DK24084A - METHOD FOR PREPARING BETA-LACTAMES - Google Patents

METHOD FOR PREPARING BETA-LACTAMES Download PDF

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Publication number
DK24084A
DK24084A DK24084A DK24084A DK24084A DK 24084 A DK24084 A DK 24084A DK 24084 A DK24084 A DK 24084A DK 24084 A DK24084 A DK 24084A DK 24084 A DK24084 A DK 24084A
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DK
Denmark
Prior art keywords
signifies
general formula
formula see
see diagramm
optically uniform
Prior art date
Application number
DK24084A
Other languages
Danish (da)
Other versions
DK24084D0 (en
Inventor
Gerard Schmid
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK24084D0 publication Critical patent/DK24084D0/en
Publication of DK24084A publication Critical patent/DK24084A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

1. A process for the manufacture of optically uniform beta -lactams of the general formula see diagramm : EP0116854,P10,F1 wherein R**1 signifies lower alkanoyl, lower alkoxycarbonyl or benzoyl, R**2 signifies hydrogen, lower alkyl, lower alkanoyl, lower alkoxycarbonyl or cyano, R**3 signifies hydrogen or lower alkyl, B signifies lower alkylidene, lower cycloalkylidene or carbonyl and Z signifies lower 2-alkenyl or 2,4-di(lower alkoxy)benzyl, whereby the residues denoted as lower have a maximum of 7 carbon atoms, and their corresponding optical antipodes, characterized by reacting a salt of a carboxylic acid of the general formula see diagramm : EP0116854,P10,F2 wherein R**1, R**3 have the above significance, in the presence of a reactive derivative of an organic sulphonic acid and a base with an optically uniform compound of the general formula see diagramm : EP0116854,P11,F3 wherein B and Z have the above significance, or the optical antipode thereof.
DK24084A 1983-01-20 1984-01-19 METHOD FOR PREPARING BETA-LACTAMES DK24084A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH32083 1983-01-20

Publications (2)

Publication Number Publication Date
DK24084D0 DK24084D0 (en) 1984-01-19
DK24084A true DK24084A (en) 1984-07-21

Family

ID=4184333

Family Applications (1)

Application Number Title Priority Date Filing Date
DK24084A DK24084A (en) 1983-01-20 1984-01-19 METHOD FOR PREPARING BETA-LACTAMES

Country Status (13)

Country Link
EP (1) EP0116854B1 (en)
JP (1) JPS59137479A (en)
KR (1) KR840007230A (en)
AT (1) ATE37879T1 (en)
AU (1) AU566914B2 (en)
CA (1) CA1251454A (en)
DE (1) DE3474549D1 (en)
DK (1) DK24084A (en)
IE (1) IE56572B1 (en)
IL (1) IL70685A (en)
NZ (1) NZ206831A (en)
PH (1) PH19214A (en)
ZA (1) ZA84292B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK36784A (en) * 1983-02-25 1984-08-26 Hoffmann La Roche PROCEDURE FOR PREPARING CHIRAL ALDEHYDES
DK411384A (en) * 1983-10-03 1985-04-04 Hoffmann La Roche PROCEDURE FOR THE PREPARATION OF AZETIDINE UNDIVERIVES
US5395931A (en) * 1988-06-30 1995-03-07 Merck & Co., Inc. 6-amido-1-methyl-2-(substituted-thio)carbapenems
US5138050A (en) * 1988-06-30 1992-08-11 Merck & Co., Inc. 6-amido-1-methyl carbapenems

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1262128A (en) * 1981-08-27 1989-10-03 Christian N. Hubschwerlen .beta.-lactams
DE3372768D1 (en) * 1982-06-03 1987-09-03 Hoffmann La Roche 1-SULFO-2-OXOAZETIDINE DERIVATIVES
CA1204746A (en) * 1982-08-19 1986-05-20 Hoffmann-La Roche Limited .beta. LACTAMS
DK36784A (en) * 1983-02-25 1984-08-26 Hoffmann La Roche PROCEDURE FOR PREPARING CHIRAL ALDEHYDES

Also Published As

Publication number Publication date
ZA84292B (en) 1984-09-26
PH19214A (en) 1986-02-04
AU2328884A (en) 1984-07-26
DK24084D0 (en) 1984-01-19
NZ206831A (en) 1987-04-30
DE3474549D1 (en) 1988-11-17
EP0116854B1 (en) 1988-10-12
CA1251454A (en) 1989-03-21
IL70685A0 (en) 1984-04-30
IL70685A (en) 1988-09-30
ATE37879T1 (en) 1988-10-15
EP0116854A2 (en) 1984-08-29
JPS59137479A (en) 1984-08-07
IE840114L (en) 1984-07-20
AU566914B2 (en) 1987-11-05
IE56572B1 (en) 1991-09-11
EP0116854A3 (en) 1984-12-05
KR840007230A (en) 1984-12-06

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Legal Events

Date Code Title Description
ATS Application withdrawn
AHB Application shelved due to non-payment