AU2005237543B2 - Statins for the treatment of ocular hypertension and glaucoma - Google Patents

Statins for the treatment of ocular hypertension and glaucoma Download PDF

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Publication number
AU2005237543B2
AU2005237543B2 AU2005237543A AU2005237543A AU2005237543B2 AU 2005237543 B2 AU2005237543 B2 AU 2005237543B2 AU 2005237543 A AU2005237543 A AU 2005237543A AU 2005237543 A AU2005237543 A AU 2005237543A AU 2005237543 B2 AU2005237543 B2 AU 2005237543B2
Authority
AU
Australia
Prior art keywords
statin
person
composition
combination
medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005237543A
Other languages
English (en)
Other versions
AU2005237543A1 (en
Inventor
Debra L. Fleenor
Mark R. Hellberg
Iok-Hou Pang
Allan Shepard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Inc
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of AU2005237543A1 publication Critical patent/AU2005237543A1/en
Application granted granted Critical
Publication of AU2005237543B2 publication Critical patent/AU2005237543B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225Polycarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
AU2005237543A 2004-04-26 2005-04-25 Statins for the treatment of ocular hypertension and glaucoma Ceased AU2005237543B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56546904P 2004-04-26 2004-04-26
US60/565,469 2004-04-26
PCT/US2005/014255 WO2005105069A1 (en) 2004-04-26 2005-04-25 Statins for the treatment of ocular hypertension and glaucoma

Publications (2)

Publication Number Publication Date
AU2005237543A1 AU2005237543A1 (en) 2005-11-10
AU2005237543B2 true AU2005237543B2 (en) 2011-02-10

Family

ID=34966865

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005237543A Ceased AU2005237543B2 (en) 2004-04-26 2005-04-25 Statins for the treatment of ocular hypertension and glaucoma

Country Status (19)

Country Link
US (2) US20050239871A1 (enExample)
EP (1) EP1740164B1 (enExample)
JP (1) JP2007534699A (enExample)
KR (2) KR20110091600A (enExample)
CN (1) CN1946384B (enExample)
AT (1) ATE404189T1 (enExample)
AU (1) AU2005237543B2 (enExample)
BR (1) BRPI0510245A (enExample)
CA (1) CA2560167A1 (enExample)
CY (1) CY1108490T1 (enExample)
DE (1) DE602005008935D1 (enExample)
DK (1) DK1740164T3 (enExample)
ES (1) ES2311986T3 (enExample)
MX (1) MXPA06012225A (enExample)
PL (1) PL1740164T3 (enExample)
PT (1) PT1740164E (enExample)
SI (1) SI1740164T1 (enExample)
WO (1) WO2005105069A1 (enExample)
ZA (1) ZA200607988B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005053683A1 (en) * 2003-11-26 2005-06-16 Duke University A method of preventing or treating glaucoma
WO2007070866A2 (en) * 2005-12-16 2007-06-21 Alcon, Inc. Control of intraocular pressure using alk5 modulation agents
PL2018153T3 (pl) 2006-04-26 2012-09-28 Rosemont Pharmaceuticals Ltd Ciekłe kompozycje doustne
US20090202524A1 (en) * 2007-10-31 2009-08-13 Alcon Research, Ltd. Pai-1 expression and activity inhibitors for the treatment of ocular disorders
ES2330184B1 (es) * 2008-06-03 2010-07-05 Neuron Biopharma, S.A. Uso de estatinas como anticonvulsivantes, antiepilepticos y neuroprotectores.
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair
US8299079B2 (en) 2009-05-22 2012-10-30 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
CN102093984B (zh) * 2010-11-23 2012-07-04 清华大学 一种杂合酶P450sca2-BMR及其编码基因与应用
CN104902892A (zh) 2012-02-02 2015-09-09 悉尼大学 泪液膜稳定性的改进
GB201611782D0 (en) * 2016-07-06 2016-08-17 Optibiotix Ltd Composition
US10696638B2 (en) 2017-12-26 2020-06-30 Industrial Technology Research Institute Compounds for inhibiting AGC kinase and pharmaceutical compositions comprising the same
WO2025147589A1 (en) * 2024-01-05 2025-07-10 Osanni Bio, Inc. Implants, compositions, and methods for treating retinal diseases and disorders

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0473337A2 (en) * 1990-08-29 1992-03-04 Pfizer Inc. Nor-statine and nor-cyclostatine polypeptides in the treatment of ocular hypertension and glaucoma
US5134124A (en) * 1989-06-05 1992-07-28 Sanofi Use of a statin derivative in the treatment of eye complaints
US20020159973A1 (en) * 2000-09-19 2002-10-31 Francois Mach Treatment of psoriasis with statins (HMG-Coa reductase inhibitors)
US20030065020A1 (en) * 2001-07-13 2003-04-03 Catharine Gale Treatment of macular degeneration
WO2003086380A1 (en) * 2002-04-15 2003-10-23 Kowa Co., Ltd. Ptx3 gene expression suppressing method
WO2004103960A2 (en) * 2003-05-16 2004-12-02 Ambit Biosciences Corporation Compounds and uses thereof
WO2005000208A2 (en) * 2003-05-30 2005-01-06 Combinatorx, Inc. Combination therapy for the treatment of neoplasms
WO2005053683A1 (en) * 2003-11-26 2005-06-16 Duke University A method of preventing or treating glaucoma

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534580A1 (fr) * 1982-10-13 1984-04-20 Synthelabo Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent
FR2585708B1 (fr) * 1985-07-31 1989-07-07 Sanofi Sa Derives aminoalcools peptidiques inhibiteurs de la resine et des proteases acides, leur procede de preparation et leur application en therapeutique
US5151444B1 (en) * 1987-09-18 1999-07-06 R Tech Ueno Ltd Ocular hypotensive agents
US5296504A (en) * 1988-09-06 1994-03-22 Kabi Pharmacia Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
ES2213504T1 (es) * 1988-09-06 2004-09-01 Pfizer Health Ab Derivados de prostaglandina para el tratamiento del glaucoma o hipertension ocular.
US5352708A (en) * 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5510383A (en) * 1993-08-03 1996-04-23 Alcon Laboratories, Inc. Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
US5599535A (en) * 1995-06-07 1997-02-04 Regents Of The University Of California Methods for the cyto-protection of the trabecular meshwork
US6586425B2 (en) * 1996-02-21 2003-07-01 Wisconsin Alumni Research Foundation Cytoskeletal active agents for glaucoma therapy
US6569461B1 (en) * 1999-03-08 2003-05-27 Merck & Co., Inc. Dihydroxy open-acid and salts of HMG-CoA reductase inhibitors
JP2004149480A (ja) * 2002-10-31 2004-05-27 Saisentan Igaku Kenkyusho:Kk 経口又は経皮投与用の眼科疾患治療剤
US20040248972A1 (en) * 2003-05-16 2004-12-09 Ambit Biosciences Corporation Compounds and uses thereof
US20090202524A1 (en) * 2007-10-31 2009-08-13 Alcon Research, Ltd. Pai-1 expression and activity inhibitors for the treatment of ocular disorders

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5134124A (en) * 1989-06-05 1992-07-28 Sanofi Use of a statin derivative in the treatment of eye complaints
EP0473337A2 (en) * 1990-08-29 1992-03-04 Pfizer Inc. Nor-statine and nor-cyclostatine polypeptides in the treatment of ocular hypertension and glaucoma
US20020159973A1 (en) * 2000-09-19 2002-10-31 Francois Mach Treatment of psoriasis with statins (HMG-Coa reductase inhibitors)
US20030065020A1 (en) * 2001-07-13 2003-04-03 Catharine Gale Treatment of macular degeneration
WO2003086380A1 (en) * 2002-04-15 2003-10-23 Kowa Co., Ltd. Ptx3 gene expression suppressing method
WO2004103960A2 (en) * 2003-05-16 2004-12-02 Ambit Biosciences Corporation Compounds and uses thereof
WO2005000208A2 (en) * 2003-05-30 2005-01-06 Combinatorx, Inc. Combination therapy for the treatment of neoplasms
WO2005053683A1 (en) * 2003-11-26 2005-06-16 Duke University A method of preventing or treating glaucoma

Also Published As

Publication number Publication date
AU2005237543A1 (en) 2005-11-10
US20050239871A1 (en) 2005-10-27
SI1740164T1 (sl) 2009-02-28
EP1740164A1 (en) 2007-01-10
PT1740164E (pt) 2008-10-21
KR20110091600A (ko) 2011-08-11
CY1108490T1 (el) 2014-04-09
ATE404189T1 (de) 2008-08-15
KR20070007932A (ko) 2007-01-16
CN1946384A (zh) 2007-04-11
CN1946384B (zh) 2011-04-20
HK1102913A1 (en) 2007-12-07
WO2005105069A1 (en) 2005-11-10
CA2560167A1 (en) 2005-11-10
US20110098314A1 (en) 2011-04-28
ZA200607988B (en) 2007-12-27
DK1740164T3 (da) 2008-11-10
PL1740164T3 (pl) 2009-01-30
JP2007534699A (ja) 2007-11-29
ES2311986T3 (es) 2009-02-16
BRPI0510245A (pt) 2007-10-23
DE602005008935D1 (de) 2008-09-25
KR101071192B1 (ko) 2011-10-10
EP1740164B1 (en) 2008-08-13
MXPA06012225A (es) 2007-01-31

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired