DK18082A - PROCEDURE FOR THE PREPARATION OF CYCLOHEPTEND DERIVATIVES - Google Patents

PROCEDURE FOR THE PREPARATION OF CYCLOHEPTEND DERIVATIVES Download PDF

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Publication number
DK18082A
DK18082A DK18082A DK18082A DK18082A DK 18082 A DK18082 A DK 18082A DK 18082 A DK18082 A DK 18082A DK 18082 A DK18082 A DK 18082A DK 18082 A DK18082 A DK 18082A
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DK
Denmark
Prior art keywords
cycloheptend
derivatives
procedure
preparation
compounds
Prior art date
Application number
DK18082A
Other languages
Danish (da)
Inventor
W Aschwanden
Q Branca
E Kyburz
R Pfister
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK18082A publication Critical patent/DK18082A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
    • C07C2603/32—Dibenzocycloheptenes; Hydrogenated dibenzocycloheptenes

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

lus, og farmaceutisk tolerable syreadditionssalte deraf har værdifulde histamin-H^-antagonistiske egenskaber og kan anvendes til bekæmpelse eller forebyggelse af allergiske reaktioner såsom urticaria, høfeber, anafylaksi og lægemiddeloverfølsomhed.lice, and pharmaceutically tolerable acid addition salts thereof, have valuable histamine H 2 antagonistic properties and can be used to control or prevent allergic reactions such as urticaria, hay fever, anaphylaxis and drug hypersensitivity.

Forbindelserne I fremstilles ved forskellige fremgangsmåder, bl.a. ud fra hidtil ukendte forbindelser med den almene formel III og VThe compounds I are prepared by various methods, e.g. from novel compounds of general formulas III and V

Figure DK18082AD00021

hvor X betegner en fraspaltelig enhed.where X represents a leaving unit.

DK18082A 1981-01-16 1982-01-15 PROCEDURE FOR THE PREPARATION OF CYCLOHEPTEND DERIVATIVES DK18082A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH27481 1981-01-16
CH27481 1981-01-16

Publications (1)

Publication Number Publication Date
DK18082A true DK18082A (en) 1982-07-17

Family

ID=4183267

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18082A DK18082A (en) 1981-01-16 1982-01-15 PROCEDURE FOR THE PREPARATION OF CYCLOHEPTEND DERIVATIVES

Country Status (7)

Country Link
EP (1) EP0056616B1 (en)
JP (1) JPS57139022A (en)
AU (1) AU546906B2 (en)
CA (1) CA1160219A (en)
DE (1) DE3265480D1 (en)
DK (1) DK18082A (en)
ZA (1) ZA82138B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8502099A1 (en) * 1983-08-02 1984-12-16 Espanola Farma Therapeut Derivatives of dihydrodibenzocycloheptylidene-ethylamine.
IT1222986B (en) * 1987-10-23 1990-09-12 Texcontor Ets ESTERIFIED EPHEDRINE DERIVATIVES HAVING AN EXTENDED ANTI-ULTER ACTIVITY OVER TIME

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3409640A (en) * 1959-07-22 1968-11-05 Schering Corp 5-(3'-dimethylamino-2'-methyl-propyl)dibenzocycloheptenes
GB1017696A (en) * 1961-09-25 1966-01-19 Merck & Co Inc Substituted 5h-dibenzo[a, d]cycloheptenes and 10,11-dihydro-5h-dibenzo[a, d]cycloheptenes
CH513807A (en) * 1968-05-03 1971-10-15 Hoffmann La Roche Tricyclic cpds antidepressive

Also Published As

Publication number Publication date
EP0056616B1 (en) 1985-08-21
JPS57139022A (en) 1982-08-27
AU7941782A (en) 1982-07-22
EP0056616A2 (en) 1982-07-28
CA1160219A (en) 1984-01-10
DE3265480D1 (en) 1985-09-26
AU546906B2 (en) 1985-09-26
EP0056616A3 (en) 1982-10-27
ZA82138B (en) 1982-11-24

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