DK2504331T3 - A compound, specific new forms, to pharmaceutical compositions thereof, and methods of making and using - Google Patents
A compound, specific new forms, to pharmaceutical compositions thereof, and methods of making and using Download PDFInfo
- Publication number
- DK2504331T3 DK2504331T3 DK10831161.4T DK10831161T DK2504331T3 DK 2504331 T3 DK2504331 T3 DK 2504331T3 DK 10831161 T DK10831161 T DK 10831161T DK 2504331 T3 DK2504331 T3 DK 2504331T3
- Authority
- DK
- Denmark
- Prior art keywords
- compound
- solution
- ethyl
- indol
- methyl
- Prior art date
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101992592A CN102070618B (zh) | 2009-11-23 | 2009-11-23 | 一种化合物及其晶体 |
| PCT/CN2010/078997 WO2011060746A1 (en) | 2009-11-23 | 2010-11-23 | Compound, certain novel forms thereof, pharmaceutical compositions thereof and methods for preparation and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2504331T3 true DK2504331T3 (en) | 2014-12-08 |
Family
ID=44029398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10831161.4T DK2504331T3 (en) | 2009-11-23 | 2010-11-23 | A compound, specific new forms, to pharmaceutical compositions thereof, and methods of making and using |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US8658658B2 (ref) |
| EP (1) | EP2504331B1 (ref) |
| JP (1) | JP5758399B2 (ref) |
| KR (1) | KR101513784B1 (ref) |
| CN (2) | CN102070618B (ref) |
| AU (1) | AU2010321366B2 (ref) |
| BR (1) | BR112012012138B1 (ref) |
| CA (1) | CA2781066C (ref) |
| DK (1) | DK2504331T3 (ref) |
| ES (1) | ES2529105T3 (ref) |
| IN (1) | IN2012DN04868A (ref) |
| MX (1) | MX2012005926A (ref) |
| MY (1) | MY161749A (ref) |
| NZ (1) | NZ600266A (ref) |
| PH (1) | PH12012500992A1 (ref) |
| PL (1) | PL2504331T3 (ref) |
| PT (1) | PT2504331E (ref) |
| RU (1) | RU2507203C1 (ref) |
| WO (1) | WO2011060746A1 (ref) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102070618B (zh) | 2009-11-23 | 2013-08-21 | 和记黄埔医药（上海）有限公司 | 一种化合物及其晶体 |
| EP3157912B1 (en) * | 2014-06-19 | 2019-02-20 | Merial, Inc. | Parasiticidal compositions comprising indole derivatives, methods and uses thereof |
| CN105985326B (zh) * | 2015-02-16 | 2020-04-14 | 上海宣创生物科技有限公司 | 嘧啶衍生物晶型ⅲ及其制备方法和用途 |
| WO2016187767A1 (en) * | 2015-05-25 | 2016-12-01 | Hutchison Medipharma Limited | Pharmaceutical compositions and use thereof |
| US20190276439A1 (en) * | 2016-11-18 | 2019-09-12 | Hutchison Medipharma Limited | Method of treating solid tumors |
| JP2020164434A (ja) * | 2019-03-28 | 2020-10-08 | 上野製薬株式会社 | ２，６−ナフタレンビス（２−オキサゾリン）の製造方法 |
| CN118593700A (zh) * | 2020-03-09 | 2024-09-06 | 和记黄埔医药（上海）有限公司 | 抗pd-1抗体和多受体酪氨酸激酶抑制剂的药物组合及其使用方法 |
| BR112023021066A2 (pt) * | 2021-04-12 | 2023-12-12 | Mitoimmune Therapeutics Inc | Forma cristalina a, método para preparar a forma cristalina a, composição farmacêutica, e, composição |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0509299A (pt) * | 2004-03-30 | 2007-09-18 | Taisho Pharmaceutical Co Ltd | composto ou um sal, hidrato, ou solvato farmaceuticamente aceitável do mesmo, composição farmacêutica, e, métodos para a profilaxia ou o tratamento de doença, para reduzir ingestão de alimento de um indivìduo, para induzir saciedade em um indivìduo, para controlar ou reduzir ganho de peso em um indivìduo, para modular um receptor de mch em um indivìduo e para produzir uma composição farmacêutica |
| WO2007035309A1 (en) | 2005-09-15 | 2007-03-29 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| SI2154967T1 (sl) * | 2007-04-16 | 2014-06-30 | Hutchison Medipharma Enterprises Limited Offshore Group Chambers | Derivati pirimidina |
| CN101289444B (zh) * | 2007-04-16 | 2012-01-04 | 和记黄埔医药（上海）有限公司 | 一种嘧啶衍生物及其医药用途 |
| TW201008933A (en) * | 2008-08-29 | 2010-03-01 | Hutchison Medipharma Entpr Ltd | Pyrimidine compounds |
| CN102070618B (zh) * | 2009-11-23 | 2013-08-21 | 和记黄埔医药（上海）有限公司 | 一种化合物及其晶体 |
-
2009
- 2009-11-23 CN CN2009101992592A patent/CN102070618B/zh active Active
-
2010
- 2010-11-23 PT PT108311614T patent/PT2504331E/pt unknown
- 2010-11-23 KR KR1020127015836A patent/KR101513784B1/ko active Active
- 2010-11-23 DK DK10831161.4T patent/DK2504331T3/en active
- 2010-11-23 RU RU2012126112/04A patent/RU2507203C1/ru active
- 2010-11-23 MX MX2012005926A patent/MX2012005926A/es active IP Right Grant
- 2010-11-23 PH PH1/2012/500992A patent/PH12012500992A1/en unknown
- 2010-11-23 CA CA2781066A patent/CA2781066C/en active Active
- 2010-11-23 ES ES10831161.4T patent/ES2529105T3/es active Active
- 2010-11-23 WO PCT/CN2010/078997 patent/WO2011060746A1/en not_active Ceased
- 2010-11-23 NZ NZ600266A patent/NZ600266A/en unknown
- 2010-11-23 AU AU2010321366A patent/AU2010321366B2/en active Active
- 2010-11-23 CN CN201080052921.2A patent/CN102648194B/zh active Active
- 2010-11-23 PL PL10831161T patent/PL2504331T3/pl unknown
- 2010-11-23 EP EP10831161.4A patent/EP2504331B1/en active Active
- 2010-11-23 US US13/510,249 patent/US8658658B2/en active Active
- 2010-11-23 IN IN4868DEN2012 patent/IN2012DN04868A/en unknown
- 2010-11-23 BR BR112012012138-3A patent/BR112012012138B1/pt active IP Right Grant
- 2010-11-23 MY MYPI2012002250A patent/MY161749A/en unknown
- 2010-11-23 JP JP2012539175A patent/JP5758399B2/ja active Active
-
2013
- 2013-12-12 US US14/104,954 patent/US8946249B2/en active Active
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