DK174505B1 - Benzenderivater og fremgangsmåde til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne - Google Patents

Benzenderivater og fremgangsmåde til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne Download PDF

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Publication number
DK174505B1
DK174505B1 DK198906745A DK674589A DK174505B1 DK 174505 B1 DK174505 B1 DK 174505B1 DK 198906745 A DK198906745 A DK 198906745A DK 674589 A DK674589 A DK 674589A DK 174505 B1 DK174505 B1 DK 174505B1
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DK
Denmark
Prior art keywords
compound
cyclohexyl
formula
cis
chloro
Prior art date
Application number
DK198906745A
Other languages
Danish (da)
English (en)
Other versions
DK674589A (da
DK674589D0 (da
Inventor
Jean-Claude Breliere
Serge Lavastre
Raymond Paul
Pierre Casellas
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of DK674589D0 publication Critical patent/DK674589D0/da
Publication of DK674589A publication Critical patent/DK674589A/da
Application granted granted Critical
Publication of DK174505B1 publication Critical patent/DK174505B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C225/18—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings the carbon skeleton containing also rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
    • C07C211/35—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing only non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/38—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK198906745A 1988-12-30 1989-12-29 Benzenderivater og fremgangsmåde til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne DK174505B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8817538 1988-12-30
FR8817538A FR2641276B1 (fr) 1988-12-30 1988-12-30 Derives du benzene, leur preparation et les compositions pharmaceutiques en contenant

Publications (3)

Publication Number Publication Date
DK674589D0 DK674589D0 (da) 1989-12-29
DK674589A DK674589A (da) 1990-07-01
DK174505B1 true DK174505B1 (da) 2003-04-28

Family

ID=9373667

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198906745A DK174505B1 (da) 1988-12-30 1989-12-29 Benzenderivater og fremgangsmåde til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne

Country Status (22)

Country Link
US (2) US5354781A (es)
EP (1) EP0376850B1 (es)
JP (1) JP2588977B2 (es)
KR (1) KR0178366B1 (es)
AR (1) AR247548A1 (es)
AU (1) AU618439B2 (es)
CA (1) CA2006896C (es)
CZ (1) CZ419291A3 (es)
DE (1) DE68905171T2 (es)
DK (1) DK174505B1 (es)
ES (1) ES2055138T3 (es)
FI (1) FI98811C (es)
FR (1) FR2641276B1 (es)
GR (1) GR3007357T3 (es)
HK (1) HK1000541A1 (es)
HU (1) HU211155A9 (es)
IE (1) IE63689B1 (es)
IL (1) IL92889A (es)
NO (1) NO171847C (es)
NZ (1) NZ232010A (es)
PT (1) PT92761B (es)
ZA (1) ZA899955B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658821B1 (fr) * 1990-02-28 1994-09-16 Jouveinal Sa Nouvelles propanamines, leurs proprietes pharmacologiques et leur application a des fins therapeutiques, notamment antidiarrheuiques.
FR2742051B1 (fr) * 1995-12-06 1998-02-06 Synthelabo Utilisation de composes ayant une affinite pour le site de liaison du (3h)ifenprodil pour la fabrication de medicaments utiles dans la prevention et le traitement des neuropathies
FR2751645B1 (fr) * 1996-07-29 1998-12-24 Sanofi Sa Amines pour la fabrication de medicaments destines a empecher la proliferation de cellules tumorales
FR2794742B1 (fr) 1999-06-11 2005-06-03 Sanofi Synthelabo Nouveaux derives du benzene, un procede pour leur preparation et les compositions pharmaceutiques les contenant
FR2887454B1 (fr) * 2005-06-28 2009-06-05 Sanofi Aventis Sa Combinaisons antitumorales contenant des derives du taxane et des sigma ligands
DE102006031813B4 (de) 2006-07-07 2011-04-28 Christian-Albrechts-Universität Zu Kiel Verwendung basischer Acetophenone als Hemmstoffe von NO-Synthasen
EP3490556A4 (en) 2016-07-27 2020-04-15 Case Western Reserve University CONNECTIONS AND METHOD FOR PROMOTING MYELINIZATION
WO2019126702A1 (en) 2017-12-22 2019-06-27 Case Western Reserve University Compounds for promoting myelination
US20220024851A1 (en) 2018-12-03 2022-01-27 Convelo Therapeutics, Inc. Crystalline forms of multicyclic compounds and uses thereof
JP2023541960A (ja) 2020-09-17 2023-10-04 メレティオス セラピューティクス ウイルス感染を治療するための化合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1468761A (fr) * 1965-08-05 1967-02-10 Amines et esters carbamiques acétyléniques
AT316516B (de) * 1970-12-09 1974-07-10 Sumitomo Chemical Co Verfahren zur Herstellung von neuen Aminoalkoholen und von deren Säureadditionssalzen
GB1430063A (en) * 1972-03-24 1976-03-31 Wallis Separators Separator
GB1475314A (en) * 1973-11-02 1977-06-01 Cm Ind Phenyl-propylamine derivatives
US4104383A (en) * 1973-11-02 1978-08-01 C M Industries Derivatives of phenylpropenylamine
IT1113391B (it) * 1979-05-09 1986-01-20 Maggioni Farma Derivati fenilcicloesanici ad attivita' antidepressiva
DE3019497A1 (de) * 1980-05-22 1981-11-26 Bayer Ag, 5090 Leverkusen Aminopropiophenon-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
DE3541181A1 (de) * 1985-11-21 1987-05-27 Basf Ag Propylamine, verfahren zu ihrer herstellung und ihre verwendung als fungizide

Also Published As

Publication number Publication date
AU4737989A (en) 1990-07-05
IL92889A (en) 1994-02-27
NO171847C (no) 1993-05-12
GR3007357T3 (es) 1993-07-30
NO895220D0 (no) 1989-12-22
DK674589A (da) 1990-07-01
HK1000541A1 (en) 1998-04-03
FR2641276B1 (fr) 1991-07-12
ZA899955B (en) 1990-09-26
JPH032116A (ja) 1991-01-08
KR0178366B1 (ko) 1999-05-15
PT92761A (pt) 1990-06-29
IE894209L (en) 1990-06-30
EP0376850A1 (fr) 1990-07-04
NO895220L (no) 1990-07-02
US5449693A (en) 1995-09-12
ES2055138T3 (es) 1994-08-16
JP2588977B2 (ja) 1997-03-12
DE68905171T2 (de) 1993-06-17
CA2006896C (en) 1998-06-02
AR247548A1 (es) 1995-01-31
FI896342A0 (fi) 1989-12-29
NO171847B (no) 1993-02-01
EP0376850B1 (fr) 1993-03-03
FR2641276A1 (fr) 1990-07-06
HU211155A9 (en) 1995-10-30
CZ419291A3 (en) 1993-05-12
DE68905171D1 (de) 1993-04-08
US5354781A (en) 1994-10-11
NZ232010A (en) 1992-03-26
PT92761B (pt) 1996-01-31
CA2006896A1 (en) 1990-06-30
IL92889A0 (en) 1990-09-17
FI98811B (fi) 1997-05-15
IE63689B1 (en) 1995-05-31
DK674589D0 (da) 1989-12-29
KR900009580A (ko) 1990-07-04
AU618439B2 (en) 1991-12-19
FI98811C (fi) 1997-08-25

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