DK2036538T3 - Farmaceutisk stabil forbindelse bestående af timolol, dorzolamid og brimonidin - Google Patents

Farmaceutisk stabil forbindelse bestående af timolol, dorzolamid og brimonidin

Info

Publication number
DK2036538T3
DK2036538T3 DK08380004.5T DK08380004T DK2036538T3 DK 2036538 T3 DK2036538 T3 DK 2036538T3 DK 08380004 T DK08380004 T DK 08380004T DK 2036538 T3 DK2036538 T3 DK 2036538T3
Authority
DK
Denmark
Prior art keywords
treatment
present
dorzolamide
brimonidine
timolol
Prior art date
Application number
DK08380004.5T
Other languages
English (en)
Inventor
Montano Jose Ruben Tornero
Duran Leopoldo Martin Baiza
Hau Juan De Dios Quintana
Original Assignee
Jimenez Bayardo Arturo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jimenez Bayardo Arturo filed Critical Jimenez Bayardo Arturo
Application granted granted Critical
Publication of DK2036538T3 publication Critical patent/DK2036538T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Botany (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK08380004.5T 2007-09-12 2008-01-10 Farmaceutisk stabil forbindelse bestående af timolol, dorzolamid og brimonidin DK2036538T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2007011165A MX2007011165A (es) 2007-09-12 2007-09-12 Composición farmacéutica estable de timolol, dorzolamida y brimonidina.

Publications (1)

Publication Number Publication Date
DK2036538T3 true DK2036538T3 (da) 2011-10-17

Family

ID=40262890

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08380004.5T DK2036538T3 (da) 2007-09-12 2008-01-10 Farmaceutisk stabil forbindelse bestående af timolol, dorzolamid og brimonidin

Country Status (12)

Country Link
US (1) US20090069345A1 (da)
EP (1) EP2036538B1 (da)
JP (1) JP2009102291A (da)
AT (1) ATE513540T1 (da)
CY (1) CY1111854T1 (da)
DK (1) DK2036538T3 (da)
ES (1) ES2368532T3 (da)
HR (1) HRP20110677T1 (da)
MX (1) MX2007011165A (da)
PL (1) PL2036538T3 (da)
PT (1) PT2036538E (da)
SI (1) SI2036538T1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104324378A (zh) 2009-05-29 2015-02-04 盖尔德马研究及发展公司 用于减少注射引起的皮肤反应的肾上腺素能受体激动剂和填充剂的可注射组合物
RU2012113380A (ru) 2009-09-07 2013-10-20 Микро Лабс Лимитед Офтальмологические композиции, содержащие дорзоламид, тимолол и бримонидин
WO2012026609A1 (ja) * 2010-08-27 2012-03-01 わかもと製薬株式会社 点眼用水性組成物
KR101119610B1 (ko) * 2010-12-02 2012-03-06 한림제약(주) 도르졸라미드, 티몰롤 및 브리모니딘을 포함하는 안과용 액제 조성물
SI2887923T1 (sl) 2012-08-24 2023-09-29 Sun Pharmaceutical Industries Limited Oftalmična formulacija polioksilnega lipida ali polioksilne maščobne kisline in zdravljenje očesnih stanj
JP2017519813A (ja) * 2014-05-23 2017-07-20 オキュラー テクノロジーズ エスアーエールエル 局所製剤およびその使用
TW201726127A (zh) * 2016-01-29 2017-08-01 參天製藥股份有限公司 含有多佐胺、高分子及硼酸之醫藥組成物
RU2747455C2 (ru) 2016-02-29 2021-05-05 Сан Фарма Глобал Фзе Циклоспорин-содержащие лекарственные формы для наружного применения и их применения
US20180318319A1 (en) 2017-05-04 2018-11-08 Ocular Science, Inc. Compositions and Methods for Treating Eyes and Methods of Preparation
US11071724B2 (en) 2019-05-17 2021-07-27 Ocular Science, Inc. Compositions and methods for treating presbyopia
CN116421555A (zh) * 2023-04-27 2023-07-14 亚邦医药股份有限公司 一种酒石酸溴莫尼定滴眼液及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3597239B2 (ja) * 1994-03-31 2004-12-02 ライオン株式会社 安定な点眼剤
US5789435A (en) * 1995-05-22 1998-08-04 Advanced Research And Technology Institute Method to increase retinal and optical nerve head blood flow velocity in order to preserve sight
JP3155689B2 (ja) * 1995-08-10 2001-04-16 昭和薬品化工株式会社 消炎点眼剤
JPH10130156A (ja) * 1996-10-30 1998-05-19 Teika Seiyaku Kk 点眼剤組成物
JP2005526052A (ja) * 2002-02-28 2005-09-02 アイカゲン インコーポレイテッド 眼内圧に関連する疾患を処置するための方法
US7030149B2 (en) * 2002-04-19 2006-04-18 Allergan, Inc. Combination of brimonidine timolol for topical ophthalmic use
US7074827B2 (en) * 2002-10-24 2006-07-11 Sucampo Ag (Usa) Inc. Method for treating ocular hypertension and glaucoma
US20050038103A1 (en) * 2003-08-13 2005-02-17 Amarjit Singh Uses of dorzolamide
EP1848541A4 (en) * 2005-02-07 2013-01-16 Pharmalight Inc METHOD AND DEVICE FOR OPHTHALMIC DELIVERY OF PHARMACEUTICALLY ACTIVE INGREDIENTS
US20070238732A1 (en) * 2006-04-10 2007-10-11 Allergan, Inc. Brimonidine and timolol compositions
AR062046A1 (es) * 2006-07-25 2008-08-10 Osmotica Pharmaceutical Argentina S A Soluciones oftalmicas

Also Published As

Publication number Publication date
US20090069345A1 (en) 2009-03-12
CY1111854T1 (el) 2015-11-04
PT2036538E (pt) 2011-09-27
EP2036538A1 (en) 2009-03-18
JP2009102291A (ja) 2009-05-14
ATE513540T1 (de) 2011-07-15
PL2036538T3 (pl) 2012-01-31
SI2036538T1 (sl) 2011-12-30
ES2368532T3 (es) 2011-11-18
HRP20110677T1 (hr) 2011-12-31
MX2007011165A (es) 2009-03-11
EP2036538B1 (en) 2011-06-22

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