DK1740164T3 - Statine til behandling af okulær hypertension og glaukom - Google Patents
Statine til behandling af okulær hypertension og glaukomInfo
- Publication number
- DK1740164T3 DK1740164T3 DK05738648T DK05738648T DK1740164T3 DK 1740164 T3 DK1740164 T3 DK 1740164T3 DK 05738648 T DK05738648 T DK 05738648T DK 05738648 T DK05738648 T DK 05738648T DK 1740164 T3 DK1740164 T3 DK 1740164T3
- Authority
- DK
- Denmark
- Prior art keywords
- glaucoma
- statin
- treatment
- ocular hypertension
- statins
- Prior art date
Links
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 title abstract 5
- 208000010412 Glaucoma Diseases 0.000 title abstract 2
- 206010030043 Ocular hypertension Diseases 0.000 title 1
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 abstract 4
- 229940096701 plain lipid modifying drug hmg coa reductase inhibitors Drugs 0.000 abstract 2
- TUZYXOIXSAXUGO-UHFFFAOYSA-N Pravastatin Natural products C1=CC(C)C(CCC(O)CC(O)CC(O)=O)C2C(OC(=O)C(C)CC)CC(O)C=C21 TUZYXOIXSAXUGO-UHFFFAOYSA-N 0.000 abstract 1
- 208000017442 Retinal disease Diseases 0.000 abstract 1
- 206010038923 Retinopathy Diseases 0.000 abstract 1
- 230000004410 intraocular pressure Effects 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 229960002965 pravastatin Drugs 0.000 abstract 1
- TUZYXOIXSAXUGO-PZAWKZKUSA-N pravastatin Chemical compound C1=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@H]2[C@@H](OC(=O)[C@@H](C)CC)C[C@H](O)C=C21 TUZYXOIXSAXUGO-PZAWKZKUSA-N 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 210000001585 trabecular meshwork Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56546904P | 2004-04-26 | 2004-04-26 | |
| PCT/US2005/014255 WO2005105069A1 (en) | 2004-04-26 | 2005-04-25 | Statins for the treatment of ocular hypertension and glaucoma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1740164T3 true DK1740164T3 (da) | 2008-11-10 |
Family
ID=34966865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05738648T DK1740164T3 (da) | 2004-04-26 | 2005-04-25 | Statine til behandling af okulær hypertension og glaukom |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20050239871A1 (enExample) |
| EP (1) | EP1740164B1 (enExample) |
| JP (1) | JP2007534699A (enExample) |
| KR (2) | KR20110091600A (enExample) |
| CN (1) | CN1946384B (enExample) |
| AT (1) | ATE404189T1 (enExample) |
| AU (1) | AU2005237543B2 (enExample) |
| BR (1) | BRPI0510245A (enExample) |
| CA (1) | CA2560167A1 (enExample) |
| CY (1) | CY1108490T1 (enExample) |
| DE (1) | DE602005008935D1 (enExample) |
| DK (1) | DK1740164T3 (enExample) |
| ES (1) | ES2311986T3 (enExample) |
| MX (1) | MXPA06012225A (enExample) |
| PL (1) | PL1740164T3 (enExample) |
| PT (1) | PT1740164E (enExample) |
| SI (1) | SI1740164T1 (enExample) |
| WO (1) | WO2005105069A1 (enExample) |
| ZA (1) | ZA200607988B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005053683A1 (en) * | 2003-11-26 | 2005-06-16 | Duke University | A method of preventing or treating glaucoma |
| WO2007070866A2 (en) * | 2005-12-16 | 2007-06-21 | Alcon, Inc. | Control of intraocular pressure using alk5 modulation agents |
| PL2018153T3 (pl) | 2006-04-26 | 2012-09-28 | Rosemont Pharmaceuticals Ltd | Ciekłe kompozycje doustne |
| US20090202524A1 (en) * | 2007-10-31 | 2009-08-13 | Alcon Research, Ltd. | Pai-1 expression and activity inhibitors for the treatment of ocular disorders |
| ES2330184B1 (es) * | 2008-06-03 | 2010-07-05 | Neuron Biopharma, S.A. | Uso de estatinas como anticonvulsivantes, antiepilepticos y neuroprotectores. |
| US20110293549A1 (en) | 2009-02-03 | 2011-12-01 | Athena Cosmetics, Inc. | Composition, method and kit for enhancing hair |
| US8299079B2 (en) | 2009-05-22 | 2012-10-30 | Kaufman Herbert E | Preparations and methods for ameliorating or reducing presbyopia |
| CN102093984B (zh) * | 2010-11-23 | 2012-07-04 | 清华大学 | 一种杂合酶P450sca2-BMR及其编码基因与应用 |
| CN104902892A (zh) | 2012-02-02 | 2015-09-09 | 悉尼大学 | 泪液膜稳定性的改进 |
| GB201611782D0 (en) * | 2016-07-06 | 2016-08-17 | Optibiotix Ltd | Composition |
