PL2036538T3 - Farmaceutycznie trwała mieszanina składająca się z tymololu, dorzolamidu i brymonidyny - Google Patents

Farmaceutycznie trwała mieszanina składająca się z tymololu, dorzolamidu i brymonidyny

Info

Publication number
PL2036538T3
PL2036538T3 PL08380004T PL08380004T PL2036538T3 PL 2036538 T3 PL2036538 T3 PL 2036538T3 PL 08380004 T PL08380004 T PL 08380004T PL 08380004 T PL08380004 T PL 08380004T PL 2036538 T3 PL2036538 T3 PL 2036538T3
Authority
PL
Poland
Prior art keywords
treatment
present
dorzolamide
brimonidine
timolol
Prior art date
Application number
PL08380004T
Other languages
English (en)
Inventor
Montaño Jose Ruben Tornero
Duran Leopoldo Martin Baiza
Hau Juan De Dios Quintana
Original Assignee
Jimenez Bayardo Arturo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jimenez Bayardo Arturo filed Critical Jimenez Bayardo Arturo
Publication of PL2036538T3 publication Critical patent/PL2036538T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PL08380004T 2007-09-12 2008-01-10 Farmaceutycznie trwała mieszanina składająca się z tymololu, dorzolamidu i brymonidyny PL2036538T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MX2007011165A MX2007011165A (es) 2007-09-12 2007-09-12 Composición farmacéutica estable de timolol, dorzolamida y brimonidina.
EP08380004A EP2036538B1 (en) 2007-09-12 2008-01-10 Pharmaceutically stable compound consisting of timolol, dorzolamide and brimonidine

Publications (1)

Publication Number Publication Date
PL2036538T3 true PL2036538T3 (pl) 2012-01-31

Family

ID=40262890

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08380004T PL2036538T3 (pl) 2007-09-12 2008-01-10 Farmaceutycznie trwała mieszanina składająca się z tymololu, dorzolamidu i brymonidyny

Country Status (12)

Country Link
US (1) US20090069345A1 (pl)
EP (1) EP2036538B1 (pl)
JP (1) JP2009102291A (pl)
AT (1) ATE513540T1 (pl)
CY (1) CY1111854T1 (pl)
DK (1) DK2036538T3 (pl)
ES (1) ES2368532T3 (pl)
HR (1) HRP20110677T1 (pl)
MX (1) MX2007011165A (pl)
PL (1) PL2036538T3 (pl)
PT (1) PT2036538E (pl)
SI (1) SI2036538T1 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2435045A2 (en) 2009-05-29 2012-04-04 Symatese Injectable combination of adrenergic receptor agonists with fillers, for decreasing skin reactions due to injection
RU2012113380A (ru) 2009-09-07 2013-10-20 Микро Лабс Лимитед Офтальмологические композиции, содержащие дорзоламид, тимолол и бримонидин
CN103079595B (zh) * 2010-08-27 2015-11-25 若素制药株式会社 滴眼用水性组合物
KR101119610B1 (ko) * 2010-12-02 2012-03-06 한림제약(주) 도르졸라미드, 티몰롤 및 브리모니딘을 포함하는 안과용 액제 조성물
EP2887923B1 (en) 2012-08-24 2023-04-05 Sun Pharmaceutical Industries Limited Ophthalmic formulation of polyoxyl lipid or polyoxyl fatty acid and treatment of ocular conditions
EP3145549A4 (en) * 2014-05-23 2018-02-14 Ocular Technologies Sàrl Topical formulations and uses thereof
PT3373976T (pt) 2015-11-10 2024-04-02 Sun Pharmaceutical Ind Ltd Formulações tópicas e suas utilizações
TW201726127A (zh) * 2016-01-29 2017-08-01 參天製藥股份有限公司 含有多佐胺、高分子及硼酸之醫藥組成物
WO2017151657A1 (en) 2016-02-29 2017-09-08 Ocular Technologies Sarl Topical cyclosporine-containing formulations and uses thereof
US20180318319A1 (en) 2017-05-04 2018-11-08 Ocular Science, Inc. Compositions and Methods for Treating Eyes and Methods of Preparation
US11071724B2 (en) 2019-05-17 2021-07-27 Ocular Science, Inc. Compositions and methods for treating presbyopia
CN116421555A (zh) * 2023-04-27 2023-07-14 亚邦医药股份有限公司 一种酒石酸溴莫尼定滴眼液及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3597239B2 (ja) * 1994-03-31 2004-12-02 ライオン株式会社 安定な点眼剤
US5789435A (en) * 1995-05-22 1998-08-04 Advanced Research And Technology Institute Method to increase retinal and optical nerve head blood flow velocity in order to preserve sight
JP3155689B2 (ja) * 1995-08-10 2001-04-16 昭和薬品化工株式会社 消炎点眼剤
JPH10130156A (ja) * 1996-10-30 1998-05-19 Teika Seiyaku Kk 点眼剤組成物
EP1487430A4 (en) * 2002-02-28 2007-08-22 Icagen Inc METHOD FOR THE TREATMENT OF DISEASES RELATED TO THE EYE REMINDER
US7030149B2 (en) * 2002-04-19 2006-04-18 Allergan, Inc. Combination of brimonidine timolol for topical ophthalmic use
US7074827B2 (en) * 2002-10-24 2006-07-11 Sucampo Ag (Usa) Inc. Method for treating ocular hypertension and glaucoma
US20050038103A1 (en) * 2003-08-13 2005-02-17 Amarjit Singh Uses of dorzolamide
WO2006082588A2 (en) * 2005-02-07 2006-08-10 Pharmalight Inc. Method and device for ophthalmic administration of active pharmaceutical ingredients
US20070238732A1 (en) * 2006-04-10 2007-10-11 Allergan, Inc. Brimonidine and timolol compositions
US20080050335A1 (en) * 2006-07-25 2008-02-28 Osmotica Corp. Ophthalmic Solutions

Also Published As

Publication number Publication date
US20090069345A1 (en) 2009-03-12
DK2036538T3 (da) 2011-10-17
ES2368532T3 (es) 2011-11-18
JP2009102291A (ja) 2009-05-14
EP2036538A1 (en) 2009-03-18
ATE513540T1 (de) 2011-07-15
MX2007011165A (es) 2009-03-11
CY1111854T1 (el) 2015-11-04
SI2036538T1 (sl) 2011-12-30
HRP20110677T1 (hr) 2011-12-31
EP2036538B1 (en) 2011-06-22
PT2036538E (pt) 2011-09-27

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