DK1756571T3 - Fremgangsmåde i realtid til detektering af akut inflammatoriske tilstande - Google Patents

Fremgangsmåde i realtid til detektering af akut inflammatoriske tilstande

Info

Publication number
DK1756571T3
DK1756571T3 DK05776689.1T DK05776689T DK1756571T3 DK 1756571 T3 DK1756571 T3 DK 1756571T3 DK 05776689 T DK05776689 T DK 05776689T DK 1756571 T3 DK1756571 T3 DK 1756571T3
Authority
DK
Denmark
Prior art keywords
real
inflammatory conditions
acute inflammatory
time method
detecting acute
Prior art date
Application number
DK05776689.1T
Other languages
English (en)
Inventor
Joseph M Ahearn
Susan M Manzi
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Application granted granted Critical
Publication of DK1756571T3 publication Critical patent/DK1756571T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4716Complement proteins, e.g. anaphylatoxin, C3a, C5a
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • G01N2800/101Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/104Lupus erythematosus [SLE]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/811Test for named disease, body condition or organ function

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Washing And Drying Of Tableware (AREA)
DK05776689.1T 2004-04-09 2005-04-08 Fremgangsmåde i realtid til detektering af akut inflammatoriske tilstande DK1756571T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56098604P 2004-04-09 2004-04-09
US57962104P 2004-06-14 2004-06-14
PCT/US2005/011914 WO2005108988A2 (en) 2004-04-09 2005-04-08 Real time method of detecting acute inflammatory conditions

Publications (1)

Publication Number Publication Date
DK1756571T3 true DK1756571T3 (da) 2010-12-13

Family

ID=35320843

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05776689.1T DK1756571T3 (da) 2004-04-09 2005-04-08 Fremgangsmåde i realtid til detektering af akut inflammatoriske tilstande

Country Status (9)

Country Link
US (1) US7361517B2 (da)
EP (2) EP2216650A1 (da)
JP (1) JP2007532885A (da)
AT (1) ATE478335T1 (da)
AU (1) AU2005241415A1 (da)
CA (1) CA2561684A1 (da)
DE (1) DE602005023009D1 (da)
DK (1) DK1756571T3 (da)
WO (1) WO2005108988A2 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4550051B2 (ja) * 2003-04-16 2010-09-22 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 全身性エリテマトーデスの同定およびモニタリング
AU2005242719B2 (en) * 2004-05-11 2011-02-24 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Diagnosing and monitoring inflammatory diseases by measuring complement components on white blood cells
WO2006035024A1 (en) * 2004-09-29 2006-04-06 Mellitus, S.L. Method for detecting a predisposition to develop gestational diabetes mellitus and treatment for this disease
EP2347259A4 (en) * 2008-10-16 2012-02-29 Cypress Bioscience Inc METHOD FOR DIAGNOSIS AND MONITORING OF ILLICIT ACTIVITY AND RESPONSE TO TREATMENT IN SYSTEMIC LUPUS ERYTHEMATODES (SLE) AND OTHER AUTOIMMUNE DISEASES
US8574851B2 (en) * 2008-11-24 2013-11-05 Corthera, Inc. Prediction and prevention of preeclampsia
CN103261893A (zh) * 2010-11-29 2013-08-21 诺沃姆德治疗公司 用于诊断组织损害的新抗体
EP2673644B1 (en) 2011-02-11 2016-02-10 Exagen Diagnostics, Inc. Methods for diagnosing systemic lupus erythematosus
CA2877441A1 (en) 2012-07-02 2014-01-09 Medizinische Universitat Wien Complement split product c4d for the treatment of inflammatory conditions
RU2019103573A (ru) * 2013-02-08 2019-03-15 Аллегени-Сингер Рисерч Инститьют Клеточно-связанные продукты активации комплемента в качестве диагностических биомаркеров волчанки в доклинической стадии
CA2901551A1 (en) * 2013-03-14 2014-09-25 Immucor Gti Diagnostics, Inc. Methods and compositions for diagnosing preeclampsia
JP6453299B2 (ja) 2013-03-15 2019-01-16 エグザゲン ダイアグノスティクス,インコーポレイテッド 全身性エリテマトーデスを治療および診断するための方法
WO2016023006A1 (en) * 2014-08-08 2016-02-11 Allegheny-Singer Research Institute Anti-lymphocyte autoantibodies as diagnostic biomarkers

