DK1773986T3 - PRE-PRIMATIVE STRIP AND MESENDODERM CELLS - Google Patents

PRE-PRIMATIVE STRIP AND MESENDODERM CELLS Download PDF

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Publication number
DK1773986T3
DK1773986T3 DK05769491.1T DK05769491T DK1773986T3 DK 1773986 T3 DK1773986 T3 DK 1773986T3 DK 05769491 T DK05769491 T DK 05769491T DK 1773986 T3 DK1773986 T3 DK 1773986T3
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DK
Denmark
Prior art keywords
cells
human
cell
expression
cell culture
Prior art date
Application number
DK05769491.1T
Other languages
Danish (da)
English (en)
Inventor
Emmanuel E Baetge
Kevin Allen D'amour
Alan D Agulnick
Susan Eliazer
Evert Kroon
Original Assignee
Viacyte Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/021,618 external-priority patent/US7510876B2/en
Application filed by Viacyte Inc filed Critical Viacyte Inc
Application granted granted Critical
Publication of DK1773986T3 publication Critical patent/DK1773986T3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/16Activin; Inhibin; Mullerian inhibiting substance
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Reproductive Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
DK05769491.1T 2004-07-09 2005-07-08 PRE-PRIMATIVE STRIP AND MESENDODERM CELLS DK1773986T3 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US58656604P 2004-07-09 2004-07-09
US58794204P 2004-07-14 2004-07-14
US11/021,618 US7510876B2 (en) 2003-12-23 2004-12-23 Definitive endoderm
US69336405P 2005-06-23 2005-06-23
PCT/US2005/024161 WO2006017134A2 (en) 2004-07-09 2005-07-08 Preprimitive streak and mesendoderm cells

Publications (1)

Publication Number Publication Date
DK1773986T3 true DK1773986T3 (en) 2019-04-08

Family

ID=40262947

Family Applications (2)

Application Number Title Priority Date Filing Date
DK05769491.1T DK1773986T3 (en) 2004-07-09 2005-07-08 PRE-PRIMATIVE STRIP AND MESENDODERM CELLS
DK10013206T DK2341147T3 (da) 2004-07-09 2005-07-08 Præprimitive stribe- og mesendodermceller

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK10013206T DK2341147T3 (da) 2004-07-09 2005-07-08 Præprimitive stribe- og mesendodermceller

Country Status (10)

