DK1771572T3 - P75NTR-screeningsassay for identifikation af modulatorer af apoptose - Google Patents

P75NTR-screeningsassay for identifikation af modulatorer af apoptose

Info

Publication number
DK1771572T3
DK1771572T3 DK05766804T DK05766804T DK1771572T3 DK 1771572 T3 DK1771572 T3 DK 1771572T3 DK 05766804 T DK05766804 T DK 05766804T DK 05766804 T DK05766804 T DK 05766804T DK 1771572 T3 DK1771572 T3 DK 1771572T3
Authority
DK
Denmark
Prior art keywords
apoptosis
p75ntr
modulators
identification
screening assay
Prior art date
Application number
DK05766804T
Other languages
Danish (da)
English (en)
Inventor
Wouter David Bruinzeel
Miroslav Cik
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1771572T3 publication Critical patent/DK1771572T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5058Neurological cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2510/00Detection of programmed cell death, i.e. apoptosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK05766804T 2004-07-14 2005-07-11 P75NTR-screeningsassay for identifikation af modulatorer af apoptose DK1771572T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04103368 2004-07-14
US58855104P 2004-07-16 2004-07-16
PCT/EP2005/053304 WO2006005740A2 (fr) 2004-07-14 2005-07-11 Essai de depistage de p75ntr

Publications (1)

Publication Number Publication Date
DK1771572T3 true DK1771572T3 (da) 2009-02-16

Family

ID=39243741

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05766804T DK1771572T3 (da) 2004-07-14 2005-07-11 P75NTR-screeningsassay for identifikation af modulatorer af apoptose

Country Status (9)

Country Link
US (1) US8637464B2 (fr)
EP (1) EP1771572B1 (fr)
AT (1) ATE411393T1 (fr)
AU (1) AU2005261721B2 (fr)
CA (1) CA2571130C (fr)
DE (1) DE602005010436D1 (fr)
DK (1) DK1771572T3 (fr)
ES (1) ES2315889T3 (fr)
WO (1) WO2006005740A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011163241A2 (fr) * 2010-06-21 2011-12-29 Georgetown University Composés neuroprotecteurs
WO2014049556A2 (fr) * 2012-09-28 2014-04-03 The University Of Queensland Signalisation des récepteurs de neurotrophine-tyrosine kinase
EP2950095B1 (fr) * 2014-05-28 2018-08-29 Technische Universität Dresden Analyse cellulaire et procédés de criblage de modulateurs de signalisation de p75NTR
IT202000007720A1 (it) * 2020-04-10 2021-10-10 Alessandra Marconi Peptidi e loro usi

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU689248B2 (en) * 1994-04-11 1998-03-26 Nexins Research B.V. A method for detecting and/or optionally quantifying and/or separating apoptotic cells in or from a sample
ATE408688T1 (de) * 1998-10-06 2008-10-15 Univ Queensland Polypeptide zur modulierung des überlebens von zellen
FR2801320B1 (fr) * 1999-11-19 2002-02-15 Inst Nat Sante Rech Med Procede d'evaluation de la genotoxicite d'un compose
US6881719B2 (en) 2000-01-18 2005-04-19 Mcgill University β-turn peptidomimetic cyclic compounds

Also Published As

Publication number Publication date
ES2315889T3 (es) 2009-04-01
CA2571130C (fr) 2014-08-19
EP1771572B1 (fr) 2008-10-15
CA2571130A1 (fr) 2006-01-19
US8637464B2 (en) 2014-01-28
WO2006005740A3 (fr) 2006-06-29
WO2006005740A2 (fr) 2006-01-19
EP1771572A2 (fr) 2007-04-11
US20080064036A1 (en) 2008-03-13
AU2005261721B2 (en) 2011-02-24
ATE411393T1 (de) 2008-10-15
DE602005010436D1 (de) 2008-11-27
AU2005261721A1 (en) 2006-01-19

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