DK201885A - Monoklonalt antistof, dets fremstilling og anvendelse - Google Patents

Monoklonalt antistof, dets fremstilling og anvendelse Download PDF

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Publication number
DK201885A
DK201885A DK201885A DK201885A DK201885A DK 201885 A DK201885 A DK 201885A DK 201885 A DK201885 A DK 201885A DK 201885 A DK201885 A DK 201885A DK 201885 A DK201885 A DK 201885A
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DK
Denmark
Prior art keywords
molecular
reducing conditions
manufacturing
antigens
monoclonal antibody
Prior art date
Application number
DK201885A
Other languages
English (en)
Other versions
DK169507B1 (da
DK201885D0 (da
Inventor
Klaus Bosslet
Hans-Harald Sedlacek
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of DK201885D0 publication Critical patent/DK201885D0/da
Publication of DK201885A publication Critical patent/DK201885A/da
Application granted granted Critical
Publication of DK169507B1 publication Critical patent/DK169507B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007—Carcino-embryonic Antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK201885A 1984-05-07 1985-05-06 Monoklonale antistoffer, epitop, der genkendes deraf, fremgangsmåde til fremstilling af antistofferne samt deres anvendelse i et in vitro-diagnostikum, som bærere for et farmaceutisk virksomt stof og til fremstilling af et terapeutikum DK169507B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843416774 DE3416774A1 (de) 1984-05-07 1984-05-07 Monoklonale antikoerper, verfahren zu ihrer herstellung sowie ihre verwendung
DE3416774 1984-05-07

Publications (3)

Publication Number Publication Date
DK201885D0 DK201885D0 (da) 1985-05-06
DK201885A true DK201885A (da) 1985-11-08
DK169507B1 DK169507B1 (da) 1994-11-14

Family

ID=6235105

Family Applications (1)

Application Number Title Priority Date Filing Date
DK201885A DK169507B1 (da) 1984-05-07 1985-05-06 Monoklonale antistoffer, epitop, der genkendes deraf, fremgangsmåde til fremstilling af antistofferne samt deres anvendelse i et in vitro-diagnostikum, som bærere for et farmaceutisk virksomt stof og til fremstilling af et terapeutikum

Country Status (7)

Country Link
EP (2) EP0516190B1 (da)
JP (1) JPH07108918B2 (da)
AT (2) ATE89605T1 (da)
AU (1) AU594305B2 (da)
CA (1) CA1277613C (da)
DE (3) DE3416774A1 (da)
DK (1) DK169507B1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0131627B1 (en) * 1983-01-21 1992-05-20 PRIMUS, Frederick James Specific cea-family antigens, antibodies specific thereto and their methods of use
DE3531301A1 (de) * 1985-09-02 1987-03-05 Behringwerke Ag Monoklonale antikoerper gegen tumorassoziierte glykoproteine, verfahren zu ihrer herstellung sowie ihre verwendung
DE3629640A1 (de) * 1986-08-30 1988-03-03 Behringwerke Ag Verwendung monoklonaler antikoerper zur therapie von tumoren
DE3432714A1 (de) * 1984-09-06 1986-04-24 Behringwerke Ag, 3550 Marburg Tumortherapeutikum und verfahren zu seiner herstellung
EP0180413B1 (en) * 1984-10-26 1991-10-02 Wakunaga Seiyaku Kabushiki Kaisha Anti-human cancer monoclonal antibody
AU601379B2 (en) * 1985-11-07 1990-09-13 Trustees Of Columbia University In The City Of New York, The Antigen indicative of human breast cancer and assays based thereon
DE3909799A1 (de) 1989-03-24 1990-09-27 Behringwerke Ag Monoklonale antikoerper (mak) gegen tumorassoziierte antigene, ihre herstellung und verwendung
HUE038225T2 (hu) 2011-08-23 2018-10-29 Roche Glycart Ag Bispecifikus, T-sejtaktiváló antigénkötõ, molekulák
RU2015140917A (ru) 2013-02-26 2017-04-03 Роше Гликарт Аг Биспецифические антигенсвязывающие молекулы, активирующие т-клетки
EP3444278A1 (en) 2013-02-26 2019-02-20 Roche Glycart AG Bispecific t cell activating antigen binding molecules

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4349528A (en) * 1979-11-21 1982-09-14 The Wistar Institute Monocolonal hybridoma antibody specific for high molecular weight carcinoembryonic antigen
JPH0811075B2 (ja) * 1982-06-30 1996-02-07 雄治 松岡 単クローン性抗ｃｅａ抗体
EP0131627B1 (en) * 1983-01-21 1992-05-20 PRIMUS, Frederick James Specific cea-family antigens, antibodies specific thereto and their methods of use
DE3329184A1 (de) * 1983-08-12 1985-02-21 Behringwerke Ag, 3550 Marburg Monoklonale antikoerper mit spezifitaet fuer membran-assoziierte antigene
US4753894A (en) * 1984-02-08 1988-06-28 Cetus Corporation Monoclonal anti-human breast cancer antibodies
EP0160446B1 (en) * 1984-05-01 1992-06-17 Ciba Corning Diagnostics Corp. Breast tumor-associated antigen and monoclonal antibodies specific thereto

Also Published As

Publication number Publication date
JPS60252499A (ja) 1985-12-13
EP0516190A3 (en) 1992-12-16
DE3416774A1 (de) 1985-11-14
EP0160897A2 (de) 1985-11-13
CA1277613C (en) 1990-12-11
EP0160897B1 (de) 1993-05-19
DE3588240D1 (de) 2002-08-29
AU594305B2 (en) 1990-03-08
AU4201385A (en) 1985-11-14
EP0516190B1 (de) 2002-07-24
EP0516190A2 (de) 1992-12-02
DE3587346D1 (de) 1993-06-24
ATE89605T1 (de) 1993-06-15
DK169507B1 (da) 1994-11-14
ATE221122T1 (de) 2002-08-15
JPH07108918B2 (ja) 1995-11-22
DK201885D0 (da) 1985-05-06
EP0160897A3 (en) 1987-09-23

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed