DK2266557T3 - Kombination af benzophenonderivat eller salt deraf og immunosuppressivt stof, samt farmaceutisk sammensætning omfattede disse komponenter - Google Patents

Kombination af benzophenonderivat eller salt deraf og immunosuppressivt stof, samt farmaceutisk sammensætning omfattede disse komponenter

Info

Publication number
DK2266557T3
DK2266557T3 DK09735250.4T DK09735250T DK2266557T3 DK 2266557 T3 DK2266557 T3 DK 2266557T3 DK 09735250 T DK09735250 T DK 09735250T DK 2266557 T3 DK2266557 T3 DK 2266557T3
Authority
DK
Denmark
Prior art keywords
immunosuppressant
comprised
salt
combination
components
Prior art date
Application number
DK09735250.4T
Other languages
English (en)
Inventor
Yukihiko Aikawa
Shunichi Shiozawa
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Application granted granted Critical
Publication of DK2266557T3 publication Critical patent/DK2266557T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK09735250.4T 2008-04-22 2009-04-20 Kombination af benzophenonderivat eller salt deraf og immunosuppressivt stof, samt farmaceutisk sammensætning omfattede disse komponenter DK2266557T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2008111295 2008-04-22
PCT/JP2009/057860 WO2009131098A1 (ja) 2008-04-22 2009-04-20 ベンゾフェノン誘導体またはその塩および免疫抑制剤を組み合わせて使用する方法ならびにこれらを含有する医薬組成物

Publications (1)

Publication Number Publication Date
DK2266557T3 true DK2266557T3 (da) 2013-09-23

Family

ID=41216830

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09735250.4T DK2266557T3 (da) 2008-04-22 2009-04-20 Kombination af benzophenonderivat eller salt deraf og immunosuppressivt stof, samt farmaceutisk sammensætning omfattede disse komponenter

Country Status (21)

Country Link
US (1) US9066977B2 (da)
EP (1) EP2266557B1 (da)
JP (2) JP5512511B2 (da)
KR (1) KR101525851B1 (da)
CN (2) CN102920711A (da)
AU (1) AU2009239053B2 (da)
BR (1) BRPI0910735A2 (da)
CA (1) CA2721920A1 (da)
CY (1) CY1114378T1 (da)
DK (1) DK2266557T3 (da)
ES (1) ES2429592T3 (da)
HR (1) HRP20130859T1 (da)
IL (1) IL208622A0 (da)
MX (1) MX2010011666A (da)
NZ (1) NZ588470A (da)
PL (1) PL2266557T3 (da)
PT (1) PT2266557E (da)
RU (1) RU2496490C2 (da)
SI (1) SI2266557T1 (da)
WO (1) WO2009131098A1 (da)
ZA (1) ZA201007133B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100240891A1 (en) 2007-09-28 2010-09-23 Toyama Chemical Co., Ltd. Drug containing benzophenone derivative or its salt
US10537585B2 (en) 2017-12-18 2020-01-21 Dexcel Pharma Technologies Ltd. Compositions comprising dexamethasone
CN118255728B (zh) * 2024-01-25 2024-07-30 中国医学科学院阜外医院 化合物的盐型晶型用于治疗射血分数保留的心衰的用途
CN118252824B (zh) * 2024-01-25 2024-09-17 中国医学科学院阜外医院 化合物用于治疗射血分数保留的心衰的用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL353639A1 (en) 1999-07-16 2003-12-01 Leo Pharma A/Sleo Pharma A/S Aminobenzophenones as inhibitors of il-1beta and tnf-alpha
EP1289958A2 (en) * 2000-05-22 2003-03-12 Leo Pharma A/S BENZOPHENONES AS INHIBITORS OF IL-1$g(b) AND TNF-$g(a)
US6608101B1 (en) 2000-06-20 2003-08-19 Atherogenics, Inc. 1, 3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat VCAM-1 mediated disorders
JP2003040776A (ja) 2001-05-24 2003-02-13 Sankyo Co Ltd 関節炎を予防若しくは治療するための医薬組成物
HUP0402025A3 (en) * 2001-11-16 2006-01-30 Shiozawa Shunichi Kobe Shi Novel bensophenone derivatives or salts thereof and their use
TW200500065A (en) 2003-05-21 2005-01-01 Wyeth Corp Antiarthritic combinations
SI1988085T1 (sl) 2006-02-21 2015-03-31 Toyama Chemical Co., Ltd. Postopek za izdelavo 3-(5-(4-(ciklopentiloksi)-2-hidroksibenzoil)-2-((3 -hidroksi-1,2-benzizoksazol-6-il)metoksi)fenil)propionat estra in intermediata za ta postopek
WO2007138996A1 (ja) 2006-05-26 2007-12-06 Toyama Chemical Co., Ltd. ３－｛５－［４－（シクロペンチルオキシ）－２－ヒドロキシベンゾイル］－２－［（３－ヒドロキシ－１，２－ベンズイソオキサゾール－６－イル）メトキシ］フェニル｝プロピオン酸の新規な結晶
EP2022497B1 (en) * 2006-05-26 2014-04-30 Toyama Chemical Co., Ltd. Oral composition comprising 3-[5-[4-(cyclopentyloxy) -2-hydroxybenzoyl]-2-](3-hydroxy-1,2-benzisoxazol-6- yl)methoxy¨phenyl¨propionic acid or salt thereof
US20100240891A1 (en) 2007-09-28 2010-09-23 Toyama Chemical Co., Ltd. Drug containing benzophenone derivative or its salt

Also Published As

Publication number Publication date
EP2266557A4 (en) 2011-09-21
CN102920711A (zh) 2013-02-13
MX2010011666A (es) 2010-12-06
ZA201007133B (en) 2011-12-28
IL208622A0 (en) 2010-12-30
AU2009239053B2 (en) 2014-04-03
JPWO2009131098A1 (ja) 2011-08-18
NZ588470A (en) 2012-12-21
CN102014889A (zh) 2011-04-13
PT2266557E (pt) 2013-09-30
CY1114378T1 (el) 2016-08-31
BRPI0910735A2 (pt) 2019-09-24
WO2009131098A1 (ja) 2009-10-29
EP2266557B1 (en) 2013-08-14
JP5698830B2 (ja) 2015-04-08
US9066977B2 (en) 2015-06-30
US20110039813A1 (en) 2011-02-17
RU2010147396A (ru) 2012-05-27
JP5512511B2 (ja) 2014-06-04
HRP20130859T1 (hr) 2013-10-11
RU2496490C2 (ru) 2013-10-27
CA2721920A1 (en) 2009-10-29
AU2009239053A1 (en) 2009-10-29
PL2266557T3 (pl) 2013-12-31
KR101525851B1 (ko) 2015-06-04
JP2014166984A (ja) 2014-09-11
ES2429592T3 (es) 2013-11-15
KR20110025167A (ko) 2011-03-09
EP2266557A1 (en) 2010-12-29
SI2266557T1 (sl) 2013-12-31

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