DK191D0 - Ledersekvens, der frembringer en post-translational modifikation af polypeptider i bakterier, samt gen derfor - Google Patents
Ledersekvens, der frembringer en post-translational modifikation af polypeptider i bakterier, samt gen derforInfo
- Publication number
- DK191D0 DK191D0 DK000191A DK191A DK191D0 DK 191 D0 DK191 D0 DK 191D0 DK 000191 A DK000191 A DK 000191A DK 191 A DK191 A DK 191A DK 191 D0 DK191 D0 DK 191D0
- Authority
- DK
- Denmark
- Prior art keywords
- polypeptides
- post
- leader sequence
- bacteries
- translational modification
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/90—Fusion polypeptide containing a motif for post-translational modification
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/214,959 US5218101A (en) | 1988-07-05 | 1988-07-05 | Leader sequence inducing a post-translational modification of polypeptides in bacteria, and gene therefor |
PCT/US1989/002820 WO1990000558A1 (en) | 1988-07-05 | 1989-06-30 | Leader sequence inducing a post-translational modification of polypeptides in bacteria, and gene therefor |
Publications (2)
Publication Number | Publication Date |
---|---|
DK191A DK191A (da) | 1991-01-02 |
DK191D0 true DK191D0 (da) | 1991-01-02 |
Family
ID=22801074
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK000191A DK191D0 (da) | 1988-07-05 | 1991-01-02 | Ledersekvens, der frembringer en post-translational modifikation af polypeptider i bakterier, samt gen derfor |
Country Status (14)
Country | Link |
---|---|
US (1) | US5218101A (de) |
EP (1) | EP0423224B1 (de) |
JP (2) | JP3326172B2 (de) |
KR (1) | KR0137961B1 (de) |
AT (1) | ATE175417T1 (de) |
AU (1) | AU640110B2 (de) |
CA (1) | CA1339414C (de) |
DE (2) | DE68928899D1 (de) |
DK (1) | DK191D0 (de) |
IL (1) | IL90832A (de) |
NO (1) | NO309200B1 (de) |
NZ (1) | NZ229538A (de) |
WO (1) | WO1990000558A1 (de) |
ZA (1) | ZA894721B (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5516682A (en) * | 1988-07-05 | 1996-05-14 | University Of Maryland | Subtilin variant of enhanced stability and activity |
US5348881A (en) * | 1990-03-13 | 1994-09-20 | Quest International Flavors & Good Ingredients Company, Division Of Indopco, Inc. | Multiple bacteriocin producing lactococcus and compositions |
NL9000753A (nl) * | 1990-03-30 | 1991-10-16 | Nl Zuivelonderzoek Inst | Dna-fragment, ten minste coderend voor een deel van het extracellulaire eiwit met een schijnbaar molecuulgewicht van 60 kda van lactococcus lactis stammen zoals de lactococcus lactis ssp. lactis stam mg1363, combinaties hiervan met voor homologe of heterologe eiwitten coderende dna-sequenties alsmede de hiermee verkregen homologe en heterologe eiwitten. |
WO1992018633A1 (en) * | 1991-04-11 | 1992-10-29 | Stichting Nederlands Instituut Voor Zuivelonderzoek (Nizo) | Lantibiotics similar to nisin a, lactic acid bacteria which produce such lantibiotics, method for constructing such lactic acid bacteria and method for preserving foodstuffs with the aid of these lantibiotics and these lactic acid bacteria producing lantibiotics |
US5861376A (en) * | 1991-07-01 | 1999-01-19 | Quest International Flavors & Food Ingredients Company, Division Of Indopco, Inc. | Synthetically derived peptide |
GB9207267D0 (en) * | 1992-04-02 | 1992-05-13 | Agricultural & Food Res | Nisins |
ATE255165T1 (de) * | 1994-09-12 | 2003-12-15 | Aventis Pharma Gmbh | Rekombinantes mersacidin und verfahren zu seiner herstellung |
US5919695A (en) * | 1997-04-22 | 1999-07-06 | Quest International, B.V. | Method and culture for inhibiting undesired microorganisms with culture of Bacillus subtilis |
WO1999003352A1 (en) * | 1997-07-18 | 1999-01-28 | University Of Maryland | Sublancin lantibiotic produced by bacillus subtilis 168 |
US6953683B2 (en) * | 1997-07-18 | 2005-10-11 | University Of Maryland | Compositions and methods of inhibiting bacterial spore germination |
WO2000039152A1 (en) * | 1998-12-24 | 2000-07-06 | University Of Maryland | Stable subtilin and methods of manufacture |
