DK2066627T3 - Nye mindre fure (minor groove) bindemidler - Google Patents
Nye mindre fure (minor groove) bindemidlerInfo
- Publication number
- DK2066627T3 DK2066627T3 DK07823959.7T DK07823959T DK2066627T3 DK 2066627 T3 DK2066627 T3 DK 2066627T3 DK 07823959 T DK07823959 T DK 07823959T DK 2066627 T3 DK2066627 T3 DK 2066627T3
- Authority
- DK
- Denmark
- Prior art keywords
- binding agents
- minor groove
- new less
- less fur
- fur
- Prior art date
Links
- 239000011230 binding agent Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0619325.4A GB0619325D0 (en) | 2006-09-30 | 2006-09-30 | New compounds |
| PCT/GB2007/003698 WO2008038018A1 (en) | 2006-09-30 | 2007-09-28 | Novel minor groove binders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2066627T3 true DK2066627T3 (da) | 2014-01-27 |
Family
ID=37434989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07823959.7T DK2066627T3 (da) | 2006-09-30 | 2007-09-28 | Nye mindre fure (minor groove) bindemidler |
Country Status (10)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9072535B2 (en) | 2011-05-27 | 2015-07-07 | Ethicon Endo-Surgery, Inc. | Surgical stapling instruments with rotatable staple deployment arrangements |
| WO2011150156A2 (en) | 2010-05-26 | 2011-12-01 | Sunovion Pharmaceuticals Inc. | Heteroaryl compounds and methods of use thereof |
| CZ305332B6 (cs) * | 2013-10-25 | 2015-08-05 | Univerzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové | Použití derivátů pyrazinu a jejich isosterů jako sloučenin vážících se do malého žlábku DNA |
| CN105732583B (zh) * | 2016-03-25 | 2018-05-04 | 苏州麦迪耐斯医药科技有限公司 | 一种治疗脑胶质母细胞瘤的靶向化合物 |
| JP7072557B2 (ja) | 2016-07-22 | 2022-05-20 | ブリストル－マイヤーズ スクイブ カンパニー | グルコキナーゼ活性化剤およびその使用方法 |
| WO2018047148A1 (en) | 2016-09-12 | 2018-03-15 | Novartis Ag | Compounds for the inhibition of mirna |
| JP7477858B2 (ja) * | 2020-03-05 | 2024-05-02 | 国立大学法人電気通信大学 | 急性ｔリンパ芽球性白血病若しくはリンパ腫、又は急性骨髄性白血病治療用医薬組成物 |
| GB202114032D0 (en) | 2021-09-30 | 2021-11-17 | Univ Strathclyde | Antivirals |
| GB202206931D0 (en) | 2022-05-12 | 2022-06-29 | Univ Strathclyde | Compounds |
| CN115109113B (zh) * | 2022-05-31 | 2023-06-27 | 上海应用技术大学 | 一种胆固醇类衍生物有机凝胶因子及其制备方法和应用 |
| CN116514698A (zh) * | 2023-04-10 | 2023-08-01 | 佛山奕安赛医药科技有限公司 | 一种沃诺拉赞中间体的制备方法及其应用 |
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| DE2331444A1 (de) | 1973-06-20 | 1975-01-23 | Hoechst Ag | Neue styryl-benzoxazole, verfahren zu deren herstellung und ihre verwendung als optische aufhellungsmittel |
| US4665181A (en) | 1984-05-17 | 1987-05-12 | Pennwalt Corporation | Anti-inflammatory phthalazinones |
| CA1308516C (en) | 1987-07-06 | 1992-10-06 | J. William Lown | Oligopeptide anticancer and antiviral agents |
| IL90337A0 (en) | 1988-05-24 | 1989-12-15 | Pfizer | Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents |
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| GB9516943D0 (en) | 1995-08-18 | 1995-10-18 | Cancer Soc Auckland Div Nz Inc | Novel cyclopropylindoles and their secoprecursors,and their use as prodrugs |
| AU1596097A (en) | 1996-02-02 | 1997-08-22 | Pharmacia & Upjohn S.P.A. | Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
| AU734715B2 (en) | 1996-02-26 | 2001-06-21 | California Institute Of Technology | Improved polyamides for binding in the minor groove of double stranded DNA |
| US6506906B1 (en) | 1996-02-26 | 2003-01-14 | California Institute Of Technology | Preparation and use of bifunctional molecules having DNA sequence binding specificity |
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| US6090947A (en) | 1996-02-26 | 2000-07-18 | California Institute Of Technology | Method for the synthesis of pyrrole and imidazole carboxamides on a solid support |
| US6635417B1 (en) | 1996-07-31 | 2003-10-21 | California Institute Of Technology | Complex formation between DSDNA and oligomer of cyclic heterocycles |
| US5770617A (en) | 1996-03-20 | 1998-06-23 | Rutgers, The State University Of New Jersey | Terbenzimidazoles useful as antifungal agents |
| WO1997045411A1 (en) | 1996-05-31 | 1997-12-04 | The Scripps Research Institute | Analogs of cc-1065 and the duocarmycins |
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| WO2003070450A1 (fr) | 2002-02-21 | 2003-08-28 | Riken | Film d'acide polyhydroxyalcanoique haute resistance et procede de production associe |
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| WO2003078450A2 (en) | 2002-03-11 | 2003-09-25 | Epoch Biosciences, Inc. | Negatively charged minor groove binders |
| BRPI0408876A (pt) | 2003-07-30 | 2006-04-11 | Kyowa Hakko Kogyo Kk | derivado de indazol, composição farmacêutica, agentes anti-tumoral e terapêutico, uso do derivado de indazol ou do seu sal farmaceuticamente aceitável, e, métodos para tratar de tumor, para tratar de leucemia, para tratar de mieloma ou linfoma, para tratar de carcinoma sólido e para tratar de cáncer |
-
2006
- 2006-09-30 GB GBGB0619325.4A patent/GB0619325D0/en not_active Ceased
-
2007
- 2007-09-28 EP EP07823959.7A patent/EP2066627B1/en active Active
- 2007-09-28 ES ES07823959.7T patent/ES2443720T3/es active Active
- 2007-09-28 CA CA2664847A patent/CA2664847C/en active Active
- 2007-09-28 US US12/443,529 patent/US8012967B2/en active Active
- 2007-09-28 DK DK07823959.7T patent/DK2066627T3/da active
- 2007-09-28 GB GB0906908A patent/GB2455479C/en not_active Expired - Fee Related
- 2007-09-28 PL PL07823959T patent/PL2066627T3/pl unknown
- 2007-09-28 CN CN200780043350.4A patent/CN101589024B/zh active Active
- 2007-09-28 JP JP2009529767A patent/JP5564257B2/ja active Active
- 2007-09-28 WO PCT/GB2007/003698 patent/WO2008038018A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| JP5564257B2 (ja) | 2014-07-30 |
| GB2455479A (en) | 2009-06-17 |
| WO2008038018A1 (en) | 2008-04-03 |
| HK1138281A1 (en) | 2010-08-20 |
| GB0906908D0 (en) | 2009-06-03 |
| GB2455479B (en) | 2009-10-28 |
| US20100016311A1 (en) | 2010-01-21 |
| GB2455479C (en) | 2012-05-16 |
| EP2066627A1 (en) | 2009-06-10 |
| ES2443720T3 (es) | 2014-02-20 |
| EP2066627B1 (en) | 2013-10-23 |
| CN101589024A (zh) | 2009-11-25 |
| PL2066627T3 (pl) | 2014-05-30 |
| CN101589024B (zh) | 2014-01-01 |
| US8012967B2 (en) | 2011-09-06 |
| GB0619325D0 (en) | 2006-11-08 |
| CA2664847A1 (en) | 2008-04-03 |
| JP2010505757A (ja) | 2010-02-25 |
| CA2664847C (en) | 2014-12-02 |
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