Country Link
EP (2) EP3505622A1 (enExample)
JP (7) JP5433879B2 (enExample)
CN (1) CN102586170B (enExample)
AU (1) AU2005271944B2 (enExample)
CA (1) CA2573354C (enExample)
DK (2) DK1773986T3 (enExample)
ES (2) ES2754038T3 (enExample)
MX (1) MX2007000317A (enExample)
NZ (1) NZ582597A (enExample)
WO (1) WO2006017134A2 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050266554A1 (en) 2004-04-27 2005-12-01 D Amour Kevin A PDX1 expressing endoderm
US7625753B2 (en) 2003-12-23 2009-12-01 Cythera, Inc. Expansion of definitive endoderm cells
US7985585B2 (en) 2004-07-09 2011-07-26 Viacyte, Inc. Preprimitive streak and mesendoderm cells
US7541185B2 (en) 2003-12-23 2009-06-02 Cythera, Inc. Methods for identifying factors for differentiating definitive endoderm
US8647873B2 (en) 2004-04-27 2014-02-11 Viacyte, Inc. PDX1 expressing endoderm
KR101221302B1 (ko) 2003-12-23 2013-01-11 비아싸이트, 인크. 완전 내배엽
WO2007059007A2 (en) 2005-11-14 2007-05-24 Cythera, Inc. Markers of definitive endoderm
EP1791952A4 (en) * 2004-08-13 2008-06-11 Univ Georgia Res Found COMPOSITIONS AND METHODS OF SELF-RENEWAL AND DIFFERENTIATION IN HUMAN EMBRYONAL STEM CELLS
AU2005322007B2 (en) * 2004-12-23 2011-06-30 Viacyte, Inc. Expansion of definitive endoderm cells
FI20055398A0 (fi) 2005-07-08 2005-07-08 Suomen Punainen Risti Veripalv Menetelmä solupopulaatioiden evaluoimiseksi
EP3584311A1 (en) 2005-10-27 2019-12-25 Viacyte, Inc. Pdx-1 expressing dorsal and ventral foregut endoderm
EP1994141B1 (en) 2006-02-23 2017-11-15 ViaCyte, Inc. Compositions and methods useful for culturing differentiable cells
US11254916B2 (en) 2006-03-02 2022-02-22 Viacyte, Inc. Methods of making and using PDX1-positive pancreatic endoderm cells
US7695965B2 (en) 2006-03-02 2010-04-13 Cythera, Inc. Methods of producing pancreatic hormones
CA2644468C (en) 2006-03-02 2022-02-01 Cythera, Inc. Endocrine precursor cells, pancreatic hormone-expressing cells and methods of production
AU2007277364B2 (en) 2006-07-26 2010-08-12 Viacyte, Inc. Methods of producing pancreatic hormones
US20100323442A1 (en) * 2006-10-17 2010-12-23 Emmanuel Edward Baetge Modulation of the phosphatidylinositol-3-kinase pathway in the differentiation of human embryonic stem cells
US7695963B2 (en) 2007-09-24 2010-04-13 Cythera, Inc. Methods for increasing definitive endoderm production
US8008075B2 (en) 2008-11-04 2011-08-30 Viacyte, Inc. Stem cell aggregate suspension compositions and methods of differentiation thereof
US8895300B2 (en) 2008-11-04 2014-11-25 Viacyte, Inc. Scalable primate pluripotent stem cell aggregate suspension culture and differentiation thereof
EP3363444B1 (en) 2008-11-14 2022-09-14 ViaCyte, Inc. Encapsulation of pancreatic cells derived from human pluripotent stem cells
EP2367931B1 (en) * 2008-12-03 2017-05-31 International Stem Cell Corporation Methods of deriving differentiated cells from stem cells
AU2020283056B2 (en) 2019-05-31 2023-06-08 Viacyte, Inc. A biocompatible membrane composite
CA3139591C (en) 2019-05-31 2024-01-16 Timothy M. BRUHN A biocompatible membrane composite
EP3976237A1 (en) 2019-05-31 2022-04-06 W.L. Gore & Associates Inc. Cell encapsulation devices with controlled oxygen diffusion distances
EP3975926A1 (en) 2019-05-31 2022-04-06 W.L. Gore & Associates, Inc. A biocompatible membrane composite
CA3190604A1 (en) 2020-08-15 2022-02-24 Regeneron Pharmaceuticals, Inc. Treatment of obesity in subjects having variant nucleic acid molecules encoding calcitonin receptor (calcr)

Family Cites Families (24)

