ATE550658T1 - Verfahren für den nachweis oder die diagnose neurodegenerativer erkrankungen oder leiden - Google Patents
Verfahren für den nachweis oder die diagnose neurodegenerativer erkrankungen oder leidenInfo
- Publication number
- ATE550658T1 ATE550658T1 AT07749017T AT07749017T ATE550658T1 AT E550658 T1 ATE550658 T1 AT E550658T1 AT 07749017 T AT07749017 T AT 07749017T AT 07749017 T AT07749017 T AT 07749017T AT E550658 T1 ATE550658 T1 AT E550658T1
- Authority
- AT
- Austria
- Prior art keywords
- sample
- autoantibody
- level
- subject
- condition
- Prior art date
Links
- 208000015122 neurodegenerative disease Diseases 0.000 title abstract 7
- 238000001514 detection method Methods 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000004770 neurodegeneration Effects 0.000 abstract 6
- 210000001175 cerebrospinal fluid Anatomy 0.000 abstract 5
- 238000003556 assay Methods 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2835—Movement disorders, e.g. Parkinson, Huntington, Tourette
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/285—Demyelinating diseases; Multipel sclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Medical Treatment And Welfare Office Work (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/359,489 US7892751B2 (en) | 2003-06-09 | 2006-02-23 | Method of detecting or diagnosing of a neurodegenerative disease or condition |
| PCT/US2007/001582 WO2007106224A2 (en) | 2006-02-23 | 2007-01-22 | Method of detecting or diagnosing of a neurodegenerative disease or condition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE550658T1 true ATE550658T1 (de) | 2012-04-15 |
Family
ID=38509957
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07749017T ATE550658T1 (de) | 2006-02-23 | 2007-01-22 | Verfahren für den nachweis oder die diagnose neurodegenerativer erkrankungen oder leiden |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7892751B2 (de) |
| EP (1) | EP1989551B1 (de) |
| JP (1) | JP4880001B2 (de) |
| AT (1) | ATE550658T1 (de) |
| AU (1) | AU2007225434B2 (de) |
| BR (1) | BRPI0708138A2 (de) |
| CA (1) | CA2642869C (de) |
| MX (1) | MX2008010896A (de) |
| WO (1) | WO2007106224A2 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| US9557325B2 (en) * | 2003-06-09 | 2017-01-31 | Redox-Reactive Reagents Llc | Method of altering the binding specificity of proteins by oxidation-reduction reactions |
| US7892751B2 (en) * | 2003-06-09 | 2011-02-22 | Redox-Reactive Reagents Llc | Method of detecting or diagnosing of a neurodegenerative disease or condition |
| PT1976877E (pt) | 2005-11-30 | 2014-04-29 | Abbvie Inc | Anticorpos monoclonais contra proteína beta-amilóide e suas utilizações |
| BRPI0619249A2 (pt) | 2005-11-30 | 2011-09-20 | Abbott Lab | anticorpos anti-globulÈmeros-aß, frações que se ligam a antìgeno destes, hibridomas correspondentes, ácidos nucléicos, vetores, células hospedeiras, métodos de produzir os ditos anticorpos, composições compreendendo os ditos anticorpos, usos dos ditos anticorpos e métodos de usar os ditos anticorpos |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| EP2124952A2 (de) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Verfahren zur behandlung von amyloidosen |
| WO2010003602A1 (en) * | 2008-07-07 | 2010-01-14 | Athera Biotechnologies Ab | New therapeutic and diagnostic methods for alzheimer's disease |
| JP5249420B2 (ja) * | 2008-09-04 | 2013-07-31 | レドックス−リアクティブ リエイジェンツ リミテッド ライアビリティー カンパニー | アルツハイマー病の診断、モニタリングおよび／または病期診断のための、バイオマーカー、キットおよび方法 |
| EP2558494B1 (de) | 2010-04-15 | 2018-05-23 | AbbVie Inc. | Amyloid-beta-bindende proteine |
