DK1797088T3 - Hidtil ukendte chromen-2-on-derivater og anvendelse heraf som monoamin-neurotransmitter-genoptagelseshæmmere - Google Patents
Hidtil ukendte chromen-2-on-derivater og anvendelse heraf som monoamin-neurotransmitter-genoptagelseshæmmereInfo
- Publication number
- DK1797088T3 DK1797088T3 DK05792113.2T DK05792113T DK1797088T3 DK 1797088 T3 DK1797088 T3 DK 1797088T3 DK 05792113 T DK05792113 T DK 05792113T DK 1797088 T3 DK1797088 T3 DK 1797088T3
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- reuptake inhibitors
- monoamine neurotransmitter
- neurotransmitter reuptake
- novel chromium
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/12—Oxygen atoms acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Gynecology & Obstetrics (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Developing Agents For Electrophotography (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61405204P | 2004-09-30 | 2004-09-30 | |
DKPA200401491 | 2004-09-30 | ||
PCT/EP2005/054861 WO2006035034A1 (en) | 2004-09-30 | 2005-09-28 | Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1797088T3 true DK1797088T3 (da) | 2011-04-04 |
Family
ID=43448525
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK05792113.2T DK1797088T3 (da) | 2004-09-30 | 2005-09-28 | Hidtil ukendte chromen-2-on-derivater og anvendelse heraf som monoamin-neurotransmitter-genoptagelseshæmmere |
Country Status (14)
Country | Link |
---|---|
US (1) | US7696350B2 (da) |
EP (2) | EP2284170A1 (da) |
JP (1) | JP5001156B2 (da) |
CN (1) | CN101023081A (da) |
AT (1) | ATE494286T1 (da) |
AU (1) | AU2005288914B2 (da) |
BR (1) | BRPI0515261A (da) |
CA (1) | CA2582297A1 (da) |
DE (1) | DE602005025785D1 (da) |
DK (1) | DK1797088T3 (da) |
NZ (1) | NZ552919A (da) |
PL (1) | PL1797088T3 (da) |
RU (1) | RU2382040C2 (da) |
WO (1) | WO2006035034A1 (da) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20070061846A (ko) * | 2004-09-30 | 2007-06-14 | 뉴로서치 에이/에스 | 신규한 크로멘-2-온 유도체 및 모노아민 신경전달물질재흡수 억제제로서의 이의 용도 |
TW200800980A (en) * | 2006-02-17 | 2008-01-01 | Neurosearch As | Novel compounds |
TW200836732A (en) * | 2006-12-20 | 2008-09-16 | Neurosearch As | Novel compounds |
CA2673315A1 (en) * | 2006-12-20 | 2008-06-26 | Neurosearch A/S | Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
AU2007336291A1 (en) * | 2006-12-20 | 2008-06-26 | Neurosearch A/S | Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
TW200904815A (en) * | 2007-05-09 | 2009-02-01 | Neurosearch As | Novel compounds |
US20100286134A1 (en) * | 2007-09-10 | 2010-11-11 | Neurosearch A/S | Novel phenoxazin-3-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
US20100286195A1 (en) * | 2007-09-10 | 2010-11-11 | Neurosearch A/S | Novel benzooxazol-and benzooxathiol-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
EP2242754A1 (en) * | 2008-02-05 | 2010-10-27 | NeuroSearch A/S | Novel 9-aza-bicyclo[3.3.1]non-3-yloxy chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
CA2734797A1 (en) | 2008-08-21 | 2010-02-25 | Neurosearch A/S | Treatment of anxiety disorders |
AU2010247514A1 (en) | 2009-05-15 | 2011-11-17 | Neurosearch A/S | Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