* Cited by examiner, † Cited by third party
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US2161804A (en) 1935-11-09 1939-06-13 Baldwin Southwark Corp Hydraulic press
US5453357A (en) 1992-10-08 1995-09-26 Vanderbilt University Pluripotential embryonic stem cells and methods of making same
US5690926A (en) 1992-10-08 1997-11-25 Vanderbilt University Pluripotential embryonic cells and methods of making same
US5843780A (en) 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
JP2001517927A (ja) 1996-02-28 2001-10-09 バンダービルト ユニバーシティ 胚幹細胞を作製する組成物および方法
AU728541B2 (en) * 1996-10-07 2001-01-11 Johns Hopkins University School Of Medicine, The Novel hedgehog-derived polypeptides
WO1998037195A1 (en) * 1997-02-19 1998-08-27 Regeneron Pharmaceuticals, Inc. Morphogenic proteins
US6331406B1 (en) * 1997-03-31 2001-12-18 The John Hopkins University School Of Medicine Human enbryonic germ cell and methods of use
US6090622A (en) 1997-03-31 2000-07-18 The Johns Hopkins School Of Medicine Human embryonic pluripotent germ cells
US6075007A (en) * 1997-07-17 2000-06-13 Regeneron Pharmaceuticals, Inc. Modified noggin polypeptide and compositions
EP1025204A4 (en) 1997-10-23 2001-02-28 Geron Corp Methods and materials for the growth of primate-derived primordial stem cells
US6667176B1 (en) 2000-01-11 2003-12-23 Geron Corporation cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
JP2000217571A (ja) * 1999-01-29 2000-08-08 Japan Science & Technology Corp インビトロで誘導した移植用臓器
US7005252B1 (en) 2000-03-09 2006-02-28 Wisconsin Alumni Research Foundation Serum free cultivation of primate embryonic stem cells
US6458589B1 (en) * 2000-04-27 2002-10-01 Geron Corporation Hepatocyte lineage cells derived from pluripotent stem cells
AU8617301A (en) * 2000-08-01 2002-02-13 Yissum Res Dev Co Directed differentiation of embryonic cells
WO2003046141A2 (en) * 2001-11-26 2003-06-05 Advanced Cell Technology, Inc. Methods for making and using reprogrammed human somatic cell nuclei and autologous and isogenic human stem cells
GB2399823B (en) * 2001-12-07 2006-02-15 Geron Corp Islet cells from primate pluripotent stem cells
WO2003089619A2 (en) * 2002-04-19 2003-10-30 University Of Pittsburgh Of The Commonwealth System Of Higher Education Placental derived stem cells and uses thereof
WO2004098490A2 (en) * 2002-05-17 2004-11-18 Mount Sinai School Of Medicine Of New York University Mesoderm and definitive endoderm cell populations
US20040229350A1 (en) 2003-05-12 2004-11-18 Nikolai Strelchenko Morula derived embryonic stem cells
KR101221302B1 (ko) * 2003-12-23 2013-01-11 비아싸이트, 인크. 완전 내배엽
EP1791952A4 (en) * 2004-08-13 2008-06-11 Univ Georgia Res Found COMPOSITIONS AND METHODS OF SELF-RENEWAL AND DIFFERENTIATION IN HUMAN EMBRYONAL STEM CELLS
US11586805B2 (en) 2021-07-26 2023-02-21 Atlassian Pty Ltd. Machine-learning-based natural language processing techniques for low-latency document summarization

Also Published As

Publication number Publication date
JP6473708B2 (ja) 2019-02-20
NZ582597A (en) 2011-08-26
JP2020103321A (ja) 2020-07-09
MX2007000317A (es) 2007-03-26
CN102586170A (zh) 2012-07-18
EP1773986B1 (en) 2019-01-16
JP7525102B2 (ja) 2024-07-30
JP6777620B2 (ja) 2020-10-28
ES2754038T3 (es) 2020-04-15
JP2018027099A (ja) 2018-02-22
EP1773986A2 (en) 2007-04-18
JP6077044B2 (ja) 2017-02-08
ES2716827T3 (es) 2019-06-17
JP2015130889A (ja) 2015-07-23
JP7161665B2 (ja) 2022-10-27
JP2013212121A (ja) 2013-10-17
JP2022142795A (ja) 2022-09-30
AU2005271944B2 (en) 2012-02-16
JP2008505643A (ja) 2008-02-28
WO2006017134A3 (en) 2007-01-18
EP3505622A1 (en) 2019-07-03
JP5433879B2 (ja) 2014-03-05
CA2573354C (en) 2015-02-24
JP2016119919A (ja) 2016-07-07
CA2573354A1 (en) 2006-02-16
JP5956388B2 (ja) 2016-07-27
DK2341147T3 (da) 2019-11-11
AU2005271944A1 (en) 2006-02-16
WO2006017134A2 (en) 2006-02-16
CN102586170B (zh) 2019-11-29

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