DE68901392D1 - Verfahren zur trennung von optisch aktiver (+-)-2-hydroxy-4-phenylbuttersaeure. - Google Patents

Verfahren zur trennung von optisch aktiver (+-)-2-hydroxy-4-phenylbuttersaeure.

Info

Publication number
DE68901392D1
DE68901392D1 DE8989102759T DE68901392T DE68901392D1 DE 68901392 D1 DE68901392 D1 DE 68901392D1 DE 8989102759 T DE8989102759 T DE 8989102759T DE 68901392 T DE68901392 T DE 68901392T DE 68901392 D1 DE68901392 D1 DE 68901392D1
Authority
DE
Germany
Prior art keywords
phenylbutteric
hydroxy
acid
optically active
separating optically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8989102759T
Other languages
English (en)
Inventor
Hiroyuki Nohira
Shinichi Yoshida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kuraray Co Ltd
Original Assignee
Kuraray Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kuraray Co Ltd filed Critical Kuraray Co Ltd
Application granted granted Critical
Publication of DE68901392D1 publication Critical patent/DE68901392D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8989102759T 1988-02-19 1989-02-17 Verfahren zur trennung von optisch aktiver (+-)-2-hydroxy-4-phenylbuttersaeure. Expired - Lifetime DE68901392D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3827388 1988-02-19

Publications (1)

Publication Number Publication Date
DE68901392D1 true DE68901392D1 (de) 1992-06-11

Family

ID=12520702

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989102759T Expired - Lifetime DE68901392D1 (de) 1988-02-19 1989-02-17 Verfahren zur trennung von optisch aktiver (+-)-2-hydroxy-4-phenylbuttersaeure.

Country Status (3)

Country Link
US (1) US4904822A (de)
EP (1) EP0329156B1 (de)
DE (1) DE68901392D1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2507163B2 (ja) * 1989-10-06 1996-06-12 株式会社クラレ 光学活性４―フェニル酪酸エステル誘導体のラセミ化方法
PL296247A1 (en) * 1990-09-21 1993-09-06 Smithkline Beecham Corp Method of crystallizing optical isomers acting as antagonists of leucotrienes
ES2035800B1 (es) * 1991-09-27 1994-02-01 Marga Investigacion Procedimiento de preparacion de los acidos (5) y (r) 2-substituidos -4-fenilbutricos, sus sales y derivados.
US5214201A (en) * 1991-12-12 1993-05-25 Smithkline Beecham Corporation Crystallization of optical isomers of leukotriene antagonists
US5290955A (en) * 1991-12-29 1994-03-01 Kuraray Co., Ltd. Process for producing L-ambrox
JPH06116217A (ja) * 1992-10-02 1994-04-26 Kuraray Co Ltd （±）−シス−４−アミノシクロペント−２−エンカルボン酸誘導体の光学分割法
JP3915015B2 (ja) * 1995-08-22 2007-05-16 味の素株式会社 光学活性２−ヒドロキシ−４−アリール酪酸またはそのエステルの製造方法
IN183408B (de) * 1996-11-20 1999-12-25 Kuraray Co
JPH11106363A (ja) * 1997-10-03 1999-04-20 Ajinomoto Co Inc 光学活性２−ヒドロキシメチル−３−フェニルプロピオン酸の製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4823435B1 (de) * 1969-09-25 1973-07-13
US3867434A (en) * 1971-11-04 1975-02-18 Rorer Inc William H Phenyl butyric acids and derivatives thereof
US3725437A (en) * 1970-09-16 1973-04-03 Sankyo Chem Ind Ltd Process for the preparation of {60 -hydroxy-{62 -phenypropionic acid derivatives and alkalimetal-or ammonium salts thereof
JPS5767516A (en) * 1980-09-24 1982-04-24 Microbial Chem Res Found Novel analgesic agent
JPH066539B2 (ja) * 1986-03-14 1994-01-26 三共株式会社 α−ハイドロキシカルボン酸誘導体の製法
JPH064578B2 (ja) * 1986-12-15 1994-01-19 鐘淵化学工業株式会社 光学活性シアノ化合物の製造方法

Also Published As

Publication number Publication date
EP0329156B1 (de) 1992-05-06
US4904822A (en) 1990-02-27
EP0329156A1 (de) 1989-08-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition