DE60237529D1 - Diagnose und aufzeichnung von systemischem lupus erythematosus und von skleroderm - Google Patents

Diagnose und aufzeichnung von systemischem lupus erythematosus und von skleroderm

Info

Publication number
DE60237529D1
DE60237529D1 DE60237529T DE60237529T DE60237529D1 DE 60237529 D1 DE60237529 D1 DE 60237529D1 DE 60237529 T DE60237529 T DE 60237529T DE 60237529 T DE60237529 T DE 60237529T DE 60237529 D1 DE60237529 D1 DE 60237529D1
Authority
DE
Germany
Prior art keywords
diagnosis
lupus erythematosus
systemic lupus
sample
red blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60237529T
Other languages
English (en)
Inventor
Joseph M Ahearn
Susan M Manzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pittsburgh
Original Assignee
University of Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pittsburgh filed Critical University of Pittsburgh
Application granted granted Critical
Publication of DE60237529D1 publication Critical patent/DE60237529D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/104—Lupus erythematosus [SLE]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/973—Simultaneous determination of more than one analyte
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/821—Chemistry: analytical and immunological testing involving complement factors or complement systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Rehabilitation Therapy (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE60237529T 2001-09-10 2002-09-09 Diagnose und aufzeichnung von systemischem lupus erythematosus und von skleroderm Expired - Lifetime DE60237529D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31854101P 2001-09-10 2001-09-10
PCT/US2002/028910 WO2003022223A2 (en) 2001-09-10 2002-09-09 Diagnosis and monitoring of systemic lupus erythematosus and of scleroderma

Publications (1)

Publication Number Publication Date
DE60237529D1 true DE60237529D1 (de) 2010-10-14

Family

ID=23238613

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60237529T Expired - Lifetime DE60237529D1 (de) 2001-09-10 2002-09-09 Diagnose und aufzeichnung von systemischem lupus erythematosus und von skleroderm

Country Status (10)

Country Link
US (1) US7390631B2 (de)
EP (1) EP1432731B1 (de)
JP (2) JP4570872B2 (de)
AT (1) ATE479707T1 (de)
AU (2) AU2002323691C1 (de)
CA (1) CA2460189A1 (de)
DE (1) DE60237529D1 (de)
DK (1) DK1432731T3 (de)
ES (1) ES2350922T3 (de)
WO (1) WO2003022223A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE479707T1 (de) 2001-09-10 2010-09-15 Univ Pittsburgh Diagnose und aufzeichnung von systemischem lupus erythematosus und von skleroderm
JP4550051B2 (ja) 2003-04-16 2010-09-22 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 全身性エリテマトーデスの同定およびモニタリング
US8080382B2 (en) 2003-06-13 2011-12-20 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Monitoring immunologic, hematologic and inflammatory diseases
CA2561684A1 (en) 2004-04-09 2005-11-17 Joseph M. Ahearn Real time method of detecting acute inflammatory conditions
DE602005023725D1 (de) 2004-05-11 2010-11-04 Univ Pittsburgh Diagnose und überwachung von entzündlichen krankheiten mittels messung der zusätzlichen komponenten von leukozyten
US8524453B2 (en) * 2006-02-10 2013-09-03 The Brigham And Woman's Hospital, Inc. Lectin complement pathway assays and related compositions and methods
FR2899337B1 (fr) * 2006-03-31 2008-07-04 Univ Reims Champagne Ardenne Standard c4d / c4b pour cytometrie de flux quantitative du rejet humoral de transplantation.
CA2738952A1 (en) * 2008-10-16 2010-04-22 Cypress Bioscience, Inc. Method for diagnosis and monitoring of disease activity and response to treatment in systemic lupus erythematosus (sle) and other autoimmune diseases
WO2012109592A1 (en) 2011-02-11 2012-08-16 Exagen Diagnostics, Inc. Methods for diagnosing systemic lupus erythematosus
EP2954071B1 (de) 2013-02-08 2020-08-12 Allegheny-Singer Research Institute Zellgebundene komplementaktivierungsprodukte als diagnostische biomarker für prä-lupus
US9863946B2 (en) 2013-02-08 2018-01-09 Allegheny-Singer Research Institute Cell-bound complement activation products as diagnostic biomarkers for pre-lupus
CN105229470B (zh) 2013-03-15 2018-11-27 艾克斯肯诊断股份有限公司 用于治疗和诊断系统性红斑狼疮的方法
AU2016303499B2 (en) 2015-07-31 2020-07-02 Allegheny-Singer Research Institute Cell-bound complement activation product assays as companion diagnostics for antibody-based drugs
US12130288B2 (en) 2016-05-24 2024-10-29 Allegheny Singer Research Institute Methods and systems using C4 gene copy number and cell-bound complement activation products for identification of lupus and pre-lupus

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5426029A (en) * 1986-03-31 1995-06-20 T Cell Diagnostics, Inc. Therapeutic and diagnostic methods using leukocyte surface antigens
JPH02293665A (ja) * 1989-05-09 1990-12-04 Fujirebio Inc 腎疾患の検査方法
EP0666987A4 (de) 1992-10-30 1997-08-27 T Cell Diagnostics Inc Messung der gesamtzahl von molekülen in einer probe und darauf beruhende verfahren.
ATE479707T1 (de) 2001-09-10 2010-09-15 Univ Pittsburgh Diagnose und aufzeichnung von systemischem lupus erythematosus und von skleroderm
US8080382B2 (en) 2003-06-13 2011-12-20 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Monitoring immunologic, hematologic and inflammatory diseases

Also Published As

Publication number Publication date
ATE479707T1 (de) 2010-09-15
JP2010014720A (ja) 2010-01-21
EP1432731A4 (de) 2005-03-16
JP2005509146A (ja) 2005-04-07
EP1432731A2 (de) 2004-06-30
EP1432731B1 (de) 2010-09-01
DK1432731T3 (da) 2010-11-22
AU2002323691C1 (en) 2009-03-05
JP4570872B2 (ja) 2010-10-27
JP4906898B2 (ja) 2012-03-28
US20050037441A1 (en) 2005-02-17
AU2008202941A1 (en) 2008-07-24
CA2460189A1 (en) 2003-03-20
WO2003022223A2 (en) 2003-03-20
ES2350922T3 (es) 2011-01-28
US7390631B2 (en) 2008-06-24
WO2003022223A3 (en) 2003-07-24
AU2002323691B2 (en) 2008-04-03

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