| US20120107841A1 (en) * | 2010-07-19 | 2012-05-03 | Mcintyre John A | Serum Diagnostic Method, Biomarker and Kit for Early Detection and Staging of Alzheimer's Disease |
| CN105348387B (zh) | 2010-08-14 | 2020-08-25 | Abbvie 公司 | β淀粉样蛋白结合蛋白 |
| ES2748117T3 (es) | 2015-04-22 | 2020-03-13 | Euroimmun Medizinische Labordiagnostika Ag | Diagnóstico de una nueva enfermedad autoinmune |
| US10405582B2 (en) | 2016-03-10 | 2019-09-10 | Pax Labs, Inc. | Vaporization device with lip sensing |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4703001A (en) * | 1985-10-23 | 1987-10-27 | Synbiotics, Corporation | Immunoassay for the detection of serum analytes using pH dependent chastropic acids |
| US4950612A (en) | 1987-12-16 | 1990-08-21 | Microgenics Corporation | Peroxy acid pretreatment in vitamin B12 assay |
| US5061790A (en) * | 1989-07-10 | 1991-10-29 | Molecular Diagnostics, Inc. | Oxidative denaturation of protein analytes |
| US5980954A (en) | 1992-02-07 | 1999-11-09 | Vasogen Ireland Limited | Treatment of autoimmune diseases |
| US6660267B1 (en) * | 1992-12-21 | 2003-12-09 | Promega Corporation | Prevention and treatment of sepsis |
| AU703814B2 (en) | 1995-12-04 | 1999-04-01 | Wyeth | Antioxidant |
| US5939394A (en) * | 1996-01-18 | 1999-08-17 | Fleming & Company | Methods and compositions for the prevention and treatment of immunological disorders, inflammatory diseases and infections |
| FR2794461B1 (fr) * | 1999-06-07 | 2004-01-23 | Lab Francais Du Fractionnement | Procede de preparation de nouvelles fractions d'ig humaines possedant une activite immunomodulatrice |
| FR2822238B1 (fr) * | 2001-03-16 | 2003-08-29 | Gemac | Methode et trousse pour le suivi des maladies neurodegeneratives |
| BRPI0411103B1 (pt) | 2003-06-09 | 2019-01-15 | A Mcintyre John | método, e, método de obtenção e isolamento de um autoanticorpo de um fluido biológico contendo anticorpo ou de um extrato de fluido biológico contendo anticorpo |
| US9557325B2 (en) * | 2003-06-09 | 2017-01-31 | Redox-Reactive Reagents Llc | Method of altering the binding specificity of proteins by oxidation-reduction reactions |
| US7892751B2 (en) * | 2003-06-09 | 2011-02-22 | Redox-Reactive Reagents Llc | Method of detecting or diagnosing of a neurodegenerative disease or condition |
-
2006
- 2006-02-23 US US11/359,489 patent/US7892751B2/en not_active Expired - Fee Related
-
2007
- 2007-01-22 AT AT07749017T patent/ATE550658T1/de active
- 2007-01-22 AU AU2007225434A patent/AU2007225434B2/en not_active Ceased
- 2007-01-22 CA CA2642869A patent/CA2642869C/en not_active Expired - Fee Related
- 2007-01-22 WO PCT/US2007/001582 patent/WO2007106224A2/en not_active Ceased
- 2007-01-22 MX MX2008010896A patent/MX2008010896A/es active IP Right Grant
- 2007-01-22 EP EP07749017A patent/EP1989551B1/de not_active Not-in-force
- 2007-01-22 JP JP2008556326A patent/JP4880001B2/ja not_active Expired - Fee Related
- 2007-01-22 BR BRPI0708138-3A patent/BRPI0708138A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007106224A2 (en) | 2007-09-20 |
| CA2642869C (en) | 2017-04-11 |
| WO2007106224B1 (en) | 2008-03-20 |
| JP4880001B2 (ja) | 2012-02-22 |
| BRPI0708138A2 (pt) | 2011-05-17 |
| MX2008010896A (es) | 2008-11-25 |
| AU2007225434A8 (en) | 2011-05-12 |
| EP1989551B1 (de) | 2012-03-21 |
| US20060141541A1 (en) | 2006-06-29 |
| EP1989551A4 (de) | 2010-01-06 |
| CA2642869A1 (en) | 2007-09-20 |
| AU2007225434B2 (en) | 2011-05-26 |
| AU2007225434A1 (en) | 2007-09-20 |
| JP2009527762A (ja) | 2009-07-30 |
| EP1989551A2 (de) | 2008-11-12 |
| US7892751B2 (en) | 2011-02-22 |
| WO2007106224A3 (en) | 2008-01-31 |
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