IL70685A0 - Manufacture of beta-lactams - Google Patents
Manufacture of beta-lactamsInfo
- Publication number
- IL70685A0 IL70685A0 IL70685A IL7068584A IL70685A0 IL 70685 A0 IL70685 A0 IL 70685A0 IL 70685 A IL70685 A IL 70685A IL 7068584 A IL7068584 A IL 7068584A IL 70685 A0 IL70685 A0 IL 70685A0
- Authority
- IL
- Israel
- Prior art keywords
- signifies
- general formula
- formula see
- see diagramm
- lactams
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cephalosporin Compounds (AREA)
Abstract
1. A process for the manufacture of optically uniform beta -lactams of the general formula see diagramm : EP0116854,P10,F1 wherein R**1 signifies lower alkanoyl, lower alkoxycarbonyl or benzoyl, R**2 signifies hydrogen, lower alkyl, lower alkanoyl, lower alkoxycarbonyl or cyano, R**3 signifies hydrogen or lower alkyl, B signifies lower alkylidene, lower cycloalkylidene or carbonyl and Z signifies lower 2-alkenyl or 2,4-di(lower alkoxy)benzyl, whereby the residues denoted as lower have a maximum of 7 carbon atoms, and their corresponding optical antipodes, characterized by reacting a salt of a carboxylic acid of the general formula see diagramm : EP0116854,P10,F2 wherein R**1, R**3 have the above significance, in the presence of a reactive derivative of an organic sulphonic acid and a base with an optically uniform compound of the general formula see diagramm : EP0116854,P11,F3 wherein B and Z have the above significance, or the optical antipode thereof.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH32083 | 1983-01-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL70685A0 true IL70685A0 (en) | 1984-04-30 |
IL70685A IL70685A (en) | 1988-09-30 |
Family
ID=4184333
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL70685A IL70685A (en) | 1983-01-20 | 1984-01-13 | Manufacture of beta-lactams |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0116854B1 (en) |
JP (1) | JPS59137479A (en) |
KR (1) | KR840007230A (en) |
AT (1) | ATE37879T1 (en) |
AU (1) | AU566914B2 (en) |
CA (1) | CA1251454A (en) |
DE (1) | DE3474549D1 (en) |
DK (1) | DK24084A (en) |
IE (1) | IE56572B1 (en) |
IL (1) | IL70685A (en) |
NZ (1) | NZ206831A (en) |
PH (1) | PH19214A (en) |
ZA (1) | ZA84292B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK36784A (en) * | 1983-02-25 | 1984-08-26 | Hoffmann La Roche | PROCEDURE FOR PREPARING CHIRAL ALDEHYDES |
DK411384A (en) * | 1983-10-03 | 1985-04-04 | Hoffmann La Roche | PROCEDURE FOR THE PREPARATION OF AZETIDINE UNDIVERIVES |
US5395931A (en) * | 1988-06-30 | 1995-03-07 | Merck & Co., Inc. | 6-amido-1-methyl-2-(substituted-thio)carbapenems |
US5138050A (en) * | 1988-06-30 | 1992-08-11 | Merck & Co., Inc. | 6-amido-1-methyl carbapenems |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1262128A (en) * | 1981-08-27 | 1989-10-03 | Christian N. Hubschwerlen | .beta.-lactams |
EP0096296B1 (en) * | 1982-06-03 | 1987-07-29 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | 1-sulfo-2-oxoazetidine derivatives |
CA1204746A (en) * | 1982-08-19 | 1986-05-20 | Hoffmann-La Roche Limited | .beta. LACTAMS |
DK36784A (en) * | 1983-02-25 | 1984-08-26 | Hoffmann La Roche | PROCEDURE FOR PREPARING CHIRAL ALDEHYDES |
-
1984
- 1984-01-06 CA CA000444812A patent/CA1251454A/en not_active Expired
- 1984-01-13 ZA ZA84292A patent/ZA84292B/en unknown
- 1984-01-13 NZ NZ206831A patent/NZ206831A/en unknown
- 1984-01-13 IL IL70685A patent/IL70685A/en not_active IP Right Cessation
- 1984-01-16 AU AU23288/84A patent/AU566914B2/en not_active Ceased
- 1984-01-17 AT AT84100452T patent/ATE37879T1/en active
- 1984-01-17 EP EP84100452A patent/EP0116854B1/en not_active Expired
- 1984-01-17 DE DE8484100452T patent/DE3474549D1/en not_active Expired
- 1984-01-18 JP JP59005852A patent/JPS59137479A/en active Pending
- 1984-01-19 DK DK24084A patent/DK24084A/en not_active Application Discontinuation
- 1984-01-19 KR KR1019840000230A patent/KR840007230A/en not_active Application Discontinuation
- 1984-01-19 PH PH30129A patent/PH19214A/en unknown
- 1984-01-19 IE IE114/84A patent/IE56572B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP0116854A3 (en) | 1984-12-05 |
KR840007230A (en) | 1984-12-06 |
NZ206831A (en) | 1987-04-30 |
IE840114L (en) | 1984-07-20 |
JPS59137479A (en) | 1984-08-07 |
DE3474549D1 (en) | 1988-11-17 |
DK24084D0 (en) | 1984-01-19 |
EP0116854B1 (en) | 1988-10-12 |
ATE37879T1 (en) | 1988-10-15 |
DK24084A (en) | 1984-07-21 |
IL70685A (en) | 1988-09-30 |
AU566914B2 (en) | 1987-11-05 |
EP0116854A2 (en) | 1984-08-29 |
IE56572B1 (en) | 1991-09-11 |
PH19214A (en) | 1986-02-04 |
CA1251454A (en) | 1989-03-21 |
ZA84292B (en) | 1984-09-26 |
AU2328884A (en) | 1984-07-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM9K | Patent not in force due to non-payment of renewal fees |