DK2225228T3 - Fremgangsmåde til opnåelse af 4-n-furfurylcytosin og/eller dets derivater, en anti-aldrings-sammensætning og anvendelse af 4-n-furfurylcytosin og/eller dets derivater i fremstillingen af en anti- aldrings-sammensætning - Google Patents

Fremgangsmåde til opnåelse af 4-n-furfurylcytosin og/eller dets derivater, en anti-aldrings-sammensætning og anvendelse af 4-n-furfurylcytosin og/eller dets derivater i fremstillingen af en anti- aldrings-sammensætning Download PDF

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Publication number
DK2225228T3
DK2225228T3 DK08851400.5T DK08851400T DK2225228T3 DK 2225228 T3 DK2225228 T3 DK 2225228T3 DK 08851400 T DK08851400 T DK 08851400T DK 2225228 T3 DK2225228 T3 DK 2225228T3
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DK
Denmark
Prior art keywords
derivatives
preparation
cells
furfurylyctosin
furfurylcytosine
Prior art date
Application number
DK08851400.5T
Other languages
English (en)
Inventor
Jan Barciszewski
Wojciech T Markiewicz
Eliza Wyszko
Maria Markiewicz
Monika Nowak
Katarzyna Rolle
Ewelina Adamska
Marcin K Chmielewski
Original Assignee
Inst Chemii Bioorganicznej Pan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Inst Chemii Bioorganicznej Pan filed Critical Inst Chemii Bioorganicznej Pan
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Publication of DK2225228T3 publication Critical patent/DK2225228T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Saccharide Compounds (AREA)

Claims (4)

1. Anti-aldrings-sammensætning, kendetegnet ved at den indeholder 4-N-furfurylcytosin og/eller dets derivater, med den almene formel.
hvor: Ri, R2, R3 = H eller alkyl, alkenyl, alkinyl, hydroxyalkyl eller aryl R4, Rs, Rs = H eller alkyl R7, Rs = H, CH3, alkyl, alkenyl, alkinyl, hydroxyalkyl Rg = H, D-2-deoxyribosid, D-ribosid, tetrahydropyranyl.
2. Sammensætning ifølge krav 1, kendetegnet ved at 4-N-furfurylcytosin og/eller dets derivat-indhold i sammensætningen er op til 2%.
3. Anvendelse af 4-N-furfurylcytosin og/eller dets derivater, med en almen formel
hvor: Ri, R2, R3 - H eller alkyl, alkenyl, alkinyl, hydroxyalkyl eller aryl R4, Rs, R6 = H eller alkyl R.7, Rs = H, CH3, alkyl, alkenyl, alkinyl, hydroxyalkyl R9 = H, D-2-deoxyribosid, D-ribosid, tetrahydropyranyl, i fremstillingen af anti-aldrings-sammensætninger.
4. Anvendelse ifølge krav 3, kendetegnet ved at 4-N-furfurylcytosinet og/eller dets derivat-indhold i anti-aldrings-sammensætninger op til 2%.
DK08851400.5T 2007-11-25 2008-11-25 Fremgangsmåde til opnåelse af 4-n-furfurylcytosin og/eller dets derivater, en anti-aldrings-sammensætning og anvendelse af 4-n-furfurylcytosin og/eller dets derivater i fremstillingen af en anti- aldrings-sammensætning DK2225228T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PL383867A PL216370B1 (pl) 2007-11-25 2007-11-25 Sposób otrzymywania 4-N-furfurylocytozyny, kompozycja antystarzeniowa oraz zastosowanie 4-N-furfurylocytozyny do wytwarzania kompozycji antystarzeniowej
PCT/PL2008/000089 WO2009067035A2 (en) 2007-11-25 2008-11-25 Method of obtaining of 4-n-furfurylcytosine and/or its derivatives, an anti-aging composition and use of 4-n-furfurylcytosine and/or its derivatives in the manufacture of anti-aging composition

Publications (1)

Publication Number Publication Date
DK2225228T3 true DK2225228T3 (da) 2017-01-16

Family

ID=40568369

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08851400.5T DK2225228T3 (da) 2007-11-25 2008-11-25 Fremgangsmåde til opnåelse af 4-n-furfurylcytosin og/eller dets derivater, en anti-aldrings-sammensætning og anvendelse af 4-n-furfurylcytosin og/eller dets derivater i fremstillingen af en anti- aldrings-sammensætning

Country Status (6)

Country Link
US (1) US8404660B2 (da)
EP (1) EP2225228B1 (da)
DK (1) DK2225228T3 (da)
ES (1) ES2610209T3 (da)
PL (2) PL216370B1 (da)
WO (1) WO2009067035A2 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL229581B1 (pl) 2010-03-19 2018-08-31 Inst Chemii Bioorganicznej Polskiej Akademii Nauk Analog cytozyny i jego zastosowanie w leczeniu chorób związanych z zaburzeniami metylacji DNA

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU193318B (en) * 1985-06-12 1987-09-28 Richter Gedeon Vegyeszet Process for producing new bis- indol derivatives
CA1339503C (en) * 1987-02-26 1997-10-21 Suresh I.S. Rattan Method and composition for ameliorating the adverse effects of aging
US5021422A (en) 1989-06-08 1991-06-04 Senetek Plc Method and composition for treating hyperproliferative skin diseases using 6-aminopurine cytokinins
US5164394A (en) 1989-06-08 1992-11-17 Senetek, Plc Method for treating hyperproliferative skin diseases
JP2000319184A (ja) 1991-05-16 2000-11-21 Senetek Plc 皮膚の美的外観を改善するための方法
US5151425A (en) * 1991-06-20 1992-09-29 Clark Lealand L Method of and composition for treating inflammation and the immunological response thereto
DE4323615A1 (de) 1993-07-12 1995-01-19 Schreiner Edelgard Mittel gegen vorzeitiges Altern der Haut
GB9825687D0 (en) * 1998-11-25 1999-01-20 Link Technologies Ltd Oligonucleotide conjugation
KR100332031B1 (ko) 1999-06-03 2002-04-10 서경배 피부 주름의 개선 및 생성 억제 효과를 갖는 외용제 조성물
JP2001031549A (ja) 1999-07-14 2001-02-06 Pola Chem Ind Inc 真皮コラーゲン線維束再構築剤及びそれを含有する化粧料
WO2005020885A2 (en) * 2003-05-21 2005-03-10 Isis Pharmaceuticals, Inc. Compositions and methods for the treatment of severe acute respiratory syndrome (sars)
US20090023672A1 (en) * 2005-01-27 2009-01-22 Kurume University Age-2 aptamer

Also Published As

Publication number Publication date
PL383867A1 (pl) 2009-06-08
PL2225228T3 (pl) 2017-10-31
US20100317612A1 (en) 2010-12-16
WO2009067035A3 (en) 2009-09-24
WO2009067035A2 (en) 2009-05-28
PL216370B1 (pl) 2014-03-31
US8404660B2 (en) 2013-03-26
EP2225228B1 (en) 2016-10-12
EP2225228A2 (en) 2010-09-08
ES2610209T3 (es) 2017-04-26

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