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
EP0267625A3 (en) * 1986-11-14 1989-08-30 Robert Aaron Levine Method of assaying biological fluid samples
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
AU641673B2 (en) 1989-06-29 1993-09-30 Medarex, Inc. Bispecific reagents for aids therapy
JPH06500011A (ja) 1990-06-29 1994-01-06 ラージ スケール バイオロジー コーポレイション 形質転換された微生物によるメラニンの製造
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
WO1992003918A1 (en) 1990-08-29 1992-03-19 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
WO1993008829A1 (en) 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
WO1994010571A1 (en) 1992-10-30 1994-05-11 T Cell Sciences, Inc. Measurement of total molecule in a sample and methods based thereon
DE60135732D1 (de) * 2000-02-28 2008-10-23 Univ British Columbia Topoisomerasehemmern zur behandlung von chirurgischen verklebungen
DK1432731T3 (da) 2001-09-10 2010-11-22 Univ Pittsburgh Diagnose og monitering af systemisk lupus erythematosus og af scleroderma
US20030158083A1 (en) * 2002-02-08 2003-08-21 The Procter & Gamble Company Method of effecting angiogenesis by modulating the function of a novel endothelia phosphatase
AU2004249155B2 (en) * 2003-06-13 2009-11-19 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Monitoring immunologic, hematologic and inflammatory diseases

Also Published As

Publication number Publication date
EP1756571A2 (en) 2007-02-28
WO2005108988A2 (en) 2005-11-17
JP2007532885A (ja) 2007-11-15
US20050282234A1 (en) 2005-12-22
DE602005023009D1 (de) 2010-09-30
US7361517B2 (en) 2008-04-22
EP1756571B1 (en) 2010-08-18
AU2005241415A1 (en) 2005-11-17
WO2005108988A3 (en) 2006-05-18
EP1756571A4 (en) 2008-05-07
ATE478335T1 (de) 2010-09-15
CA2561684A1 (en) 2005-11-17
EP1756571B8 (en) 2010-10-13
EP2216650A1 (en) 2010-08-11

Similar Documents

Publication Publication Date Title
DK1756571T3 (da) Fremgangsmåde i realtid til detektering af akut inflammatoriske tilstande
EP1745287A4 (en) DIAGNOSIS AND MONITORING OF INFLAMMATORY DISEASES BY MEASURING THE ADDITIONAL COMPONENTS OF LEUKOCYTES
ATE456055T1 (de) Diagnoseverfahren für erkrankungen im zusammenhang mit hirnschäden
WO2005103281A3 (en) Platelet biomarkers for the detection of disease
WO2009059150A3 (en) Biomarkers for fatty liver disease and methods using the same
WO2012018535A3 (en) Wellness panel
MX2009007368A (es) Deteccion, tratamiento y monitoreo de la inflamacion, por medio del receptor de disparo expresado en la celula 1 mieloide (trem-1).
IL172488A0 (en) Diagnostic methods for monitoring immunologic, hematologic and inflammatory diseases
WO2006059252A3 (en) Methods and fluorinated compositions for treating amyloid-related diseases
ATE447886T1 (de) Gerät zur überwachung der zerebralen perfusion
WO2006091893A3 (en) Mental alertness level determination
WO2009101059A3 (en) Methods of using cadherin 11 (cdh11) antagonists
ATE550658T1 (de) Verfahren für den nachweis oder die diagnose neurodegenerativer erkrankungen oder leiden
ATE524565T1 (de) Transkriptionsuntreue, nachweis und verwendungen davon
CA2575405A1 (en) Method for diagnosing liver fibrosis
WO2007050588A3 (en) Systems and methods for characterizing conditions of organs for transplantation
WO2007084397A3 (en) Processing of slpi by chymase
WO2007015113A3 (en) New protein isoforms of the pif-family and uses thereof
WO2007044622A8 (en) Use of mif and mif pathway agonists
WO2008117027A3 (en) Altered mitochondrial activity in diseases resulting from oxidative stress
WO2006116688A3 (en) Mif agonists and antagonists and therapeutic uses thereof
DK2196545T3 (da) Fremgangsmåder til forudsigelse af reaktionen hos patienter med dissemineret sclerose på interferonbehandling samt diagnosticering af dissemineret sclerose
WO2008008487A3 (en) Gene expression profiling for identification, monitoring and treatment of multiple sclerosis
JP2003513280A5 (da)
ATE509270T1 (de) Aus blutplättchen gewonnene mikropartikel als neue diagnosemarker für eine herz-kreislauf- erkrankung