US20130040985A1 (en) | 2010-01-29 | 2013-02-14 | Neurosearch A/S | Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
WO2011117289A1 (en) | 2010-03-25 | 2011-09-29 | Neurosearch A/S | Chromen-2-one derivatives and their use as monoamine neuro-transmitter re-uptake inhibitors |
WO2012000881A1 (en) | 2010-07-02 | 2012-01-05 | Neurosearch A/S | Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
DK4009942T3 (da) * | 2019-08-06 | 2023-10-23 | Initiator Pharma As | Forbindelse til kombinationsbehandling |
WO2024146892A1 (en) * | 2023-01-03 | 2024-07-11 | Initiator Pharma A/S | Compound for treatment of erectile dysfunction |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2189027B1 (da) * | 1972-06-21 | 1976-03-05 | Leurquin Laboratoires Fr | |
PL187175B1 (pl) * | 1995-10-13 | 2004-05-31 | Bayer Cropscience Ltd | Bicykliczne związki heterocykliczne, kompozycja grzybobójcza je zawierająca i ich zastosowanie |
UA49872C2 (uk) | 1996-02-22 | 2002-10-15 | Н'Юросерч А/С | Похідні тропану, спосіб їх одержання, фармацевтична композиція та спосіб лікування |
WO2002102801A1 (en) * | 2001-05-23 | 2002-12-27 | Neurosearch A/S | Tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
WO2003106452A2 (en) * | 2002-06-12 | 2003-12-24 | Millennium Pharmaceuticals, Inc. | Antagonists of melanin concentrating hormone receptor |
US7538233B2 (en) * | 2003-09-05 | 2009-05-26 | Aventis Pharmaceuticals Inc. | Coumarins as iNOS inhibitors |
-
2005
- 2005-09-28 EP EP10180549A patent/EP2284170A1/en not_active Withdrawn
- 2005-09-28 RU RU2007106970/04A patent/RU2382040C2/ru not_active IP Right Cessation
- 2005-09-28 DE DE602005025785T patent/DE602005025785D1/de active Active
- 2005-09-28 AU AU2005288914A patent/AU2005288914B2/en not_active Ceased
- 2005-09-28 WO PCT/EP2005/054861 patent/WO2006035034A1/en active Application Filing
- 2005-09-28 BR BRPI0515261-5A patent/BRPI0515261A/pt not_active IP Right Cessation
- 2005-09-28 NZ NZ552919A patent/NZ552919A/en not_active IP Right Cessation
- 2005-09-28 PL PL05792113T patent/PL1797088T3/pl unknown
- 2005-09-28 CN CNA2005800317650A patent/CN101023081A/zh active Pending
- 2005-09-28 DK DK05792113.2T patent/DK1797088T3/da active
- 2005-09-28 CA CA002582297A patent/CA2582297A1/en not_active Abandoned
- 2005-09-28 US US11/661,966 patent/US7696350B2/en active Active
- 2005-09-28 EP EP05792113A patent/EP1797088B1/en active Active
- 2005-09-28 JP JP2007534018A patent/JP5001156B2/ja active Active
- 2005-09-28 AT AT05792113T patent/ATE494286T1/de active
Also Published As
Publication number | Publication date |
---|---|
ATE494286T1 (de) | 2011-01-15 |
CN101023081A (zh) | 2007-08-22 |
DE602005025785D1 (de) | 2011-02-17 |
PL1797088T3 (pl) | 2011-06-30 |
NZ552919A (en) | 2010-06-25 |
AU2005288914A1 (en) | 2006-04-06 |
WO2006035034A1 (en) | 2006-04-06 |
AU2005288914B2 (en) | 2011-05-19 |
EP2284170A1 (en) | 2011-02-16 |
RU2007106970A (ru) | 2008-11-10 |
EP1797088B1 (en) | 2011-01-05 |
JP5001156B2 (ja) | 2012-08-15 |
BRPI0515261A (pt) | 2008-07-15 |
CA2582297A1 (en) | 2006-04-06 |
JP2008514676A (ja) | 2008-05-08 |
US20070232666A1 (en) | 2007-10-04 |
RU2382040C2 (ru) | 2010-02-20 |
US7696350B2 (en) | 2010-04-13 |
EP1797088A1 (en) | 2007-06-20 |
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