DK192583A - Phenylalaninderivater og deres anvendelse til fremme af laegemiddelabsorption - Google Patents

Phenylalaninderivater og deres anvendelse til fremme af laegemiddelabsorption Download PDF

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Publication number
DK192583A
DK192583A DK192583A DK192583A DK192583A DK 192583 A DK192583 A DK 192583A DK 192583 A DK192583 A DK 192583A DK 192583 A DK192583 A DK 192583A DK 192583 A DK192583 A DK 192583A
Authority
DK
Denmark
Prior art keywords
promotion
phenylalanine derivatives
pharmaceutical laboratory
laboratory
pharmaceutical
Prior art date
Application number
DK192583A
Other languages
English (en)
Other versions
DK192583D0 (da
DK170855B1 (da
Inventor
Shigeshi Toyoshima
Yoshiko Seto
Koji Fukushima
Izumi Kumashiro
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP57073306A external-priority patent/JPS58189121A/ja
Priority claimed from JP6599983A external-priority patent/JPS59190926A/ja
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of DK192583D0 publication Critical patent/DK192583D0/da
Publication of DK192583A publication Critical patent/DK192583A/da
Application granted granted Critical
Publication of DK170855B1 publication Critical patent/DK170855B1/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK192583A 1982-04-30 1983-04-28 Phenylalaninderivater DK170855B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP7330682 1982-04-30
JP57073306A JPS58189121A (ja) 1982-04-30 1982-04-30 インシユリン投与賦活剤
JP6599983 1983-04-14
JP6599983A JPS59190926A (ja) 1983-04-14 1983-04-14 吸収性付与剤

Publications (3)

Publication Number Publication Date
DK192583D0 DK192583D0 (da) 1983-04-28
DK192583A true DK192583A (da) 1983-10-31
DK170855B1 DK170855B1 (da) 1996-02-12

Family

ID=26407159

Family Applications (1)

Application Number Title Priority Date Filing Date
DK192583A DK170855B1 (da) 1982-04-30 1983-04-28 Phenylalaninderivater

Country Status (5)

Country Link
US (1) US4670584A (da)
EP (1) EP0093551B1 (da)
CA (1) CA1250090A (da)
DE (1) DE3382112D1 (da)
DK (1) DK170855B1 (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5053389A (en) * 1986-04-18 1991-10-01 Per Balschmidt Insulin preparation for non-parenteral administration

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6354321A (ja) * 1985-03-27 1988-03-08 Ajinomoto Co Inc 血糖降下剤
DE3674474D1 (de) * 1985-06-08 1990-10-31 Suntory Ltd Phenoxyacetylamidderivate, verfahren zu ihrer herstellung und ihre verwendung.
JPH0791251B2 (ja) * 1987-11-20 1995-10-04 味の素株式会社 フェニルアラニン誘導体及びその用途
US5463116A (en) * 1991-07-30 1995-10-31 Ajinomoto Co., Inc. Crystals of N- (trans-4-isopropylcyclohexlycarbonyl)-D-phenylalanine and methods for preparing them
US7056935B2 (en) 1995-06-07 2006-06-06 Gpi Nil Holdings, Inc. Rotamase enzyme activity inhibitors
US20020042377A1 (en) * 1995-06-07 2002-04-11 Steiner Joseph P. Rotamase enzyme activity inhibitors
CN1261449C (zh) * 1999-04-26 2006-06-28 味之素株式会社 促黑素细胞激素抑制剂
US6878749B2 (en) * 1999-09-17 2005-04-12 Novartis Ag Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
EP1265638A1 (en) * 1999-11-12 2002-12-18 Pharmaderm Laboratories Ltd. Compositions for transdermal and transmucosal administration of therapeutic agents
DK1334962T3 (da) 2000-10-18 2007-12-10 Ajinomoto Kk Fremgangsmåder til fremstilling af acylphenylalanin
FR2828102B1 (fr) * 2001-03-28 2004-07-09 Ifc Sa Utilisation des lipoaminoacides dans une composition pharmaceutique comme promoteur et systeme disperse a usage pharmaceutique contenant de tels composes
GB2389582A (en) * 2002-06-13 2003-12-17 Bayer Ag Pharmaceutically active carboxamides
EP2919804B1 (fr) 2012-11-13 2018-01-31 Adocia Formulation à action rapide d'insuline comprenant un composé anionique substitué
US9795678B2 (en) * 2014-05-14 2017-10-24 Adocia Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound
FR3020947B1 (fr) * 2014-05-14 2018-08-31 Adocia Composition aqueuse comprenant au moins une proteine et un agent solubilisant, sa preparation et ses utilisations
FR3043557B1 (fr) * 2015-11-16 2019-05-31 Adocia Composition a action rapide d'insuline comprenant un citrate substitue
WO2017084696A1 (fr) * 2015-11-16 2017-05-26 Adocia Composition a action rapide d'insuline comprenant un compose anionique substitue et un compose polyanionique

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5123056B2 (da) * 1972-04-03 1976-07-14
IL46207A0 (en) * 1974-12-09 1975-03-13 Technion Res & Dev Foundation Process for the direct manufacture of acyl derivatives of aromatic alpha-amino acids
DE3003898A1 (de) * 1980-02-02 1981-08-13 Dynamit Nobel Ag, 5210 Troisdorf Verfahren zur acylierung von aminocarbonsaeuren
FR2509175B1 (fr) * 1981-03-06 1987-01-16 Toyo Jozo Kk Preparation therapeutique ayant d'excellentes proprietes d'absorption

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5053389A (en) * 1986-04-18 1991-10-01 Per Balschmidt Insulin preparation for non-parenteral administration

Also Published As

Publication number Publication date
DK192583D0 (da) 1983-04-28
US4670584A (en) 1987-06-02
CA1250090A (en) 1989-02-14
DK170855B1 (da) 1996-02-12
EP0093551A3 (en) 1985-11-21
EP0093551B1 (en) 1991-01-16
DE3382112D1 (de) 1991-02-21
EP0093551A2 (en) 1983-11-09

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed