DK171679B1 - Fremgangsmåde til fraskillelse af aktiveret humant protein C - Google Patents

Fremgangsmåde til fraskillelse af aktiveret humant protein C Download PDF

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Publication number
DK171679B1
DK171679B1 DK209288A DK209288A DK171679B1 DK 171679 B1 DK171679 B1 DK 171679B1 DK 209288 A DK209288 A DK 209288A DK 209288 A DK209288 A DK 209288A DK 171679 B1 DK171679 B1 DK 171679B1
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DK
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Prior art keywords
human protein
antibody
activated
activated human
protein
Prior art date
Application number
DK209288A
Other languages
Danish (da)
English (en)
Other versions
DK209288D0 (da
DK209288A (da
Inventor
Kenji Wakabayashi
Yoshihiko Sumi
Yataro Ichikawa
Yoichi Sakata
Nobuo Aoki
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of DK209288D0 publication Critical patent/DK209288D0/da
Publication of DK209288A publication Critical patent/DK209288A/da
Application granted granted Critical
Publication of DK171679B1 publication Critical patent/DK171679B1/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6464Protein C (3.4.21.69)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21069Protein C activated (3.4.21.69)

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK209288A 1987-04-17 1988-04-15 Fremgangsmåde til fraskillelse af aktiveret humant protein C DK171679B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9337787 1987-04-17
JP9337787 1987-04-17

Publications (3)

Publication Number Publication Date
DK209288D0 DK209288D0 (da) 1988-04-15
DK209288A DK209288A (da) 1988-10-18
DK171679B1 true DK171679B1 (da) 1997-03-10

Family

ID=14080613

Family Applications (1)

Application Number Title Priority Date Filing Date
DK209288A DK171679B1 (da) 1987-04-17 1988-04-15 Fremgangsmåde til fraskillelse af aktiveret humant protein C

Country Status (5)

Country Link
EP (1) EP0287028B1 (de)
KR (1) KR940010023B1 (de)
DE (1) DE3882411T2 (de)
DK (1) DK171679B1 (de)
NO (1) NO174056C (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2645865B1 (fr) * 1989-04-12 1991-07-12 Fondation Nale Transfusion San Procede de preparation de la proteine c activee et solution de proteine c activee ainsi obtenue
FR2658517B2 (fr) * 1989-04-12 1992-06-19 Fondation Nale Transfusion San Preparation de la proteine c activee et solution de proteine c activee ainsi obtenue.
AT402262B (de) * 1991-06-20 1997-03-25 Immuno Ag Arzneimittel enthaltend aktiviertes protein c
AT395596B (de) * 1991-06-20 1993-01-25 Immuno Ag Verfahren zur herstellung von aktiviertem protein c
AT402263B (de) 1991-06-20 1997-03-25 Immuno Ag Pharmazeutische präparation enthaltend eine thrombolytisch wirkende substanz
DE4320294A1 (de) * 1993-06-18 1994-12-22 Immuno Ag Verwendung von humanem Protein C zur Verhinderung und Behandlung von Thrombozytenablagerungen
US6989241B2 (en) 2000-10-02 2006-01-24 Oklahoma Medical Research Foundation Assay for rapid detection of human activated protein C and highly specific monoclonal antibody therefor
TW200407335A (en) * 2002-07-22 2004-05-16 Chugai Pharmaceutical Co Ltd Non-neutralizing antibody to inhibit the inactivation of activated protein C

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3485711D1 (de) * 1983-03-04 1992-06-17 Scripps Clinic Res Immunoadsorbens und verfahren zur zurueckgewinnung von vitamin-k-abhaengigen proteinen mittels dieses adsorbens.
GB8327860D0 (en) * 1983-10-18 1983-11-16 Fujisawa Pharmaceutical Co Monoclonal antiprotein c antibody
JPH0619352B2 (ja) * 1985-06-10 1994-03-16 帝人株式会社 ヒト・プロテインcの測定方法

Also Published As

Publication number Publication date
EP0287028A2 (de) 1988-10-19
NO881650D0 (no) 1988-04-15
DK209288D0 (da) 1988-04-15
EP0287028A3 (en) 1990-09-26
EP0287028B1 (de) 1993-07-21
NO881650L (no) 1988-10-18
DE3882411D1 (de) 1993-08-26
NO174056B (no) 1993-11-29
NO174056C (no) 1994-03-09
KR940010023B1 (ko) 1994-10-20
KR880012752A (ko) 1988-11-29
DE3882411T2 (de) 1993-12-16
DK209288A (da) 1988-10-18

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