TR201901717T4 - CMAP27 ye dayalı antimikrobiyal peptidler. - Google Patents

CMAP27 ye dayalı antimikrobiyal peptidler. Download PDF

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Publication number
TR201901717T4
TR201901717T4 TR2019/01717T TR201901717T TR201901717T4 TR 201901717 T4 TR201901717 T4 TR 201901717T4 TR 2019/01717 T TR2019/01717 T TR 2019/01717T TR 201901717 T TR201901717 T TR 201901717T TR 201901717 T4 TR201901717 T4 TR 201901717T4
Authority
TR
Turkey
Prior art keywords
cmap27
derivatives
antimicrobial peptides
peptides based
adjuvants
Prior art date
Application number
TR2019/01717T
Other languages
English (en)
Inventor
Jacob Bikker Floris
Van Dijk Albert
Mars-Groenendijk Rosalia
Johannes Adrianus Veldhuizen Edwin
Van Der Kleij Desiree
Haagsman Hendrik
Margaretha Molhoek Elisabeth
Original Assignee
Univ Utrecht Holding Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Utrecht Holding Bv filed Critical Univ Utrecht Holding Bv
Publication of TR201901717T4 publication Critical patent/TR201901717T4/tr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/465—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from birds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides

Abstract

Buluş, doğal suş CMAP27 peptidi ile karşılaştırıldığında iyi bir antimikrobiyel aktivite ve düşük bir hemolitik aktiviteye sahip olan CMAP27 deriveleri ile ilgilidir. Bu deriveler antibiyotik terapiye yönelik veya bir bakterisidal bileşimde kullanılabilir. Buluşta ayrıca CMAP27 ve/veya bunun derivelerinin adjuvan olarak kullanımı kapsanır.
TR2019/01717T 2009-02-13 2010-02-12 CMAP27 ye dayalı antimikrobiyal peptidler. TR201901717T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09152810 2009-02-13

Publications (1)

Publication Number Publication Date
TR201901717T4 true TR201901717T4 (tr) 2019-03-21

Family

ID=40671145

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/01717T TR201901717T4 (tr) 2009-02-13 2010-02-12 CMAP27 ye dayalı antimikrobiyal peptidler.

Country Status (11)

Country Link
US (3) US9006174B2 (tr)
EP (2) EP2396345B1 (tr)
DK (2) DK3150627T3 (tr)
ES (2) ES2710785T3 (tr)
HR (1) HRP20190262T1 (tr)
HU (2) HUE042310T2 (tr)
PL (2) PL3150627T3 (tr)
PT (2) PT3150627T (tr)
SI (1) SI3150627T1 (tr)
TR (1) TR201901717T4 (tr)
WO (1) WO2010093245A1 (tr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2948455C (en) 2014-05-09 2023-09-19 Universiteit Utrecht Holding B.V. New cath2 derivatives
CN107043428A (zh) * 2017-05-02 2017-08-15 东北农业大学 一种α螺旋结构的抗炎杂合抗菌肽及其制备方法和应用
CN110128544B (zh) * 2019-04-03 2020-12-01 中国农业大学 一种具有免疫调节和抗炎功能的杂合肽及其制备方法与应用
CA3202622A1 (en) 2020-12-18 2022-06-23 Hendrik Peter HAAGSMAN Cath2 derivatives for stimulating innate immune memory
KR20230146035A (ko) 2021-02-05 2023-10-18 유니버시테이트 우트레크트 홀딩 비.브이. 스트렙토코커스 수이스를 억제하는 cath2 및 유도체
AR126731A1 (es) * 2021-08-05 2023-11-08 Zoetis Services Llc Composiciones y métodos para tratar la mastitis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007064903A1 (en) * 2005-12-02 2007-06-07 The Board Of Regents For Oklahoma State University Fowlicidins and methods of their use

Also Published As

Publication number Publication date
US20150197547A1 (en) 2015-07-16
HRP20190262T1 (hr) 2019-04-05
DK3150627T3 (en) 2019-03-11
EP3150627A1 (en) 2017-04-05
US9006174B2 (en) 2015-04-14
SI3150627T1 (sl) 2019-03-29
ES2710785T3 (es) 2019-04-26
EP2396345B1 (en) 2016-11-09
DK2396345T3 (en) 2017-02-13
PT2396345T (pt) 2017-02-10
EP2396345A1 (en) 2011-12-21
ES2613266T3 (es) 2017-05-23
HUE042310T2 (hu) 2019-06-28
US11186619B2 (en) 2021-11-30
US20190233483A1 (en) 2019-08-01
WO2010093245A1 (en) 2010-08-19
HUE031681T2 (en) 2017-08-28
US20120093844A1 (en) 2012-04-19
EP3150627B1 (en) 2018-11-21
PL2396345T3 (pl) 2017-06-30
PL3150627T3 (pl) 2019-05-31
US10301363B2 (en) 2019-05-28
PT3150627T (pt) 2019-02-18

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