DK2396345T3 - Antimikrobielle peptider baseret på cmap27 - Google Patents
Antimikrobielle peptider baseret på cmap27 Download PDFInfo
- Publication number
- DK2396345T3 DK2396345T3 DK10704016.4T DK10704016T DK2396345T3 DK 2396345 T3 DK2396345 T3 DK 2396345T3 DK 10704016 T DK10704016 T DK 10704016T DK 2396345 T3 DK2396345 T3 DK 2396345T3
- Authority
- DK
- Denmark
- Prior art keywords
- cmap27
- peptide
- peptides
- cells
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/465—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (14)
1. CMAP27-derivater, der består af den almene aminosyresekvens RX1GRX2LRKIRRX3X4, hvor Xi, X2 og X3 uafhængigt kan være F, L, W, eller Y og X4 kan være 0-9 aminosyrer.
2. CMAP27-derivat ifølge krav 1, hvor én af Xi, X2 og X3 er F.
3. CMAP27-derivat ifølge krav 1 eller 2, hvor to eller flere af Xi, X2 og X3 er F.
4. CMAP27-derivat ifølge et hvilket som helst af ovenstående krav, hvor X4 er 0 aminosyrer.
5. CMAP27-derivat ifølge et hvilket som helst af kravene 1 -3, hvor X4 er R.
6. CMAP27-derivat ifølge et hvilket som helst af kravene 1-3, hvor X4 er RX5K, RX5KVT eller RXsKYTITIQ, hvor X5 er P, G eller L.
7. CMAP27-derivat ifølge krav 6, hvor X5 er P.
8. CMAP27-derivat ifølge et hvilket som helst af kravene 1 -7 til anvendelse som et medikament.
9. CMAP27-derivat ifølge et hvilket som helst af kravene 1-7 til anvendelse som antibiotikum.
10. Farmaceutisk sammensætning, der omfatter mindst ét CMAP27-derivat ifølge et hvilket som helst af kravene 1 til 7.
11. Anvendelse af et CMAP27-derivat ifølge et hvilket som helst af kravene 1-7 til fremstilling af et medikament til behandling af bakterieinfektioner.
12. Anvendelse af et CMAP27-derivat ifølge et hvilket som helst af kravene 1-7 som antibiotikum.
13. Immunologisk sammensætning, fortrinsvis en vaccinesammensætning, der består af et CMAP27-peptid udvalgt fra gruppen af CMAP27-derivater ifølge krav 1, CMAP27 og CMAP26-NH2.
14. Anvendelse af et CMAP27-peptid udvalgt fra gruppen af CMAP27-derivater ifølge krav 1, CMAP27 og CMAP26-NH2 som adjuvans.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09152810 | 2009-02-13 | ||
| PCT/NL2010/050068 WO2010093245A1 (en) | 2009-02-13 | 2010-02-12 | Antimicrobial peptides based on cmap27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2396345T3 true DK2396345T3 (da) | 2017-02-13 |
Family
ID=40671145
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16197733.5T DK3150627T3 (da) | 2009-02-13 | 2010-02-12 | Antimikrobielle peptider baseret på cmap27 |
| DK10704016.4T DK2396345T3 (da) | 2009-02-13 | 2010-02-12 | Antimikrobielle peptider baseret på cmap27 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16197733.5T DK3150627T3 (da) | 2009-02-13 | 2010-02-12 | Antimikrobielle peptider baseret på cmap27 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US9006174B2 (da) |
| EP (2) | EP2396345B1 (da) |
| DK (2) | DK3150627T3 (da) |
| ES (2) | ES2710785T3 (da) |
| HR (1) | HRP20190262T1 (da) |
| HU (2) | HUE042310T2 (da) |
| PL (2) | PL3150627T3 (da) |
| PT (2) | PT3150627T (da) |
| SI (1) | SI3150627T1 (da) |
| TR (1) | TR201901717T4 (da) |
| WO (1) | WO2010093245A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2948455C (en) | 2014-05-09 | 2023-09-19 | Universiteit Utrecht Holding B.V. | New cath2 derivatives |
| CN107043428A (zh) * | 2017-05-02 | 2017-08-15 | 东北农业大学 | 一种α螺旋结构的抗炎杂合抗菌肽及其制备方法和应用 |
| CN110128544B (zh) * | 2019-04-03 | 2020-12-01 | 中国农业大学 | 一种具有免疫调节和抗炎功能的杂合肽及其制备方法与应用 |
| CA3202622A1 (en) | 2020-12-18 | 2022-06-23 | Hendrik Peter HAAGSMAN | Cath2 derivatives for stimulating innate immune memory |
| KR20230146035A (ko) | 2021-02-05 | 2023-10-18 | 유니버시테이트 우트레크트 홀딩 비.브이. | 스트렙토코커스 수이스를 억제하는 cath2 및 유도체 |
| AR126731A1 (es) * | 2021-08-05 | 2023-11-08 | Zoetis Services Llc | Composiciones y métodos para tratar la mastitis |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007064903A1 (en) * | 2005-12-02 | 2007-06-07 | The Board Of Regents For Oklahoma State University | Fowlicidins and methods of their use |
-
2010
- 2010-02-12 WO PCT/NL2010/050068 patent/WO2010093245A1/en active Application Filing
- 2010-02-12 DK DK16197733.5T patent/DK3150627T3/da active
- 2010-02-12 DK DK10704016.4T patent/DK2396345T3/da active
- 2010-02-12 HU HUE16197733A patent/HUE042310T2/hu unknown
- 2010-02-12 ES ES16197733T patent/ES2710785T3/es active Active
- 2010-02-12 SI SI201031853T patent/SI3150627T1/sl unknown
- 2010-02-12 ES ES10704016.4T patent/ES2613266T3/es active Active
- 2010-02-12 TR TR2019/01717T patent/TR201901717T4/tr unknown
- 2010-02-12 PL PL16197733T patent/PL3150627T3/pl unknown
- 2010-02-12 PL PL10704016T patent/PL2396345T3/pl unknown
- 2010-02-12 EP EP10704016.4A patent/EP2396345B1/en active Active
- 2010-02-12 PT PT16197733T patent/PT3150627T/pt unknown
- 2010-02-12 PT PT107040164T patent/PT2396345T/pt unknown
- 2010-02-12 HU HUE10704016A patent/HUE031681T2/en unknown
- 2010-02-12 EP EP16197733.5A patent/EP3150627B1/en active Active
- 2010-02-12 US US13/201,070 patent/US9006174B2/en active Active
-
2015
- 2015-03-26 US US14/669,228 patent/US10301363B2/en active Active
-
2019
- 2019-02-11 HR HRP20190262TT patent/HRP20190262T1/hr unknown
- 2019-04-10 US US16/380,790 patent/US11186619B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20150197547A1 (en) | 2015-07-16 |
| HRP20190262T1 (hr) | 2019-04-05 |
| TR201901717T4 (tr) | 2019-03-21 |
| DK3150627T3 (da) | 2019-03-11 |
| EP3150627A1 (en) | 2017-04-05 |
| US9006174B2 (en) | 2015-04-14 |
| SI3150627T1 (sl) | 2019-03-29 |
| ES2710785T3 (es) | 2019-04-26 |
| EP2396345B1 (en) | 2016-11-09 |
| PT2396345T (pt) | 2017-02-10 |
| EP2396345A1 (en) | 2011-12-21 |
| ES2613266T3 (es) | 2017-05-23 |
| HUE042310T2 (hu) | 2019-06-28 |
| US11186619B2 (en) | 2021-11-30 |
| US20190233483A1 (en) | 2019-08-01 |
| WO2010093245A1 (en) | 2010-08-19 |
| HUE031681T2 (en) | 2017-08-28 |
| US20120093844A1 (en) | 2012-04-19 |
| EP3150627B1 (en) | 2018-11-21 |
| PL2396345T3 (pl) | 2017-06-30 |
| PL3150627T3 (pl) | 2019-05-31 |
| US10301363B2 (en) | 2019-05-28 |
| PT3150627T (pt) | 2019-02-18 |
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