DK175597B1 - Anvendelse af en vævsplasminogenaktivator (t-PA) til fremstilling af et præparat til anvendelse til forebyggelse af fibrinaflejring eller adhærencedannelse eller -gendannelse, topiske præparater og dispenseringsindretninger til. - Google Patents

Anvendelse af en vævsplasminogenaktivator (t-PA) til fremstilling af et præparat til anvendelse til forebyggelse af fibrinaflejring eller adhærencedannelse eller -gendannelse, topiske præparater og dispenseringsindretninger til. Download PDF

Info

Publication number
DK175597B1
DK175597B1 DK198906753A DK675389A DK175597B1 DK 175597 B1 DK175597 B1 DK 175597B1 DK 198906753 A DK198906753 A DK 198906753A DK 675389 A DK675389 A DK 675389A DK 175597 B1 DK175597 B1 DK 175597B1
Authority
DK
Denmark
Prior art keywords
plasminogen activator
tissue plasminogen
formation
adherence
vehicle
Prior art date
Application number
DK198906753A
Other languages
Danish (da)
English (en)
Other versions
DK675389D0 (da
DK675389A (da
Inventor
Marjorie A Mohler
Tue H Nguyen
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DK675389D0 publication Critical patent/DK675389D0/da
Publication of DK675389A publication Critical patent/DK675389A/da
Application granted granted Critical
Publication of DK175597B1 publication Critical patent/DK175597B1/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49Urokinase; Tissue plasminogen activator
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK198906753A 1987-07-01 1989-12-29 Anvendelse af en vævsplasminogenaktivator (t-PA) til fremstilling af et præparat til anvendelse til forebyggelse af fibrinaflejring eller adhærencedannelse eller -gendannelse, topiske præparater og dispenseringsindretninger til. DK175597B1 (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US6887287A 1987-07-01 1987-07-01
US6887287 1987-07-01
US12531987A 1987-11-25 1987-11-25
US12531987 1987-11-25
US21089588A 1988-06-24 1988-06-24
US21089588 1988-06-24
US8802194 1988-06-30
PCT/US1988/002194 WO1989000049A1 (en) 1987-07-01 1988-06-30 Method and therapeutic compositions for the prevention of fibrin deposition or adhesions

Publications (3)

Publication Number Publication Date
DK675389D0 DK675389D0 (da) 1989-12-29
DK675389A DK675389A (da) 1990-02-28
DK175597B1 true DK175597B1 (da) 2004-12-13

Family

ID=27371438

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198906753A DK175597B1 (da) 1987-07-01 1989-12-29 Anvendelse af en vævsplasminogenaktivator (t-PA) til fremstilling af et præparat til anvendelse til forebyggelse af fibrinaflejring eller adhærencedannelse eller -gendannelse, topiske præparater og dispenseringsindretninger til.

Country Status (14)

Country Link
EP (1) EP0297860B1 (fi)
JP (1) JP2756131B2 (fi)
KR (1) KR0131330B1 (fi)
AU (1) AU621305B2 (fi)
DE (1) DE3883645T2 (fi)
DK (1) DK175597B1 (fi)
FI (1) FI103868B1 (fi)
IE (1) IE65658B1 (fi)
IL (2) IL86933A (fi)
NO (1) NO301748B1 (fi)
NZ (1) NZ225260A (fi)
PH (1) PH26527A (fi)
PT (1) PT87886B (fi)
WO (1) WO1989000049A1 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3741149A1 (de) * 1987-12-04 1989-06-15 Thomae Gmbh Dr K Zubereitungsformen zur verhinderung von adhaesionen von organen und organteilen
US5364622A (en) * 1987-12-04 1994-11-15 Dr. Karl Thomae Gmbh Methods for preventing adhesions to organs and parts of organs by application of tissue plasminogen activator and hydroxyethylcellulose hydrogel
CA1340994C (en) * 1989-09-21 2000-05-16 Rudolf Edgar Dr. Falk Treatment of conditions and disease
AU7073994A (en) * 1993-07-02 1995-01-24 Quest International B.V. Packaging of enzymes
US5869810A (en) * 1995-05-23 1999-02-09 Victor Reynolds Impedance-heated furnace
DE19529223A1 (de) * 1995-08-09 1997-02-13 Boehringer Mannheim Gmbh Verwendung von Plasminogenaktivatoren zum lokalen Knochenaufbau
US5837688A (en) * 1996-11-27 1998-11-17 Gelfand; Mathew I. Use of thrombolytic reagents for prevention of vascular disease
US7067485B2 (en) 1997-11-07 2006-06-27 Chiron Corporation IGF-I composition and its use
JP2001522813A (ja) * 1997-11-07 2001-11-20 カイロン コーポレイション 新規のigf−i組成物およびその使用
FR2918276B1 (fr) * 2007-07-02 2010-01-22 Anteis Sa "utilisation d'un gel de polysaccharide(s)naturel(s)pour la preparation d'une formulation injectable de traitement des degenerescences articulaires"
DE102014112212A1 (de) 2014-08-26 2016-03-03 Akesion Gmbh Rekombinante Fusionsproteine zur Vorbeugung oder Behandlung von Adhäsionen bei Geweben oder Organen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1229075B (it) * 1985-04-05 1991-07-17 Fidia Farmaceutici Medicamenti per uso topico, ottenuti tramite l'impiego dell'acido ialuronico
DE3500268A1 (de) * 1985-01-05 1986-07-10 Hoechst Ag, 6230 Frankfurt Praeparate mit verzoegerter wirkung, verfahren zu deren herstellung sowie entsprechende mittel zur human- bzw. veterinaermedizinischen anwendung
JPS6218742A (ja) * 1985-07-18 1987-01-27 Sony Corp ヒ−トシンクの製造方法
NZ217844A (en) * 1985-10-11 1989-10-27 Sumitomo Pharma A sustained release pharmaceutical composition containing silicone elastomer and an albumin
DE3682754D1 (de) * 1985-12-16 1992-01-16 Ethicon Inc Hemmung von post-chirurgischer adhaesionsbildung durch topische verabreichung von gewebeplasminogenaktivator.

Also Published As

Publication number Publication date
DK675389D0 (da) 1989-12-29
PH26527A (en) 1992-08-07
FI896359A0 (fi) 1989-12-29
NO301748B1 (no) 1997-12-08
WO1989000049A1 (en) 1989-01-12
DE3883645D1 (de) 1993-10-07
JP2756131B2 (ja) 1998-05-25
IE882023L (en) 1989-01-01
IE65658B1 (en) 1995-11-15
NO895338L (no) 1990-02-28
PT87886B (pt) 1993-09-30
IL102625A0 (en) 1993-01-14
KR890701124A (ko) 1989-12-19
AU621305B2 (en) 1992-03-12
FI103868B (fi) 1999-10-15
EP0297860B1 (en) 1993-09-01
NZ225260A (en) 1991-03-26
KR0131330B1 (ko) 1998-04-17
FI103868B1 (fi) 1999-10-15
NO895338D0 (no) 1989-12-29
JPH04502753A (ja) 1992-05-21
PT87886A (pt) 1989-06-30
EP0297860A1 (en) 1989-01-04
DK675389A (da) 1990-02-28
AU1998588A (en) 1989-01-30
DE3883645T2 (de) 1994-02-03
IL86933A (en) 1993-07-08

Similar Documents

Publication Publication Date Title
Liu et al. Crosslinked hyaluronan hydrogels containing mitomycin C reduce postoperative abdominal adhesions
US5604200A (en) Wound therapeutic mixture containing medical grade hyaluronic acid and tissue culture grade plasma-fibronectin in a delivery system that creates a moist environment which simulates in utero healing
US6037331A (en) Compositions for prevention of inflammation and adhesion formation uses thereof
US5866554A (en) Compositions for prevention of inflammation and adhesion formation and uses thereof
CA2577022A1 (en) Compositions and methods using hyaluronic acid and hyluronidase inhibitors
KR20080074107A (ko) 아미노산 및 히알루론산 나트륨에 기반한 안과용 약학적조성물
DK175597B1 (da) Anvendelse af en vævsplasminogenaktivator (t-PA) til fremstilling af et præparat til anvendelse til forebyggelse af fibrinaflejring eller adhærencedannelse eller -gendannelse, topiske præparater og dispenseringsindretninger til.
TW201313261A (zh) 防沾黏劑及使用該防沾黏劑之預防沾黏之方法
WO2000054762A2 (en) Use of cross linked polysaccharides for the inhibition of angiogenesis
JP2002511489A (ja) 液体媒体中の天然コラーゲンを滅菌する方法、得られた滅菌天然コラーゲン、それを含む組成物及びその使用
EP0318801B1 (de) Zubereitungsformen zur Verhinderung von Adhäsionen von Organen und Organteilen
JPH11506741A (ja) 術後癒着の防止及び腔内担体装置としてのヒドロキシエチルスターチの使用
Berkesoglu et al. Topical application of high-dose mesna prevents adhesion formation: an experimental animal study
CN113260370A (zh) 细胞重编程的方法
EP1001790B1 (en) Compositions for lubricating and separating tissues and biological membranes
US5589169A (en) Method and therapeutic compositions for the prevention of fibrin deposition or adhesions
EP1148886A2 (en) Use of a polyanionic polysaccharide solution for the prevention of abscess formation
Zhang et al. Evaluation of resorbable barrier for preventing surgical adhesions

Legal Events

Date Code Title Description
PUP Patent expired