| US10696638B2 (en) | 2017-12-26 | 2020-06-30 | Industrial Technology Research Institute | Compounds for inhibiting AGC kinase and pharmaceutical compositions comprising the same |
| WO2025147589A1 (en) * | 2024-01-05 | 2025-07-10 | Osanni Bio, Inc. | Implants, compositions, and methods for treating retinal diseases and disorders |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2534580A1 (fr) * | 1982-10-13 | 1984-04-20 | Synthelabo | Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent |
| FR2585708B1 (fr) * | 1985-07-31 | 1989-07-07 | Sanofi Sa | Derives aminoalcools peptidiques inhibiteurs de la resine et des proteases acides, leur procede de preparation et leur application en therapeutique |
| US5151444B1 (en) * | 1987-09-18 | 1999-07-06 | R Tech Ueno Ltd | Ocular hypotensive agents |
| US5296504A (en) * | 1988-09-06 | 1994-03-22 | Kabi Pharmacia | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
| ES2213504T1 (es) * | 1988-09-06 | 2004-09-01 | Pfizer Health Ab | Derivados de prostaglandina para el tratamiento del glaucoma o hipertension ocular. |
| FR2647675B1 (fr) * | 1989-06-05 | 1994-05-20 | Sanofi | Utilisation d'un derive de la statine dans le traitement des affections oculaires |
| JPH04243835A (ja) * | 1990-08-29 | 1992-08-31 | Pfizer Inc | 高眼圧症又は緑内障治療用薬剤組成物及び治療方法 |
| US5352708A (en) * | 1992-09-21 | 1994-10-04 | Allergan, Inc. | Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
| US5510383A (en) * | 1993-08-03 | 1996-04-23 | Alcon Laboratories, Inc. | Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension |
| US5599535A (en) * | 1995-06-07 | 1997-02-04 | Regents Of The University Of California | Methods for the cyto-protection of the trabecular meshwork |
| US6586425B2 (en) * | 1996-02-21 | 2003-07-01 | Wisconsin Alumni Research Foundation | Cytoskeletal active agents for glaucoma therapy |
| US6569461B1 (en) * | 1999-03-08 | 2003-05-27 | Merck & Co., Inc. | Dihydroxy open-acid and salts of HMG-CoA reductase inhibitors |
| EP1322306A2 (en) * | 2000-09-19 | 2003-07-02 | NovImmune S.A. | Use of statins (hmg-coa reductase inhibitors) for the preparation of medicament as a novel type of immunomodulator, immunosuppressor and anti-inflammatory agent |
| US20030065020A1 (en) * | 2001-07-13 | 2003-04-03 | Catharine Gale | Treatment of macular degeneration |
| US20030195167A1 (en) * | 2002-04-15 | 2003-10-16 | Kowa Co., Ltd. | PTX3-gene expression inhibitor |
| JP2004149480A (ja) * | 2002-10-31 | 2004-05-27 | Saisentan Igaku Kenkyusho:Kk | 経口又は経皮投与用の眼科疾患治療剤 |
| US20040248972A1 (en) * | 2003-05-16 | 2004-12-09 | Ambit Biosciences Corporation | Compounds and uses thereof |
| CA2523808A1 (en) * | 2003-05-16 | 2004-12-23 | Ambit Biosciences Corporation | Pyrrole compounds and uses thereof |
| US20060241122A1 (en) * | 2003-05-30 | 2006-10-26 | Lee Margaret S | Combination therapy for the treatment of neoplasms |
| WO2005053683A1 (en) * | 2003-11-26 | 2005-06-16 | Duke University | A method of preventing or treating glaucoma |
| US20090202524A1 (en) * | 2007-10-31 | 2009-08-13 | Alcon Research, Ltd. | Pai-1 expression and activity inhibitors for the treatment of ocular disorders |
-
2005
- 2005-04-25 AU AU2005237543A patent/AU2005237543B2/en not_active Ceased
- 2005-04-25 SI SI200530460T patent/SI1740164T1/sl unknown
- 2005-04-25 ES ES05738648T patent/ES2311986T3/es not_active Expired - Lifetime
- 2005-04-25 CN CN2005800130061A patent/CN1946384B/zh not_active Expired - Fee Related
- 2005-04-25 WO PCT/US2005/014255 patent/WO2005105069A1/en not_active Ceased
- 2005-04-25 BR BRPI0510245-6A patent/BRPI0510245A/pt not_active IP Right Cessation
- 2005-04-25 KR KR1020117018000A patent/KR20110091600A/ko not_active Withdrawn
- 2005-04-25 MX MXPA06012225A patent/MXPA06012225A/es active IP Right Grant
- 2005-04-25 ZA ZA200607988A patent/ZA200607988B/xx unknown
- 2005-04-25 JP JP2007509736A patent/JP2007534699A/ja active Pending
- 2005-04-25 DK DK05738648T patent/DK1740164T3/da active
- 2005-04-25 PT PT05738648T patent/PT1740164E/pt unknown
- 2005-04-25 AT AT05738648T patent/ATE404189T1/de active
- 2005-04-25 PL PL05738648T patent/PL1740164T3/pl unknown
- 2005-04-25 EP EP05738648A patent/EP1740164B1/en not_active Expired - Lifetime
- 2005-04-25 US US11/114,512 patent/US20050239871A1/en not_active Abandoned
- 2005-04-25 DE DE602005008935T patent/DE602005008935D1/de not_active Expired - Lifetime
- 2005-04-25 CA CA002560167A patent/CA2560167A1/en not_active Abandoned
-
2006
- 2006-11-15 KR KR1020067023958A patent/KR101071192B1/ko not_active Expired - Fee Related
-
2008
- 2008-11-07 CY CY20081101271T patent/CY1108490T1/el unknown
-
2010
- 2010-11-08 US US12/941,639 patent/US20110098314A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005237543A1 (en) | 2005-11-10 |
| US20050239871A1 (en) | 2005-10-27 |
| SI1740164T1 (sl) | 2009-02-28 |
| EP1740164A1 (en) | 2007-01-10 |
| PT1740164E (pt) | 2008-10-21 |
| KR20110091600A (ko) | 2011-08-11 |
| CY1108490T1 (el) | 2014-04-09 |
| ATE404189T1 (de) | 2008-08-15 |
| KR20070007932A (ko) | 2007-01-16 |
| CN1946384A (zh) | 2007-04-11 |
| CN1946384B (zh) | 2011-04-20 |
| HK1102913A1 (en) | 2007-12-07 |
| WO2005105069A1 (en) | 2005-11-10 |
| CA2560167A1 (en) | 2005-11-10 |
| US20110098314A1 (en) | 2011-04-28 |
| ZA200607988B (en) | 2007-12-27 |
| PL1740164T3 (pl) | 2009-01-30 |
| JP2007534699A (ja) | 2007-11-29 |
| ES2311986T3 (es) | 2009-02-16 |
| BRPI0510245A (pt) | 2007-10-23 |
| DE602005008935D1 (de) | 2008-09-25 |
| KR101071192B1 (ko) | 2011-10-10 |
| AU2005237543B2 (en) | 2011-02-10 |
| EP1740164B1 (en) | 2008-08-13 |
| MXPA06012225A (es) | 2007-01-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1108490T1 (el) | Στατινες για την αντιμετωπιση της οφθαλμικης υπερτασης και του γλαυκωματος | |
| WO2006066103A3 (en) | Ophthalmic implant for treatment of glaucoma | |
| WO2004103960A3 (en) | Compounds and uses thereof | |
| WO2005002520A3 (en) | Ophthalmic compositions for treating ocular hypertension | |
| WO2007076360A8 (en) | (indazol-5-yl)-pyrazines and (1,3-dihydro-indol-2-one)- pyrazines for treating rho kinase-mediated diseases and conditions | |
| WO2003092584A3 (en) | Agents which regulate, inhibit, or modulate the activity and/or expression of connective tissue growth factor (ctgf) as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies | |
| NO20072187L (no) | Preventivt eller terapeutisk middel for glaucom | |
| ATE359794T1 (de) | 3, 7 thiaprostansäurederivate als mittel zur verminderung des augeninnendruckes | |
| WO2003047513A3 (en) | Method for treating ocular hypertension | |
| TW200501949A (en) | Ophthalmic compositions for treating ocular hypertension | |
| WO2005020917A3 (en) | Ophthalmic compositions for treating ocular hypertension | |
| DE60234919D1 (de) | 3, 7 oder 3 und 7 thia- oder oxaprostansäure derivate als mittel zur senkung des augeninnendrucks | |
| EP1488808A4 (en) | Remedies for glomerular diseases | |
| WO2004043354A3 (en) | Ophthalmic compositions for treating ocular hypertension | |
| WO2002062293A3 (en) | Coumarin compounds as microtubule stabilizing agents and therapeutic uses thereof | |
| WO2007127711A3 (en) | Abnormal cannabidiols as agents for lowering intraocular pressure | |
| ATE444299T1 (de) | Neue boronatester | |
| ATE409491T1 (de) | Orhthalmologische zusammenstellungen zur behandlung von ocularer hypertension | |
| MXPA04006029A (es) | Derivados novedosos de benzofuranimidazolina y benzodifuranimidazolina y su uso para el tratamiento de glaucoma. | |
| MXPA04001255A (es) | Uso de compuesto para el tratamiento de condiciones que resultan de lesion al nervio corneo despues de lasik y otras cirugias oculares o trauma. | |
| WO2006020003A3 (en) | Ophthalmic compositions for treating ocular hypertension | |
| WO2002060339A3 (en) | Ophthalmic compositions for treating ocular hypertension | |
| WO2021142333A3 (en) | Inhibitors of microbially induced amyloid | |
| WO2003077845A3 (en) | Compositions and methods for treating glaucoma and ocular hypertension | |
| WO2004087051A3 (en) | Ophthalmic compositions for treating ocular hypertension |