ATE479707T1 - Diagnose und aufzeichnung von systemischem lupus erythematosus und von skleroderm - Google Patents

Diagnose und aufzeichnung von systemischem lupus erythematosus und von skleroderm

Info

Publication number
ATE479707T1
ATE479707T1 AT02757691T AT02757691T ATE479707T1 AT E479707 T1 ATE479707 T1 AT E479707T1 AT 02757691 T AT02757691 T AT 02757691T AT 02757691 T AT02757691 T AT 02757691T AT E479707 T1 ATE479707 T1 AT E479707T1
Authority
AT
Austria
Prior art keywords
diagnosis
lupus erythematosus
systemic lupus
sample
red blood
Prior art date
Application number
AT02757691T
Other languages
English (en)
Inventor
Joseph Ahearn
Susan Manzi
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Application granted granted Critical
Publication of ATE479707T1 publication Critical patent/ATE479707T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/104—Lupus erythematosus [SLE]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/973—Simultaneous determination of more than one analyte
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/821—Chemistry: analytical and immunological testing involving complement factors or complement systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Rehabilitation Therapy (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT02757691T 2001-09-10 2002-09-09 Diagnose und aufzeichnung von systemischem lupus erythematosus und von skleroderm ATE479707T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31854101P 2001-09-10 2001-09-10
PCT/US2002/028910 WO2003022223A2 (en) 2001-09-10 2002-09-09 Diagnosis and monitoring of systemic lupus erythematosus and of scleroderma

Publications (1)

Publication Number Publication Date
ATE479707T1 true ATE479707T1 (de) 2010-09-15

Family

ID=23238613

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02757691T ATE479707T1 (de) 2001-09-10 2002-09-09 Diagnose und aufzeichnung von systemischem lupus erythematosus und von skleroderm

Country Status (10)

Country Link
US (1) US7390631B2 (de)
EP (1) EP1432731B1 (de)
JP (2) JP4570872B2 (de)
AT (1) ATE479707T1 (de)
AU (2) AU2002323691C1 (de)
CA (1) CA2460189A1 (de)
DE (1) DE60237529D1 (de)
DK (1) DK1432731T3 (de)
ES (1) ES2350922T3 (de)
WO (1) WO2003022223A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003022223A2 (en) 2001-09-10 2003-03-20 University Of Pittsburgh Diagnosis and monitoring of systemic lupus erythematosus and of scleroderma
US7588905B2 (en) 2003-04-16 2009-09-15 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Identification and monitoring of systemic lupus erythematosus
AU2004249155B2 (en) 2003-06-13 2009-11-19 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Monitoring immunologic, hematologic and inflammatory diseases
CA2561684A1 (en) 2004-04-09 2005-11-17 Joseph M. Ahearn Real time method of detecting acute inflammatory conditions
US7585640B2 (en) * 2004-05-11 2009-09-08 University Of Pittsburgh Diagnosing and monitoring inflammatory diseases by measuring complement components on white blood cells
US8524453B2 (en) * 2006-02-10 2013-09-03 The Brigham And Woman's Hospital, Inc. Lectin complement pathway assays and related compositions and methods
FR2899337B1 (fr) * 2006-03-31 2008-07-04 Univ Reims Champagne Ardenne Standard c4d / c4b pour cytometrie de flux quantitative du rejet humoral de transplantation.
US20100233752A1 (en) * 2008-10-16 2010-09-16 Cypress Bioscience, Inc. Method for diagnosis and monitoring of disease activity and response to treatment in systemic lupus erythematosus (sle) and other autoimmune diseases
JP5990542B2 (ja) 2011-02-11 2016-09-14 エグザジェン ダイアグノスティクス インコーポレイテッドＥｘａｇｅｎ Ｄｉａｇｎｏｓｔｉｃｓ， Ｉｎｃ． 全身性エリテマトーデスのリスクスコアを算出する方法
US9863946B2 (en) 2013-02-08 2018-01-09 Allegheny-Singer Research Institute Cell-bound complement activation products as diagnostic biomarkers for pre-lupus
RU2019103573A (ru) 2013-02-08 2019-03-15 Аллегени-Сингер Рисерч Инститьют Клеточно-связанные продукты активации комплемента в качестве диагностических биомаркеров волчанки в доклинической стадии
EP2972365B1 (de) 2013-03-15 2019-11-20 Exagen Diagnostics, Inc. Verfahren zur behandlung und diagnostizierung von systemischem lupus erythematodes
CA2990722C (en) 2015-07-31 2022-07-05 Allegheny-Singer Research Institute Cell-bound complement activation product assays as companion diagnostics for antibody-based drugs
EP3465210B1 (de) 2016-05-24 2022-11-02 Allegheny-Singer Research Institute Verfahren und systeme mit c4-genkopienzahl und zellgebundenen komplementaktivierungsprodukten zur identifizierung von lupus und prä-lupus

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5426029A (en) * 1986-03-31 1995-06-20 T Cell Diagnostics, Inc. Therapeutic and diagnostic methods using leukocyte surface antigens
JPH02293665A (ja) * 1989-05-09 1990-12-04 Fujirebio Inc 腎疾患の検査方法
CA2148219C (en) 1992-10-30 1998-12-29 Charles W. Rittershaus Measurement of total molecule in a sample and methods based thereon
WO2003022223A2 (en) 2001-09-10 2003-03-20 University Of Pittsburgh Diagnosis and monitoring of systemic lupus erythematosus and of scleroderma
AU2004249155B2 (en) 2003-06-13 2009-11-19 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Monitoring immunologic, hematologic and inflammatory diseases

Also Published As

Publication number Publication date
DE60237529D1 (de) 2010-10-14
AU2002323691B2 (en) 2008-04-03
EP1432731A4 (de) 2005-03-16
WO2003022223A2 (en) 2003-03-20
DK1432731T3 (da) 2010-11-22
JP2005509146A (ja) 2005-04-07
WO2003022223A3 (en) 2003-07-24
JP4906898B2 (ja) 2012-03-28
US20050037441A1 (en) 2005-02-17
AU2002323691C1 (en) 2009-03-05
JP2010014720A (ja) 2010-01-21
EP1432731B1 (de) 2010-09-01
ES2350922T3 (es) 2011-01-28
JP4570872B2 (ja) 2010-10-27
EP1432731A2 (de) 2004-06-30
CA2460189A1 (en) 2003-03-20
AU2008202941A1 (en) 2008-07-24
US7390631B2 (en) 2008-06-24

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