DK18082A - Fremgangsmaade til fremstilling af cycloheptenderivater - Google Patents

Fremgangsmaade til fremstilling af cycloheptenderivater Download PDF

Info

Publication number
DK18082A
DK18082A DK18082A DK18082A DK18082A DK 18082 A DK18082 A DK 18082A DK 18082 A DK18082 A DK 18082A DK 18082 A DK18082 A DK 18082A DK 18082 A DK18082 A DK 18082A
Authority
DK
Denmark
Prior art keywords
cycloheptend
derivatives
procedure
preparation
compounds
Prior art date
Application number
DK18082A
Other languages
English (en)
Inventor
W Aschwanden
Q Branca
E Kyburz
R Pfister
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK18082A publication Critical patent/DK18082A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
    • C07C2603/32—Dibenzocycloheptenes; Hydrogenated dibenzocycloheptenes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

lus, og farmaceutisk tolerable syreadditionssalte deraf har værdifulde histamin-H^-antagonistiske egenskaber og kan anvendes til bekæmpelse eller forebyggelse af allergiske reaktioner såsom urticaria, høfeber, anafylaksi og lægemiddeloverfølsomhed.
Forbindelserne I fremstilles ved forskellige fremgangsmåder, bl.a. ud fra hidtil ukendte forbindelser med den almene formel III og V
Figure DK18082AD00021
hvor X betegner en fraspaltelig enhed.
DK18082A 1981-01-16 1982-01-15 Fremgangsmaade til fremstilling af cycloheptenderivater DK18082A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH27481 1981-01-16
CH27481 1981-01-16

Publications (1)

Publication Number Publication Date
DK18082A true DK18082A (da) 1982-07-17

Family

ID=4183267

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18082A DK18082A (da) 1981-01-16 1982-01-15 Fremgangsmaade til fremstilling af cycloheptenderivater

Country Status (7)

Country Link
EP (1) EP0056616B1 (da)
JP (1) JPS57139022A (da)
AU (1) AU546906B2 (da)
CA (1) CA1160219A (da)
DE (1) DE3265480D1 (da)
DK (1) DK18082A (da)
ZA (1) ZA82138B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8502099A1 (es) * 1983-08-02 1984-12-16 Espanola Farma Therapeut Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina.
IT1222986B (it) * 1987-10-23 1990-09-12 Texcontor Ets Derivati dell'efedrina esterificata aventi attivita' antiulcera prolungata nel tempo

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3409640A (en) * 1959-07-22 1968-11-05 Schering Corp 5-(3'-dimethylamino-2'-methyl-propyl)dibenzocycloheptenes
GB1017696A (en) * 1961-09-25 1966-01-19 Merck & Co Inc Substituted 5h-dibenzo[a, d]cycloheptenes and 10,11-dihydro-5h-dibenzo[a, d]cycloheptenes
CH513807A (de) * 1968-05-03 1971-10-15 Hoffmann La Roche Verfahren zur Herstellung von tricyclischen Verbindungen

Also Published As

Publication number Publication date
CA1160219A (en) 1984-01-10
DE3265480D1 (en) 1985-09-26
EP0056616A2 (de) 1982-07-28
EP0056616B1 (de) 1985-08-21
AU7941782A (en) 1982-07-22
EP0056616A3 (en) 1982-10-27
JPS57139022A (en) 1982-08-27
ZA82138B (en) 1982-11-24
AU546906B2 (en) 1985-09-26

Similar Documents

Publication Publication Date Title
DK158307C (da) Analogifremgangsmaade til fremstilling af 4-(fenylalkyl)-imidazolderivater eller farmaceutisk acceptable syreadditionssalte deraf
DE2117571B2 (de) Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
CH649527A5 (de) 1,2-diaminocyclobuten-3,4-dione, verfahren zu deren herstellung und pharmazeutische mittel, die diese verbindungen enthalten.
DE3105330C2 (da)
EP0148499A3 (de) Substituierte Malonsäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
DD216929A5 (de) Verfahren zur herstellung von thiazolidinderivaten
DE3331808A1 (de) Carbostyrilderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten
EP0277384A3 (en) 1h-imidazole-5-carboxylic acid derivatives
DE3240727A1 (de) Ergolinderivate, verfahren zu deren herstellung sowie pharmazeutische zubereitungen, die diese enthalten
EP0330939A3 (en) Acrylic acid morpholides, their production and use
EP0216360A3 (de) Imidazolinyl-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Mittel mit herbizider Wirkung
DE2619724C2 (de) 2-(Phenylimino)-thiazoline
DE1595992A1 (de) Neue 3-Chlor-4-cyan-isothiazole und diese enthaltende insektizide Mittel
DE3216843C2 (de) 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DK18082A (da) Fremgangsmaade til fremstilling af cycloheptenderivater
EP0300313A3 (de) Substituierte Triazine
DE19842833B4 (de) 2-Arylalkylthio-imidazole, 2-Arylalkenylthio-imidazole und 2-Arylalkinylthio-imidazole als Entzündungs-Hemmstoffe und Hemmstoffe der Cytokin-Freisetzung
DE2719246C2 (de) Dimaleat von 1[2(4-Methoxybenzhydryloxyäthyl)]-4-[3(4-fluorbenzoyl)-propyl]-piperazin, Verfahren zu dessen Herstellung und diese Verbindung enthaltendes Arzneimittel
EP0236838A3 (de) Aminoester-Dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung
DE3142559A1 (de) "pyrimidin-derivate"
DE1934392C3 (de) Neue 2-Pyridylthioamide und Verfahren zu ihrer Herstellung
DE69012451T2 (de) Cyanoguanidin-Derivate.
EP0081206A3 (de) Anilinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Bekämpfung unerwünschten Pflanzenwuchses
DE2316721A1 (de) Neue salze von biguaniden und verfahren zu ihrer herstellung
EP0244595A3 (de) Dihydropyridinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment