DK189888D0 - Stabile oploesningsmiddeladdukter - Google Patents
Stabile oploesningsmiddeladdukterInfo
- Publication number
- DK189888D0 DK189888D0 DK189888A DK189888A DK189888D0 DK 189888 D0 DK189888 D0 DK 189888D0 DK 189888 A DK189888 A DK 189888A DK 189888 A DK189888 A DK 189888A DK 189888 D0 DK189888 D0 DK 189888D0
- Authority
- DK
- Denmark
- Prior art keywords
- addresses
- stable solvent
- solvent
- stable
- solvent addresses
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP87105803 | 1987-04-19 | ||
| EP87105803A EP0287690B1 (de) | 1987-04-21 | 1987-04-21 | Stabile Lösungsmitteladdukte von Z-1-(p-beta-Dimethylamino-ethoxyphenyl)-1-(p-hydroxyphenyl)-2-phenylbut-1-en |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK189888D0 true DK189888D0 (da) | 1988-04-07 |
| DK189888A DK189888A (da) | 1988-10-22 |
| DK171748B1 DK171748B1 (da) | 1997-05-05 |
Family
ID=8196934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK189888A DK171748B1 (da) | 1987-04-21 | 1988-04-07 | Stabile opløsningsmiddeladdukter, fremgangsmåde til fremstilling deraf, lægemiddel indeholdende addukterne samt anvendelse af addukterne |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4973755A (da) |
| EP (1) | EP0287690B1 (da) |
| JP (1) | JP2596446B2 (da) |
| KR (1) | KR940010274B1 (da) |
| AR (1) | AR243494A1 (da) |
| AT (1) | ATE80152T1 (da) |
| AU (1) | AU607198B2 (da) |
| CA (1) | CA1305972C (da) |
| DE (1) | DE3781546D1 (da) |
| DK (1) | DK171748B1 (da) |
| ES (1) | ES2044860T3 (da) |
| GR (1) | GR3005582T3 (da) |
| HU (1) | HU204501B (da) |
| IE (1) | IE62488B1 (da) |
| IL (1) | IL85804A (da) |
| NZ (1) | NZ224296A (da) |
| PT (1) | PT87268B (da) |
| ZA (1) | ZA882016B (da) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5770609A (en) * | 1993-01-28 | 1998-06-23 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
| US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
| US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| DE69435137D1 (de) * | 1993-05-13 | 2008-10-16 | Poniard Pharmaceuticals Inc | Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind |
| KR0169186B1 (ko) * | 1993-10-25 | 1999-03-20 | 고바야시 유끼오 | 트리페닐에틸렌 화합물의 z이성체 산부가염의 제조방법 |
| DE4407742C1 (de) * | 1994-03-08 | 1995-06-22 | Hexal Pharma Gmbh | Transdermales System in Form eines Pflasters mit einem Tamoxifen-Derivat |
| US5650425A (en) * | 1994-04-04 | 1997-07-22 | Pharmos Corporation | Permanently ionic derivatives of steroid hormones and their antagonists |
| JPH11510479A (ja) | 1995-06-07 | 1999-09-14 | ネオルックス コーポレイション | タモキシフェン類似体による心臓血管疾病の予防及び治療 |
| GB9601167D0 (en) * | 1996-01-20 | 1996-03-20 | Univ Bradford | Tamoxifen and analogues thereof |
| HUP9900951A3 (en) | 1996-01-20 | 2000-02-28 | Bradford University Bradford | Process for producing tamoxifen and analogues thereof |
| US6083990A (en) | 1997-04-02 | 2000-07-04 | Pharmos Corporation | Enhanced anti-angiogenic activity of permanently charged derivatives of steroid hormones |
| US6117911A (en) * | 1997-04-11 | 2000-09-12 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
| GB9715479D0 (en) * | 1997-07-23 | 1997-10-01 | Univ Bradford | Tamoxifen and analogues thereof |
| JP2001527037A (ja) * | 1997-12-23 | 2001-12-25 | ヘキサル アーゲー | Ｚ−４−ヒドロキシタモキシフェン及びシクロデキストリンを含む混合物及び薬剤学的組成 |
| DE60327363D1 (de) * | 2002-12-18 | 2009-06-04 | Besins Int Lab | Verringerung der dichte des brustgewebes durch 4-hydroxy tamoxifen |
| AU2003303033B2 (en) * | 2002-12-18 | 2009-06-04 | Besins Healthcare Luxembourg Sarl | Treatment of mastalgia with 4-hydroxy tamoxifen |
| AU2003294973B2 (en) * | 2002-12-18 | 2010-05-13 | Besins Healthcare Luxembourg Sarl | Prevention and treatment of breast cancer with 4-hydroxy tamoxifen |
| CA2528431C (en) * | 2003-06-09 | 2012-09-18 | Northwestern University | Treatment and prevention of excessive scarring with 4-hydroxy tamoxifen |
| AU2004249295A1 (en) * | 2003-06-20 | 2004-12-29 | Viral Genomix, Inc. | Compositions for and methods for treating HIV |
| US7968532B2 (en) * | 2003-12-15 | 2011-06-28 | Besins Healthcare Luxembourg | Treatment of gynecomastia with 4-hydroxy tamoxifen |
| EP1579856A1 (en) * | 2004-03-22 | 2005-09-28 | Laboratoires Besins International | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| US7507769B2 (en) * | 2004-03-22 | 2009-03-24 | Laboratoires Besins International | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| PT1748770E (pt) * | 2004-03-22 | 2008-07-16 | Besins Int Lab | Tratamento e prevenção de doença benigna da mama com 4-hidroxi-tamoxifeno |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE637389A (da) * | 1962-09-13 | |||
| GB1099093A (en) * | 1965-09-03 | 1968-01-17 | Ici Ltd | Alkene derivatives |
| GB1560274A (en) * | 1977-02-28 | 1980-02-06 | Ici Ltd | Phenylbut 1-ene derivatives having antiostrogenicactivity |
| DE2860900D1 (en) * | 1977-08-22 | 1981-11-05 | Ici Plc | Triphenylalkene derivatives, process for their preparation and pharmaceutical compositions containing them |
| DE3046719C2 (de) * | 1980-12-11 | 1983-02-17 | Klinge Pharma GmbH, 8000 München | 1,1,2-Triphenyl-but-1-en-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel |
| DE3239610A1 (de) * | 1982-10-26 | 1984-04-26 | Klinge Pharma GmbH, 8000 München | Neue 1,1,2-triphenyl-but-l-en-derivate, sowie verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
-
1987
- 1987-04-21 AT AT87105803T patent/ATE80152T1/de not_active IP Right Cessation
- 1987-04-21 EP EP87105803A patent/EP0287690B1/de not_active Expired - Lifetime
- 1987-04-21 DE DE8787105803T patent/DE3781546D1/de not_active Expired - Fee Related
- 1987-04-21 ES ES87105803T patent/ES2044860T3/es not_active Expired - Lifetime
-
1988
- 1988-03-21 IL IL85804A patent/IL85804A/xx not_active IP Right Cessation
- 1988-03-22 ZA ZA882016A patent/ZA882016B/xx unknown
- 1988-03-25 CA CA000562434A patent/CA1305972C/en not_active Expired - Lifetime
- 1988-03-28 AU AU13798/88A patent/AU607198B2/en not_active Ceased
- 1988-04-07 DK DK189888A patent/DK171748B1/da not_active IP Right Cessation
- 1988-04-12 AR AR88310542A patent/AR243494A1/es active
- 1988-04-15 JP JP63093309A patent/JP2596446B2/ja not_active Expired - Fee Related
- 1988-04-18 HU HU881980A patent/HU204501B/hu not_active IP Right Cessation
- 1988-04-19 US US07/183,068 patent/US4973755A/en not_active Expired - Lifetime
- 1988-04-19 PT PT87268A patent/PT87268B/pt not_active IP Right Cessation
- 1988-04-19 IE IE117288A patent/IE62488B1/en not_active IP Right Cessation
- 1988-04-19 KR KR1019880004433A patent/KR940010274B1/ko not_active IP Right Cessation
- 1988-04-19 NZ NZ224296A patent/NZ224296A/xx unknown
-
1992
- 1992-09-03 GR GR920401142T patent/GR3005582T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6445347A (en) | 1989-02-17 |
| AR243494A1 (es) | 1993-08-31 |
| HU204501B (en) | 1992-01-28 |
| ATE80152T1 (de) | 1992-09-15 |
| GR3005582T3 (da) | 1993-06-07 |
| ZA882016B (en) | 1988-12-28 |
| KR880012528A (ko) | 1988-11-28 |
| KR940010274B1 (ko) | 1994-10-22 |
| ES2044860T3 (es) | 1994-01-16 |
| CA1305972C (en) | 1992-08-04 |
| DK189888A (da) | 1988-10-22 |
| EP0287690B1 (de) | 1992-09-02 |
| DK171748B1 (da) | 1997-05-05 |
| PT87268A (pt) | 1988-05-01 |
| AU607198B2 (en) | 1991-02-28 |
| HUT50318A (en) | 1990-01-29 |
| JP2596446B2 (ja) | 1997-04-02 |
| IL85804A (en) | 1991-07-18 |
| IL85804A0 (en) | 1988-09-30 |
| PT87268B (pt) | 1992-08-31 |
| EP0287690A1 (de) | 1988-10-26 |
| NZ224296A (en) | 1990-02-26 |
| DE3781546D1 (de) | 1992-10-08 |
| US4973755A (en) | 1990-11-27 |
| AU1379888A (en) | 1988-10-20 |
| IE62488B1 (en) | 1995-02-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |
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