bioxell Spa Therapeutic peptides and method
US20130332133A1 (en) 2006-05-11 2013-12-12 Ramot At Tel Aviv University Ltd. Classification of Protein Sequences and Uses of Classified Proteins
US7553936B2 (en) * 2006-12-04 2009-06-30 The United States of America as represented by Secretary Department of Health and Human Services Anti-TREM-like transcript-1 (TLT-1) antibodies and compositions
WO2010132370A2 (en) 2009-05-11 2010-11-18 Government Of The U.S.A., As Represented By The Secretary, Department Of Health And Human Services Soluble tlt-1 for the treatment and diagnosis of sepsis

Also Published As

Publication number Publication date
PL2555789T3 (pl) 2021-02-08
DK2555789T3 (da) 2020-07-20
RS60636B1 (sr) 2020-09-30
NZ602845A (en) 2015-05-29
JP2016169208A (ja) 2016-09-23
HRP20201081T1 (hr) 2021-01-22
CA2795390A1 (en) 2011-10-13
WO2011124685A1 (en) 2011-10-13
US20130029921A1 (en) 2013-01-31
JP5918750B2 (ja) 2016-05-18
AU2011237851B2 (en) 2015-02-05
EP3741383A1 (en) 2020-11-25
US20160015773A1 (en) 2016-01-21
EP2555789A1 (en) 2013-02-13
CN103153327A (zh) 2013-06-12
CY1123304T1 (el) 2021-12-31
CA2795390C (en) 2020-11-03
AU2011237851A1 (en) 2012-11-01
JP2013523140A (ja) 2013-06-17
CN103153327B (zh) 2016-01-20
ES2805301T3 (es) 2021-02-11
US9815883B2 (en) 2017-11-14
HUE050815T2 (hu) 2021-01-28
PT2555789T (pt) 2020-07-14
US9255136B2 (en) 2016-02-09
EP2555789B1 (en) 2020-06-10
SI2555789T1 (sl) 2020-10-30

Similar Documents

Publication Publication Date Title
HUE050815T2 (hu) A trem-szerû 1. transzkriptumból (tlt-1) származó gátló peptidek és azok felhasználása
HK1208686A1 (en) Aromatic-cationic peptides and uses of same
IL248880A0 (en) Preparations containing r-g-cysteic acid peptides and their uses
EP2566880A4 (en) AROMATIC-CATIONIC PEPTIDES AND USES THEREOF
PL2588491T3 (pl) Nowy peptyd i jego zastosowanie
EP2383283A4 (en) NOGGIN PEPTIDE AND ITS USE
EP2313498A4 (en) DETECTION SEQUENCES FOR MEGANUCLEASES FROM I-CREI AND ITS USE
EP2593595A4 (en) NOVEL PEPTIDES AND USES THEREOF
EP2474555A4 (en) PEPTIDE DERIVED FROM WNT10 AND USE THEREOF
EP2521564A4 (en) APOE PEPTIDE DIMERS AND USES THEREOF
EP2513137A4 (en) PEPTIDES DERIVED FROM SAPOSINE-A AND USES THEREOF
EP2793921A4 (en) PEPTIDES DERIVED FROM SAPOSIN A AND USES THEREOF
EP2471553A4 (en) IMMUNOGENIC COMPOSITION WITH PEPTIDES FROM CYTOMEGALOVIRUS AND THEIR USE
PL2627668T3 (pl) Peptydy i ich zastosowanie
PL3346273T3 (pl) Nowe, pochodzące od d3 d-enancjomeryczne peptydy i ich zastosowanie
HK1168363A1 (en) Novel peptide and use thereof
IL225464B (en) 2nd peptides, preparations containing them and their uses
EP2285827A4 (en) PEPTIDES AND ITS USE
SG173752A1 (en) Modifications of cupredoxin derived peptides and methods of use thereof
EP2358740A4 (en) CYCLIC PEPTIDES AND USES THEREOF
IL216199A (en) A peptide containing the sequence ednimvtfrnqasr
IL225405A0 (en) Methods for immune modulation and systems for the treatment and/or prevention of atherosclerosis, proteins, peptides and preparations.
EP2660249A4 (en) PEPTIDE DERIVATIVE AND USE THEREOF
GB2489887B (en) Cover for a laparoscope, systems including the cover and methods of use
EP2536431A4 (en) COMPOSITIONS AND METHODS FOR INHIBITING MMSET