DK1998805T3 - Tumorterapi med et antistof til vaskulær endotelial vækstfaktor og et antistof til human epitelial vækstfaktor receptor type 2 - Google Patents
Tumorterapi med et antistof til vaskulær endotelial vækstfaktor og et antistof til human epitelial vækstfaktor receptor type 2Info
- Publication number
- DK1998805T3 DK1998805T3 DK07711981.6T DK07711981T DK1998805T3 DK 1998805 T3 DK1998805 T3 DK 1998805T3 DK 07711981 T DK07711981 T DK 07711981T DK 1998805 T3 DK1998805 T3 DK 1998805T3
- Authority
- DK
- Denmark
- Prior art keywords
- antibody
- growth factor
- epitelial
- human
- receptor type
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3015—Breast
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06111523 | 2006-03-22 | ||
| EP06021815 | 2006-10-18 | ||
| PCT/EP2007/002448 WO2007107329A1 (en) | 2006-03-22 | 2007-03-20 | Tumor therapy with an antibody for vascular endothelial groeth factor and an antibody for human epithelial growth factor receptor type 2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1998805T3 true DK1998805T3 (da) | 2012-10-08 |
Family
ID=37998279
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11164996.8T DK2364732T3 (da) | 2006-03-22 | 2007-03-20 | Tumorterapi med et antistof til vaskulær endotelvækstfaktor og et antistof til human epitelvækstfaktorreceptor type 2 |
| DK07711981.6T DK1998805T3 (da) | 2006-03-22 | 2007-03-20 | Tumorterapi med et antistof til vaskulær endotelial vækstfaktor og et antistof til human epitelial vækstfaktor receptor type 2 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11164996.8T DK2364732T3 (da) | 2006-03-22 | 2007-03-20 | Tumorterapi med et antistof til vaskulær endotelvækstfaktor og et antistof til human epitelvækstfaktorreceptor type 2 |
Country Status (25)
| Country | Link |
|---|---|
| US (4) | US20070224203A1 (da) |
| EP (2) | EP1998805B1 (da) |
| JP (2) | JP5795463B2 (da) |
| KR (1) | KR101089070B1 (da) |
| AR (1) | AR059982A1 (da) |
| BR (1) | BRPI0709025A2 (da) |
| CA (1) | CA2645891A1 (da) |
| CR (1) | CR10244A (da) |
| DK (2) | DK2364732T3 (da) |
| EC (1) | ECSP088753A (da) |
| ES (2) | ES2595238T3 (da) |
| HK (1) | HK1131037A1 (da) |
| HU (1) | HUE029615T2 (da) |
| IL (1) | IL193675A0 (da) |
| MA (1) | MA30290B1 (da) |
| MX (1) | MX2008012014A (da) |
| MY (1) | MY151449A (da) |
| NO (1) | NO20083761L (da) |
| NZ (1) | NZ570921A (da) |
| PL (2) | PL1998805T3 (da) |
| RU (1) | RU2538664C2 (da) |
| SG (1) | SG170730A1 (da) |
| SI (2) | SI2364732T1 (da) |
| TW (1) | TW200812615A (da) |
| WO (1) | WO2007107329A1 (da) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA9811162B (en) | 1997-12-12 | 2000-06-07 | Genentech Inc | Treatment with anti-ERBB2 antibodies. |
| US20020064785A1 (en) * | 2000-05-19 | 2002-05-30 | Genentech Inc. | Gene detection assay for improving the likelihood of an effective response to an ErbB antagonist cancer therapy |
| NZ621449A (en) | 2003-05-30 | 2015-07-31 | Genentech Inc | Treatment with anti-vegf antibodies |
| KR20170054551A (ko) * | 2004-07-22 | 2017-05-17 | 제넨테크, 인크. | Ｈｅｒ２ 항체 조성물 |
| JO3000B1 (ar) | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| WO2006063042A2 (en) * | 2004-12-07 | 2006-06-15 | Genentech, Inc. | Selecting patients for therapy with a her inhibitor |
| UA94899C2 (ru) | 2005-01-21 | 2011-06-25 | Дженентек, Инк. | Фиксированное дозирование антител к her |
| RS53128B (en) | 2005-02-23 | 2014-06-30 | Genentech Inc. | Extending the time of disease progression or survival in patients with ovarian cancers using PERTUZUMAB |
| PE20070207A1 (es) * | 2005-07-22 | 2007-03-09 | Genentech Inc | Tratamiento combinado de los tumores que expresan el her |
| TW200812615A (en) * | 2006-03-22 | 2008-03-16 | Hoffmann La Roche | Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2 |
| SG174090A1 (en) * | 2006-08-21 | 2011-09-29 | Hoffmann La Roche | Tumor therapy with an anti-vegf antibody |
| SI2132573T1 (sl) | 2007-03-02 | 2014-07-31 | Genentech, Inc. | Napovedovanje odziva na inhibitor dimerizacije HER na osnovi nizke ekspresije HER3 |
| TWI472339B (zh) | 2008-01-30 | 2015-02-11 | Genentech Inc | 包含結合至ｈｅｒ２結構域ii之抗體及其酸性變異體的組合物 |
| BRPI0812682A2 (pt) | 2008-06-16 | 2010-06-22 | Genentech Inc | tratamento de cáncer de mama metastático |
| US8268314B2 (en) | 2008-10-08 | 2012-09-18 | Hoffmann-La Roche Inc. | Bispecific anti-VEGF/anti-ANG-2 antibodies |
| KR101397088B1 (ko) | 2011-06-10 | 2014-05-19 | 강원대학교산학협력단 | 암세포 증식 억제와 혈관신생 억제를 위한 융합 단백질 및 이를 포함한 항암 조성물 |
| WO2012169822A2 (ko) * | 2011-06-10 | 2012-12-13 | 강원대학교산학협력단 | 암세포 증식 억제와 혈관신생 억제를 위한 융합 단백질 및 이를 포함한 항암 조성물 |
| CN104334189A (zh) | 2011-10-14 | 2015-02-04 | 霍夫曼-拉罗奇有限公司 | Her2二聚化抑制剂帕妥珠单抗的用途和包含her2二聚化抑制剂帕妥珠单抗的制品 |
| MY183712A (en) | 2012-07-13 | 2021-03-09 | Roche Glycart Ag | Bispecific anti-vegf/anti-ang-2 antibodies and their use in the treatment of ocular vascular diseases |
| JP6511609B2 (ja) | 2013-03-13 | 2019-05-22 | ジェネンテック， インコーポレイテッド | 抗体製剤 |
| PE20151769A1 (es) | 2013-04-16 | 2015-12-11 | Genentech Inc | Variantes de pertuzumab y su evalaucion |
| MX2016014007A (es) | 2014-04-25 | 2017-01-11 | Genentech Inc | Metodos para el tratamiento de cancer de mama temprano con trastuzumab-emtansina(mcc-dm1) y pertuzumab. |
| AU2015318001B2 (en) | 2014-09-15 | 2021-03-25 | Genentech, Inc. | Antibody formulations |
| LT3302551T (lt) | 2015-05-30 | 2024-09-10 | F. Hoffmann-La Roche Ag | Anksčiau negydyto metastazavusio her2 teigiamo krūties vėžio gydymo būdai |
| WO2017087280A1 (en) | 2015-11-16 | 2017-05-26 | Genentech, Inc. | Methods of treating her2-positive cancer |
| CN106729743B (zh) | 2015-11-23 | 2021-09-21 | 四川科伦博泰生物医药股份有限公司 | 抗ErbB2抗体-药物偶联物及其组合物、制备方法和应用 |
| WO2018125589A1 (en) | 2016-12-28 | 2018-07-05 | Genentech, Inc. | Treatment of advanced her2 expressing cancer |
| SG10202011384XA (en) | 2017-01-17 | 2021-01-28 | Genentech Inc | Subcutaneous her2 antibody formulations |
| EP3589661B1 (en) | 2017-03-02 | 2023-11-01 | Genentech, Inc. | Adjuvant treatment of her2-positive breast cancer |
| JP2020517273A (ja) | 2017-04-24 | 2020-06-18 | ジェネンテック， インコーポレイテッド | 膜貫通ドメインまたは膜近傍ドメインにおけるＥｒｂＢ２／Ｈｅｒ２突然変異 |
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| JP3040121B2 (ja) | 1988-01-12 | 2000-05-08 | ジェネンテク，インコーポレイテッド | 増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法 |
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| BR9709974A (pt) | 1996-06-27 | 1999-08-10 | Pfizer | Derivados de 2-(2-oxo-etidileno)-imidazolidin-4-ona e seu uso como inibidores da transferase da proteina de farnesila |
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| US20020032315A1 (en) | 1997-08-06 | 2002-03-14 | Manuel Baca | Anti-vegf antibodies |
| ZA9811162B (en) | 1997-12-12 | 2000-06-07 | Genentech Inc | Treatment with anti-ERBB2 antibodies. |
| JPH11236333A (ja) | 1997-12-30 | 1999-08-31 | Pfizer Prod Inc | 抗ガン剤として有用なイミダゾリン−４−オン誘導体 |
| IL139707A0 (en) | 1998-05-15 | 2002-02-10 | Imclone Systems Inc | Treatment of human tumors with radiation and inhibitors of growth factor receptor tyrosine kinases |
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| BR9913315A (pt) | 1998-08-27 | 2001-05-22 | Pfizer Prod Inc | Derivados de quinolin-2-ona úteis como agentes anticâncer |
| DK1135498T3 (da) | 1998-11-18 | 2008-05-26 | Genentech Inc | Antistofvarianter med höjere bindingsaffinitet end forældreantistoffer |
| EP1006113A1 (en) | 1998-12-02 | 2000-06-07 | Pfizer Products Inc. | Derivatives of 2-(2-oxo-ethylidene)-imidazolidin-4-one and their use to inhibit abnormal cell growth |
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| TR200201296T2 (tr) | 1999-02-11 | 2002-07-22 | Pfizer Products Inc. | Antikanser maddeleri olarak faydalı heteroaril-ikame edilmiş kinolin-2-on türevleri |
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| UA75055C2 (uk) | 1999-11-30 | 2006-03-15 | Пфайзер Продактс Інк. | Похідні бензоімідазолу, що використовуються як антипроліферативний засіб, фармацевтична композиція на їх основі |
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| WO2003087131A2 (en) | 2002-04-10 | 2003-10-23 | Genentech, Inc | Anti-her2 antibody variants |
| NZ621449A (en) | 2003-05-30 | 2015-07-31 | Genentech Inc | Treatment with anti-vegf antibodies |
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| TW200812615A (en) * | 2006-03-22 | 2008-03-16 | Hoffmann La Roche | Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2 |
-
2007
- 2007-03-19 TW TW096109369A patent/TW200812615A/zh unknown
- 2007-03-20 WO PCT/EP2007/002448 patent/WO2007107329A1/en active Application Filing
- 2007-03-20 KR KR1020087023137A patent/KR101089070B1/ko active IP Right Grant
- 2007-03-20 ES ES11164996.8T patent/ES2595238T3/es active Active
- 2007-03-20 US US11/725,777 patent/US20070224203A1/en not_active Abandoned
- 2007-03-20 JP JP2009500761A patent/JP5795463B2/ja not_active Expired - Fee Related
- 2007-03-20 PL PL07711981T patent/PL1998805T3/pl unknown
- 2007-03-20 CA CA002645891A patent/CA2645891A1/en not_active Abandoned
- 2007-03-20 DK DK11164996.8T patent/DK2364732T3/da active
- 2007-03-20 AR ARP070101125A patent/AR059982A1/es unknown
- 2007-03-20 SI SI200731837A patent/SI2364732T1/sl unknown
- 2007-03-20 HU HUE11164996A patent/HUE029615T2/en unknown
- 2007-03-20 MY MYPI20083705 patent/MY151449A/en unknown
- 2007-03-20 ES ES07711981T patent/ES2392873T3/es active Active
- 2007-03-20 NZ NZ570921A patent/NZ570921A/en not_active IP Right Cessation
- 2007-03-20 EP EP07711981A patent/EP1998805B1/en not_active Revoked
- 2007-03-20 SG SG201101893-4A patent/SG170730A1/en unknown
- 2007-03-20 EP EP11164996.8A patent/EP2364732B1/en not_active Revoked
- 2007-03-20 MX MX2008012014A patent/MX2008012014A/es active IP Right Grant
- 2007-03-20 RU RU2008141433/15A patent/RU2538664C2/ru not_active IP Right Cessation
- 2007-03-20 BR BRPI0709025-0A patent/BRPI0709025A2/pt not_active Application Discontinuation
- 2007-03-20 PL PL11164996T patent/PL2364732T3/pl unknown
- 2007-03-20 DK DK07711981.6T patent/DK1998805T3/da active
- 2007-03-20 SI SI200731062T patent/SI1998805T1/sl unknown
-
2008
- 2008-08-25 IL IL193675A patent/IL193675A0/en not_active IP Right Cessation
- 2008-08-26 CR CR10244A patent/CR10244A/es not_active Application Discontinuation
- 2008-09-01 NO NO20083761A patent/NO20083761L/no not_active Application Discontinuation
- 2008-09-19 EC EC2008008753A patent/ECSP088753A/es unknown
- 2008-09-22 MA MA31255A patent/MA30290B1/fr unknown
-
2009
- 2009-09-30 HK HK09109049.3A patent/HK1131037A1/xx not_active IP Right Cessation
-
2010
- 2010-11-16 US US12/947,264 patent/US9090700B2/en not_active Expired - Fee Related
-
2012
- 2012-07-13 JP JP2012157442A patent/JP2012207036A/ja active Pending
-
2015
- 2015-06-19 US US14/745,026 patent/US20150283238A1/en not_active Abandoned
-
2017
- 2017-05-10 US US15/591,922 patent/US20170239353A1/en not_active Abandoned
Also Published As
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