DK2088A - 11beta-alkinyloestrener og -oestradiner, deres fremstilling og farmaceutiske praeparater indeholdende dem - Google Patents
11beta-alkinyloestrener og -oestradiner, deres fremstilling og farmaceutiske praeparater indeholdende demInfo
- Publication number
- DK2088A DK2088A DK002088A DK2088A DK2088A DK 2088 A DK2088 A DK 2088A DK 002088 A DK002088 A DK 002088A DK 2088 A DK2088 A DK 2088A DK 2088 A DK2088 A DK 2088A
- Authority
- DK
- Denmark
- Prior art keywords
- phenyl
- alkyl
- optionally substituted
- substituted
- estradines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0096—Alkynyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/001—Lactones
- C07J21/003—Lactones at position 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Liquid Crystal Substances (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19873702383 DE3702383A1 (de) | 1987-01-23 | 1987-01-23 | 11ss-alkinylestrene und -estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate |
Publications (2)
Publication Number | Publication Date |
---|---|
DK2088D0 DK2088D0 (da) | 1988-01-05 |
DK2088A true DK2088A (da) | 1988-07-24 |
Family
ID=6319636
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK002088A DK2088A (da) | 1987-01-23 | 1988-01-05 | 11beta-alkinyloestrener og -oestradiner, deres fremstilling og farmaceutiske praeparater indeholdende dem |
Country Status (15)
Country | Link |
---|---|
US (1) | US4870069A (pt) |
EP (1) | EP0277089B1 (pt) |
JP (1) | JPS63201197A (pt) |
AT (1) | ATE64399T1 (pt) |
AU (1) | AU616395B2 (pt) |
CA (1) | CA1326014C (pt) |
DE (2) | DE3702383A1 (pt) |
DK (1) | DK2088A (pt) |
ES (1) | ES2038783T3 (pt) |
GR (1) | GR3002110T3 (pt) |
IE (1) | IE60321B1 (pt) |
NO (1) | NO169344C (pt) |
NZ (1) | NZ223269A (pt) |
PT (1) | PT86591B (pt) |
ZA (1) | ZA88464B (pt) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3633244A1 (de) * | 1986-09-26 | 1988-03-31 | Schering Ag | Antigestagene zur hemmung der uterinen prostaglandinsynthese |
DE3921059A1 (de) * | 1989-06-23 | 1991-01-10 | Schering Ag | 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel |
DE4042007A1 (de) * | 1990-12-22 | 1992-06-25 | Schering Ag | 6,7-modifizierte-11(beta)-aryl-4-estrene |
EP0496520A1 (en) * | 1991-01-22 | 1992-07-29 | Merck & Co. Inc. | Novel bone acting agents |
MX9301121A (es) | 1992-03-02 | 1993-09-01 | Schering Ag | Metodo y equipo para la contracepcion oral y regulacion de la menstruacion con estrogeno/progestina/aniprogestina. |
CA2100514C (en) * | 1992-07-29 | 2005-03-29 | Johannes A. M. Hamersma | 17-spiromethylene steroids |
ZA94715B (en) * | 1993-02-08 | 1994-10-24 | Akzo Nv | Steroids for treating menopausal complaints |
US6037339A (en) * | 1993-02-08 | 2000-03-14 | Akzo Nobel N.V. | C-11 substituted steroids for treating menopausal complaints |
US5710144A (en) * | 1993-02-08 | 1998-01-20 | Akzo Nobel N.V. | C-11 substituted steroids for treating menopausal complaints |
US6407082B1 (en) * | 1996-09-13 | 2002-06-18 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of a vitamin D compound |
US6765002B2 (en) | 2000-03-21 | 2004-07-20 | Gustavo Rodriguez | Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium |
US6034074A (en) | 1996-09-13 | 2000-03-07 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of a Vitamin D compound |
US6511970B1 (en) | 1996-09-13 | 2003-01-28 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium |
US6028064A (en) | 1996-09-13 | 2000-02-22 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of progestin products |
US6090798A (en) * | 1997-12-19 | 2000-07-18 | Alcon Laboratories, Inc. | Treatment of GLC1A glaucoma with glucocorticoid antagonists |
US6020328A (en) * | 1998-03-06 | 2000-02-01 | Research Triangle Institute | 20-keto-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties |
US6262042B1 (en) | 1998-05-29 | 2001-07-17 | Research Triangle Institute | 17β-amino and hydroxylamino-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties |
US5962444A (en) * | 1998-05-29 | 1999-10-05 | Research Triangle Institute | 17β-nitro-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties |
US20010044431A1 (en) * | 2000-03-21 | 2001-11-22 | Rodriguez Gustavo C. | Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium |
DE102007063500A1 (de) | 2007-12-29 | 2009-07-02 | Bayer Schering Pharma Aktiengesellschaft | 17-(1'-Propenyl)-17-3'-oxidoestra-4-en-3-on-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel |
DE102007063499A1 (de) * | 2007-12-29 | 2009-07-02 | Bayer Schering Pharma Aktiengesellschaft | Steroid-17,17-Lactol-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel |
DE102007063496A1 (de) * | 2007-12-29 | 2009-07-02 | Bayer Schering Pharma Aktiengesellschaft | 15,16-Methylen-17-(1'-propenyl)-17-3'-oxidoestra-4-en-3-on-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel |
DE102007063498A1 (de) * | 2007-12-29 | 2009-07-02 | Bayer Schering Pharma Aktiengesellschaft | 15,16-Methylen-steroid-17,17-Lactol-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3236866A (en) * | 1959-04-08 | 1966-02-22 | Syntex Corp | 21, 21-difluoro pregnenes |
FR2377418A1 (fr) * | 1977-01-13 | 1978-08-11 | Roussel Uclaf | Nouveaux derives steroides 4,9-dieniques 11b-substitues, leur procede de preparation et leur application comme medicaments |
NL7701384A (nl) * | 1977-02-10 | 1978-08-14 | Akzo Nv | Werkwijze voor het bereiden van nieuwe steroiden van de oestraanreeks. |
DE3410880A1 (de) * | 1984-03-21 | 1985-10-03 | Schering AG, Berlin und Bergkamen, 1000 Berlin | 17-substituierte estradiene und estratriene |
-
1987
- 1987-01-23 DE DE19873702383 patent/DE3702383A1/de not_active Withdrawn
-
1988
- 1988-01-05 DK DK002088A patent/DK2088A/da not_active Application Discontinuation
- 1988-01-21 PT PT86591A patent/PT86591B/pt not_active IP Right Cessation
- 1988-01-22 ES ES198888730017T patent/ES2038783T3/es not_active Expired - Lifetime
- 1988-01-22 CA CA000557191A patent/CA1326014C/en not_active Expired - Fee Related
- 1988-01-22 EP EP88730017A patent/EP0277089B1/de not_active Expired - Lifetime
- 1988-01-22 ZA ZA88464A patent/ZA88464B/xx unknown
- 1988-01-22 DE DE8888730017T patent/DE3863182D1/de not_active Expired - Lifetime
- 1988-01-22 AT AT88730017T patent/ATE64399T1/de not_active IP Right Cessation
- 1988-01-22 NO NO880267A patent/NO169344C/no unknown
- 1988-01-22 JP JP63011036A patent/JPS63201197A/ja active Pending
- 1988-01-25 US US07/147,475 patent/US4870069A/en not_active Expired - Fee Related
- 1988-01-25 IE IE17188A patent/IE60321B1/en not_active IP Right Cessation
- 1988-01-26 NZ NZ223269A patent/NZ223269A/xx unknown
- 1988-01-27 AU AU11114/88A patent/AU616395B2/en not_active Ceased
-
1991
- 1991-07-03 GR GR90401114T patent/GR3002110T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU1111488A (en) | 1988-07-28 |
NO880267D0 (no) | 1988-01-22 |
JPS63201197A (ja) | 1988-08-19 |
PT86591B (pt) | 1991-12-31 |
ES2038783T3 (es) | 1993-08-01 |
DE3863182D1 (de) | 1991-07-18 |
IE880171L (en) | 1988-07-23 |
AU616395B2 (en) | 1991-10-31 |
NO169344C (no) | 1992-06-10 |
NO169344B (no) | 1992-03-02 |
NO880267L (no) | 1988-07-25 |
NZ223269A (en) | 1990-09-26 |
CA1326014C (en) | 1994-01-11 |
PT86591A (pt) | 1988-02-01 |
EP0277089A1 (de) | 1988-08-03 |
GR3002110T3 (en) | 1992-12-30 |
ZA88464B (en) | 1988-09-28 |
US4870069A (en) | 1989-09-26 |
DE3702383A1 (de) | 1988-08-04 |
IE60321B1 (en) | 1994-06-29 |
DK2088D0 (da) | 1988-01-05 |
EP0277089B1 (de) | 1991-06-12 |
ATE64399T1 (de) | 1991-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |