DK172710B1 - Fremgangsmåde til fremstilling af en fast form til oral anvendelse baseret på nifedipin med reguleret frigørelse af aktivst - Google Patents
Fremgangsmåde til fremstilling af en fast form til oral anvendelse baseret på nifedipin med reguleret frigørelse af aktivst Download PDFInfo
- Publication number
- DK172710B1 DK172710B1 DK198602221A DK222186A DK172710B1 DK 172710 B1 DK172710 B1 DK 172710B1 DK 198602221 A DK198602221 A DK 198602221A DK 222186 A DK222186 A DK 222186A DK 172710 B1 DK172710 B1 DK 172710B1
- Authority
- DK
- Denmark
- Prior art keywords
- nifedipine
- controlled release
- active substance
- binder
- low molecular
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Cosmetics (AREA)
- Silver Salt Photography Or Processing Solution Therefor (AREA)
- Electroplating And Plating Baths Therefor (AREA)
- Surgical Instruments (AREA)
- Steering Control In Accordance With Driving Conditions (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22678/84A IT1178511B (it) | 1984-09-14 | 1984-09-14 | Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio |
IT2267884 | 1984-09-14 | ||
EP8500481 | 1985-09-04 | ||
PCT/EP1985/000481 WO1986001717A1 (fr) | 1984-09-14 | 1985-09-04 | Preparation de nifedipine a liberation controlee |
Publications (3)
Publication Number | Publication Date |
---|---|
DK222186D0 DK222186D0 (da) | 1986-05-13 |
DK222186A DK222186A (da) | 1986-05-13 |
DK172710B1 true DK172710B1 (da) | 1999-06-07 |
Family
ID=11199169
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK198602221A DK172710B1 (da) | 1984-09-14 | 1986-05-13 | Fremgangsmåde til fremstilling af en fast form til oral anvendelse baseret på nifedipin med reguleret frigørelse af aktivst |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0226588B1 (fr) |
JP (1) | JPS62500660A (fr) |
AT (1) | ATE61733T1 (fr) |
AU (1) | AU588258B2 (fr) |
CA (1) | CA1253079A (fr) |
DE (1) | DE3582251D1 (fr) |
DK (1) | DK172710B1 (fr) |
ES (1) | ES8702137A1 (fr) |
FI (1) | FI87991C (fr) |
IE (1) | IE58490B1 (fr) |
IT (1) | IT1178511B (fr) |
NO (1) | NO171887C (fr) |
PT (1) | PT81113B (fr) |
WO (1) | WO1986001717A1 (fr) |
YU (1) | YU45988B (fr) |
ZA (1) | ZA856862B (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1187751B (it) * | 1985-10-15 | 1987-12-23 | Eurand Spa | Procedimento per la preparazione di formulazioni solidi di nifedipina ad elevata biodisponibilita' e ad effetto prolungato e formulazioni cosi' ottenute |
SE8601624D0 (sv) * | 1986-04-11 | 1986-04-11 | Haessle Ab | New pharmaceutical preparations |
DK173505B1 (da) * | 1987-02-20 | 2001-01-15 | Pharmatec Internat S R L | Fremgangsmåde til fremstilling af en diltiazempellet med langsom afgivelse og anvendelse af således fremstillede pelleter t |
GB8722306D0 (en) * | 1987-09-22 | 1987-10-28 | Aps Research Ltd | Sustained-release formulation |
GB8903328D0 (en) * | 1989-02-14 | 1989-04-05 | Ethical Pharma Ltd | Nifedipine-containing pharmaceutical compositions and process for the preparation thereof |
HU203041B (en) * | 1989-03-14 | 1991-05-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin |
US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
US5122384A (en) * | 1989-05-05 | 1992-06-16 | Kv Pharmaceutical Company | Oral once-per-day organic nitrate formulation which does not induce tolerance |
GB9200607D0 (en) * | 1992-01-13 | 1992-03-11 | Ethical Pharma Ltd | Pharmaceutical compositions containing nifedipine and process for the preparation thereof |
WO1994005262A1 (fr) * | 1992-09-10 | 1994-03-17 | F.H. Faulding & Co. Limited | Composition sous forme de matrice a liberation prolongee |
US6077533A (en) * | 1994-05-25 | 2000-06-20 | Purdue Pharma L.P. | Powder-layered oral dosage forms |
US7060293B1 (en) | 1994-05-25 | 2006-06-13 | Purdue Pharma | Powder-layered oral dosage forms |
WO1996020707A1 (fr) * | 1994-12-29 | 1996-07-11 | Dr. Rentschler Arzneimittel Gmbh & Co. | Preparations pharmaceutiques contenant de la nifedipine et procedes permettant de les preparer |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2453642A1 (fr) * | 1979-04-12 | 1980-11-07 | Sanofi Sa | Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotoxine |
DE3033919A1 (de) * | 1980-09-09 | 1982-04-22 | Bayer Ag, 5090 Leverkusen | Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung |
DE3433239A1 (de) * | 1984-09-11 | 1986-03-20 | Bayer Ag, 5090 Leverkusen | Feste arzneizubereitung enthaltend nitrendipin und verfahren zu ihrer herstellung |
IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
-
1984
- 1984-09-14 IT IT22678/84A patent/IT1178511B/it active
-
1985
- 1985-09-04 DE DE8585904808T patent/DE3582251D1/de not_active Expired - Lifetime
- 1985-09-04 AU AU49594/85A patent/AU588258B2/en not_active Ceased
- 1985-09-04 AT AT85904808T patent/ATE61733T1/de not_active IP Right Cessation
- 1985-09-04 EP EP85904808A patent/EP0226588B1/fr not_active Expired - Lifetime
- 1985-09-04 JP JP60504334A patent/JPS62500660A/ja active Granted
- 1985-09-04 WO PCT/EP1985/000481 patent/WO1986001717A1/fr active IP Right Grant
- 1985-09-06 ZA ZA856862A patent/ZA856862B/xx unknown
- 1985-09-12 CA CA000490628A patent/CA1253079A/fr not_active Expired
- 1985-09-12 PT PT81113A patent/PT81113B/pt unknown
- 1985-09-13 IE IE226285A patent/IE58490B1/en not_active IP Right Cessation
- 1985-09-13 YU YU143985A patent/YU45988B/sh unknown
- 1985-09-13 ES ES547707A patent/ES8702137A1/es not_active Expired
-
1986
- 1986-05-07 NO NO86861845A patent/NO171887C/no not_active IP Right Cessation
- 1986-05-13 DK DK198602221A patent/DK172710B1/da not_active IP Right Cessation
-
1987
- 1987-03-13 FI FI871116A patent/FI87991C/fi not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ZA856862B (en) | 1986-05-28 |
IE852262L (en) | 1986-03-14 |
NO861845L (no) | 1986-05-07 |
ES547707A0 (es) | 1987-01-16 |
DK222186D0 (da) | 1986-05-13 |
WO1986001717A1 (fr) | 1986-03-27 |
DK222186A (da) | 1986-05-13 |
ES8702137A1 (es) | 1987-01-16 |
JPH0417932B2 (fr) | 1992-03-26 |
CA1253079A (fr) | 1989-04-25 |
YU45988B (sh) | 1992-12-21 |
NO171887C (no) | 1993-05-19 |
FI87991B (fi) | 1992-12-15 |
NO171887B (no) | 1993-02-08 |
IE58490B1 (en) | 1993-09-22 |
FI871116A0 (fi) | 1987-03-13 |
JPS62500660A (ja) | 1987-03-19 |
PT81113B (pt) | 1987-10-20 |
AU4959485A (en) | 1986-04-08 |
FI87991C (fi) | 1993-03-25 |
ATE61733T1 (de) | 1991-04-15 |
PT81113A (en) | 1985-10-01 |
YU143985A (en) | 1987-10-31 |
IT1178511B (it) | 1987-09-09 |
DE3582251D1 (de) | 1991-04-25 |
IT8422678A0 (it) | 1984-09-14 |
AU588258B2 (en) | 1989-09-14 |
EP0226588B1 (fr) | 1991-03-20 |
EP0226588A1 (fr) | 1987-07-01 |
FI871116A (fi) | 1987-03-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK172710B1 (da) | Fremgangsmåde til fremstilling af en fast form til oral anvendelse baseret på nifedipin med reguleret frigørelse af aktivst | |
KR101899803B1 (ko) | 소듐 (2r,5s,13ar)-7,9-디옥소-10-((2,4,6-트리플루오로벤질)카르바모일)-2,3,4,5,7,9,13,13a-옥타히드로-2,5-메타노피리도[1',2':4,5]피라지노[2,1-b][1,3]옥사제핀-8-올레이트 | |
AU2009315441B2 (en) | Novel composition based on gamma-hydroxybutyric acid | |
EP3564244B1 (fr) | Formes cristallines du (2r,5s,13ar)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-méthanopyrido [1',2':4,5]pyrazino [2,1-b][1,3]oxazépine-10-carboxamide | |
EP4046994A1 (fr) | Formes de sel d'un inhibiteur de capside hiv | |
EP1986627A2 (fr) | Procede de traitement de maladies inflammatoires | |
WO2015130966A1 (fr) | Agents antiviraux | |
TW200540179A (en) | Macrolides | |
UA107564C2 (uk) | Фармацевтична композиція контрольованого вивільнення, яка містить нітазоксанід | |
TW200902089A (en) | Solid pharmaceutical composition | |
WO2011160434A1 (fr) | Procédé de préparation et procédé de contrôle de la qualité pour une injection de composé | |
CN118201615A (zh) | 喹唑啉酮化合物用于治疗癌症的新用途 | |
EP2334299A1 (fr) | Composition pharmaceutique comprenant du gaboxadol et un inhibiteur de pat1 ou d'oat | |
KR20210106477A (ko) | 5-브로모피리딘-3-일 3-데옥시-3-[4-(3,4,5-트리플루오로페닐)-1h-1,2,3-트리아졸-1-일]-1-티오-알파-d-갈락토피라노사이드의 비정질 형태 | |
TW202027750A (zh) | 治療癌症之套組及其方法 | |
EP3277278B1 (fr) | Forme galénique combinée d'un antagoniste de récepteur opioïde mu et d'un agent opioïde | |
CN113456605B (zh) | 一种索磷布韦与达拉他韦双层片及其制备方法 | |
CN116157127A (zh) | 化合物用于治疗口干燥症的用途 | |
EP3424500B1 (fr) | Composition pharmaceutique comprenant de famitinib | |
WO2024141073A1 (fr) | Combinaisons et compositions pharmaceutiques, et leurs procédés d'utilisation | |
EP4331569A1 (fr) | Préparation orale de sorafénib ou donafénib à faible dose et exposition élevée à un médicament, et application associée | |
CN105168177B (zh) | 沙格列汀胶囊及其制备方法 | |
CN114845723A (zh) | 包含喹唑啉衍生物或其盐的药物组合物 | |
AU2020282478A1 (en) | PARP inhibitor pellet preparation and preparation process therefor | |
JP2015508789A (ja) | 医薬製剤 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PUP | Patent expired |