DE3882411D1 - Verfahren zur trennung von aktiviertem menschlichem protein c. - Google Patents

Verfahren zur trennung von aktiviertem menschlichem protein c.

Info

Publication number
DE3882411D1
DE3882411D1 DE8888105800T DE3882411T DE3882411D1 DE 3882411 D1 DE3882411 D1 DE 3882411D1 DE 8888105800 T DE8888105800 T DE 8888105800T DE 3882411 T DE3882411 T DE 3882411T DE 3882411 D1 DE3882411 D1 DE 3882411D1
Authority
DE
Germany
Prior art keywords
human protein
activated human
separating activated
separating
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8888105800T
Other languages
English (en)
Other versions
DE3882411T2 (de
Inventor
Kenji Wakabayashi
Yoshihiko Sumi
Yataro Ichikawa
Yoichi Sakata
Nobuo Aoki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of DE3882411D1 publication Critical patent/DE3882411D1/de
Application granted granted Critical
Publication of DE3882411T2 publication Critical patent/DE3882411T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
DE88105800T 1987-04-17 1988-04-12 Verfahren zur Trennung von aktiviertem menschlichem Protein C. Expired - Lifetime DE3882411T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9337787 1987-04-17

Publications (2)

Publication Number Publication Date
DE3882411D1 true DE3882411D1 (de) 1993-08-26
DE3882411T2 DE3882411T2 (de) 1993-12-16

Family

ID=14080613

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88105800T Expired - Lifetime DE3882411T2 (de) 1987-04-17 1988-04-12 Verfahren zur Trennung von aktiviertem menschlichem Protein C.

Country Status (5)

Country Link
EP (1) EP0287028B1 (de)
KR (1) KR940010023B1 (de)
DE (1) DE3882411T2 (de)
DK (1) DK171679B1 (de)
NO (1) NO174056C (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2645865B1 (fr) * 1989-04-12 1991-07-12 Fondation Nale Transfusion San Procede de preparation de la proteine c activee et solution de proteine c activee ainsi obtenue
FR2658517B2 (fr) * 1989-04-12 1992-06-19 Fondation Nale Transfusion San Preparation de la proteine c activee et solution de proteine c activee ainsi obtenue.
AT395596B (de) * 1991-06-20 1993-01-25 Immuno Ag Verfahren zur herstellung von aktiviertem protein c
AT402262B (de) * 1991-06-20 1997-03-25 Immuno Ag Arzneimittel enthaltend aktiviertes protein c
AT402263B (de) * 1991-06-20 1997-03-25 Immuno Ag Pharmazeutische präparation enthaltend eine thrombolytisch wirkende substanz
DE4320294A1 (de) * 1993-06-18 1994-12-22 Immuno Ag Verwendung von humanem Protein C zur Verhinderung und Behandlung von Thrombozytenablagerungen
ATE464374T1 (de) 2000-10-02 2010-04-15 Oklahoma Med Res Found Assay zum schnellen nachweis vom humanen aktivierten protein c und hochspezifischer monoklonaler antikörper dagegen
TW200407335A (en) 2002-07-22 2004-05-16 Chugai Pharmaceutical Co Ltd Non-neutralizing antibody to inhibit the inactivation of activated protein C

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3485711D1 (de) * 1983-03-04 1992-06-17 Scripps Clinic Res Immunoadsorbens und verfahren zur zurueckgewinnung von vitamin-k-abhaengigen proteinen mittels dieses adsorbens.
GB8327860D0 (en) * 1983-10-18 1983-11-16 Fujisawa Pharmaceutical Co Monoclonal antiprotein c antibody
JPH0619352B2 (ja) * 1985-06-10 1994-03-16 帝人株式会社 ヒト・プロテインｃの測定方法

Also Published As

Publication number Publication date
EP0287028A2 (de) 1988-10-19
DK209288D0 (da) 1988-04-15
NO174056B (no) 1993-11-29
KR880012752A (ko) 1988-11-29
EP0287028A3 (en) 1990-09-26
DK209288A (da) 1988-10-18
NO174056C (no) 1994-03-09
DE3882411T2 (de) 1993-12-16
EP0287028B1 (de) 1993-07-21
NO881650D0 (no) 1988-04-15
NO881650L (no) 1988-10-18
KR940010023B1 (ko) 1994-10-20
DK171679B1 (da) 1997-03-10

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Legal Events

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