US7033766B2 (en) * | 2000-06-29 | 2006-04-25 | University Of Maryland Office Of Technology Commercialization | Construction and screening of lantibody display libraries |
US6846804B2 (en) * | 2000-06-29 | 2005-01-25 | University Of Maryland, College Park Office Of Technology Commercialization | Construction of a structural variant of sublancin to facilitate its isolation and use in bioremediation of environmental contamination by gram-positive spore formers such as bacillus anthrasis |
US6759205B2 (en) | 2000-06-29 | 2004-07-06 | University Of Maryland | Construction of a strain of Bacillus subtilis 168 that displays the sublancin lantibiotic on the surface of the cell |
WO2003063887A1 (en) * | 2002-01-14 | 2003-08-07 | University Of Maryland, College Park | Compositions and method of inhibiting bacterial spore germination |
US6861236B2 (en) * | 2002-05-24 | 2005-03-01 | Applied Nanosystems B.V. | Export and modification of (poly)peptides in the lantibiotic way |
CN101115838B (zh) * | 2004-12-07 | 2015-08-12 | 莫菲西斯公司 | 产生和分泌修饰的肽的方法 |
WO2007093548A1 (en) * | 2006-02-13 | 2007-08-23 | Boehringer Ingelheim Vetmedica Gmbh | Method for the manufacture of lantibiotics |
US7993873B2 (en) * | 2006-06-29 | 2011-08-09 | The Invention Science Fund I, Llc | Apparatus for arbitrary peptide synthesis |
US7910695B2 (en) * | 2006-06-29 | 2011-03-22 | The Invention Science Fund I, Llc | Methods for arbitrary peptide synthesis |
US7923533B2 (en) * | 2006-06-29 | 2011-04-12 | The Invention Science Fund I, Llc | Methods for arbitrary peptide synthesis |
US7879975B2 (en) * | 2006-06-29 | 2011-02-01 | The Invention Science Fund I, Llc | Methods for arbitrary peptide synthesis |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4716115A (en) * | 1983-09-06 | 1987-12-29 | Microlife Technics, Inc. | Derived nisin producing microorganisms, method of production and use and products obtained thereby |
-
1988
- 1988-07-05 US US07/214,959 patent/US5218101A/en not_active Expired - Fee Related
-
1989
- 1989-06-14 NZ NZ229538A patent/NZ229538A/en unknown
- 1989-06-21 ZA ZA894721A patent/ZA894721B/xx unknown
- 1989-06-30 DE DE68928899A patent/DE68928899D1/de not_active Expired - Fee Related
- 1989-06-30 WO PCT/US1989/002820 patent/WO1990000558A1/en active IP Right Grant
- 1989-06-30 AU AU39684/89A patent/AU640110B2/en not_active Ceased
- 1989-06-30 KR KR1019900700460A patent/KR0137961B1/ko not_active IP Right Cessation
- 1989-06-30 AT AT89908558T patent/ATE175417T1/de not_active IP Right Cessation
- 1989-06-30 DE DE68928899T patent/DE68928899T4/de not_active Expired - Lifetime
- 1989-06-30 JP JP50801189A patent/JP3326172B2/ja not_active Expired - Fee Related
- 1989-06-30 EP EP89908558A patent/EP0423224B1/de not_active Expired - Lifetime
- 1989-06-30 IL IL9083289A patent/IL90832A/en not_active IP Right Cessation
- 1989-07-04 CA CA000604753A patent/CA1339414C/en not_active Expired - Fee Related
-
1990
- 1990-12-28 NO NO905638A patent/NO309200B1/no not_active IP Right Cessation
-
1991
- 1991-01-02 DK DK000191A patent/DK191D0/da not_active Application Discontinuation
-
2001
- 2001-11-08 JP JP2001343857A patent/JP3418388B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH03505670A (ja) | 1991-12-12 |
NO309200B1 (no) | 2000-12-27 |
CA1339414C (en) | 1997-09-02 |
KR0137961B1 (ko) | 1998-04-30 |
AU3968489A (en) | 1990-02-05 |
DK191A (da) | 1991-01-02 |
EP0423224B1 (de) | 1999-01-07 |
ATE175417T1 (de) | 1999-01-15 |
JP2002191383A (ja) | 2002-07-09 |
EP0423224A1 (de) | 1991-04-24 |
NZ229538A (en) | 1992-01-29 |
US5218101A (en) | 1993-06-08 |
JP3326172B2 (ja) | 2002-09-17 |
EP0423224A4 (en) | 1991-11-06 |
AU640110B2 (en) | 1993-08-19 |
NO905638L (no) | 1990-12-28 |
WO1990000558A1 (en) | 1990-01-25 |
KR900701819A (ko) | 1990-12-04 |
DE68928899T2 (de) | 1999-08-12 |
DE68928899T4 (de) | 1999-11-25 |
IL90832A (en) | 1995-06-29 |
IL90832A0 (en) | 1990-01-18 |
NO905638D0 (no) | 1990-12-28 |
ZA894721B (en) | 1990-03-28 |
DE68928899D1 (de) | 1999-02-18 |
JP3418388B2 (ja) | 2003-06-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |