DK241882A - Fremgangsmaade til fremstilling af amider med antihypertensiv og angiotensinomdannende enzymhaemmende virkning - Google Patents

Fremgangsmaade til fremstilling af amider med antihypertensiv og angiotensinomdannende enzymhaemmende virkning Download PDF

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Publication number
DK241882A
DK241882A DK241882A DK241882A DK241882A DK 241882 A DK241882 A DK 241882A DK 241882 A DK241882 A DK 241882A DK 241882 A DK241882 A DK 241882A DK 241882 A DK241882 A DK 241882A
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Prior art keywords
angiotenes
amids
hypertensive
procedure
preparation
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Application number
DK241882A
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Danish (da)
English (en)
Inventor
R D Youssefyeh
H Jones
Original Assignee
Usv Pharma Corp
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Publication date
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Publication of DK241882A publication Critical patent/DK241882A/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • C07C327/20Esters of monothiocarboxylic acids
    • C07C327/32Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • C07C327/20Esters of monothiocarboxylic acids
    • C07C327/32Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C07C327/34Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups with amino groups bound to the same hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C329/00Thiocarbonic acids; Halides, esters or anhydrides thereof
    • C07C329/12Dithiocarbonic acids; Derivatives thereof
    • C07C329/14Esters of dithiocarbonic acids
    • C07C329/16Esters of dithiocarbonic acids having sulfur atoms of dithiocarbonic groups bound to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/02Thiocyanates
    • C07C331/14Thiocyanates having sulfur atoms of thiocyanate groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C333/00Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C333/02Monothiocarbamic acids; Derivatives thereof
    • C07C333/04Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C333/00Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C333/02Monothiocarbamic acids; Derivatives thereof
    • C07C333/08Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C381/00Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
    • C07C381/02Thiosulfates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK241882A 1981-06-01 1982-05-28 Fremgangsmaade til fremstilling af amider med antihypertensiv og angiotensinomdannende enzymhaemmende virkning DK241882A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/269,166 US4507316A (en) 1981-06-01 1981-06-01 Antihypertensive compounds

Publications (1)

Publication Number Publication Date
DK241882A true DK241882A (da) 1982-12-02

Family

ID=23026080

Family Applications (1)

Application Number Title Priority Date Filing Date
DK241882A DK241882A (da) 1981-06-01 1982-05-28 Fremgangsmaade til fremstilling af amider med antihypertensiv og angiotensinomdannende enzymhaemmende virkning

Country Status (10)

Country Link
US (1) US4507316A (de)
EP (1) EP0066254B1 (de)
JP (1) JPS58958A (de)
AU (1) AU8411682A (de)
DE (1) DE3275375D1 (de)
DK (1) DK241882A (de)
ES (1) ES513889A0 (de)
NZ (1) NZ200798A (de)
PH (1) PH19562A (de)
ZA (1) ZA823710B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0284510A3 (de) * 1987-03-24 1990-08-22 Asahi Breweries, Ltd. N-[N-alpha-(1(S)-carboxy-3-cyclohexylpropyl)-L-lysyl]-N-cyclopentylglycin als antihypertensives Mittel
US5292926A (en) * 1988-01-25 1994-03-08 Santen Pharmaceutical Co., Ltd. Cysteine derivatives
JP7074904B1 (ja) 2021-03-16 2022-05-24 東海カーボン株式会社 黒鉛電極、電気炉

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4297295A (en) * 1976-09-17 1981-10-27 Stauffer Chemical Company N-(Benzenesulfonyl) thiocarbamates-herbicidal antidotes
AU4091178A (en) * 1977-10-25 1980-04-24 Merck & Co Inc Substituted mercapto acid amides
FR2447373A1 (fr) * 1979-01-24 1980-08-22 Rhone Poulenc Agrochimie Produits derives de l'aniline ayant une activite antifongique ainsi que leur procede de preparation
US4256761A (en) * 1979-07-13 1981-03-17 Usv Pharmaceutical Corporation Antihypertensive amides
DE2946910A1 (de) * 1979-11-21 1981-07-02 Hoechst Ag, 6230 Frankfurt Fungizide sulfonyl-, bzw. sulfinylacetanilide
ZA811340B (en) * 1980-06-09 1982-03-31 Morton Norwich Products Inc N-(cycloalkyl)amino acid compounds

Also Published As

Publication number Publication date
JPS58958A (ja) 1983-01-06
EP0066254B1 (de) 1987-02-04
ZA823710B (en) 1983-03-30
US4507316A (en) 1985-03-26
DE3275375D1 (en) 1987-03-12
EP0066254A1 (de) 1982-12-08
PH19562A (en) 1986-05-21
ES8307734A1 (es) 1983-08-01
ES513889A0 (es) 1983-08-01
NZ200798A (en) 1986-04-11
AU8411682A (en) 1982-12-09

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